Detailed information    

insolico Bioinformatically predicted

Overview

Name   radC   Type   Machinery gene
Locus tag   ACB345_RS04180 Genome accession   NZ_CP167025
Coordinates   827121..827801 (+) Length   226 a.a.
NCBI ID   WP_031488296.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain Isolate     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 822121..832801
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACB345_RS04160 (ACB345_04160) aphA 822547..823278 (+) 732 WP_031488298.1 acid phosphatase AphA -
  ACB345_RS04165 (ACB345_04165) - 823456..824988 (+) 1533 WP_002995354.1 ClC family H(+)/Cl(-) exchange transporter -
  ACB345_RS04170 (ACB345_04170) - 825151..825765 (+) 615 WP_031488297.1 SGNH/GDSL hydrolase family protein -
  ACB345_RS04175 (ACB345_04175) - 825945..827072 (+) 1128 WP_002994399.1 AI-2E family transporter -
  ACB345_RS04180 (ACB345_04180) radC 827121..827801 (+) 681 WP_031488296.1 DNA repair protein RadC Machinery gene
  ACB345_RS04185 (ACB345_04185) - 827803..828498 (-) 696 WP_002989835.1 gamma-glutamyl-gamma-aminobutyrate hydrolase family protein -
  ACB345_RS04190 (ACB345_04190) - 828508..829152 (-) 645 WP_002984705.1 redox-sensing transcriptional repressor Rex -
  ACB345_RS04195 (ACB345_04195) - 829403..829750 (-) 348 WP_031488295.1 DUF1831 domain-containing protein -
  ACB345_RS04200 (ACB345_04200) - 829740..830867 (-) 1128 WP_031488294.1 cysteine desulfurase family protein -
  ACB345_RS04205 (ACB345_04205) - 830864..831844 (-) 981 WP_002989827.1 ribose-phosphate diphosphokinase -
  ACB345_RS04210 (ACB345_04210) - 831984..832562 (-) 579 WP_002984698.1 CYTH domain-containing protein -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 25730.91 Da        Isoelectric Point: 7.3866

>NTDB_id=931860 ACB345_RS04180 WP_031488296.1 827121..827801(+) (radC) [Streptococcus pyogenes strain Isolate]
MYSIKCDDNKAMPRERLMRLGAESLSNQELLAILLRTGNKEKHVLELSSYLLSHLDSLADFKKMSLQELQHLAGIGKVKA
IEIKAMIELVSRILATDKTLTDSVLTSVQVAEKMMAALGDKKQEHLVVLYLDNQNRIIEEKTTFIGTVRRSLAEPREILY
YACKNMATSLIVIHNHPSGNIEPSSNDYCFTEKIKRSCEDLGIICLDHIIVSYKDYYSFREKSTLF

Nucleotide


Download         Length: 681 bp        

>NTDB_id=931860 ACB345_RS04180 WP_031488296.1 827121..827801(+) (radC) [Streptococcus pyogenes strain Isolate]
ATGTATTCTATAAAATGTGATGATAATAAAGCCATGCCAAGAGAACGTTTGATGCGACTAGGAGCAGAGTCTCTAAGTAA
TCAAGAATTATTAGCAATTTTATTACGAACAGGTAATAAAGAAAAGCATGTCTTAGAGCTGTCATCCTATCTTTTATCGC
ATTTAGACAGTCTGGCAGATTTTAAAAAGATGTCTTTGCAAGAATTACAACATTTGGCAGGTATAGGAAAAGTTAAAGCG
ATTGAAATTAAAGCTATGATTGAGTTGGTTTCCCGAATTTTAGCGACAGATAAGACATTAACTGATAGCGTATTAACCAG
TGTTCAGGTCGCTGAAAAAATGATGGCAGCTTTAGGAGATAAAAAACAAGAGCATTTAGTCGTATTGTATTTAGATAATC
AAAATCGTATTATTGAAGAAAAAACTACTTTTATTGGGACTGTCCGACGTTCACTTGCAGAACCAAGAGAAATTTTATAC
TATGCCTGTAAAAATATGGCGACTAGTCTCATTGTTATTCATAATCATCCTTCAGGAAATATTGAACCTAGTTCTAACGA
TTATTGCTTTACTGAAAAAATAAAACGATCATGTGAAGATTTAGGCATTATCTGTCTAGATCACATTATCGTTAGCTATA
AAGATTATTATAGTTTTCGAGAAAAATCAACCCTTTTTTAA

Domains

Predicted by InterProScan.

RadC-like JAB domain (RadC)

(107-222)

UPF0758 N-terminal (UPF0758_N)

(10-81)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  radC Streptococcus pneumoniae TIGR4

57.522

100

0.575
  radC Streptococcus pneumoniae R6

57.08

100

0.571
  radC Streptococcus pneumoniae D39

57.08

100

0.571
  radC Streptococcus gordonii str. Challis substr. CH1

55.31

100

0.553
  ysxA/radC Bacillus subtilis subsp. subtilis str. 168

43.119

96.46

0.416
  radC Haemophilus influenzae Rd KW20

37.9

96.903

0.367