Detailed information    

insolico Bioinformatically predicted

Overview

Name   radC   Type   Machinery gene
Locus tag   ACB343_RS04185 Genome accession   NZ_CP167012
Coordinates   836218..836898 (+) Length   226 a.a.
NCBI ID   WP_011284774.1    Uniprot ID   Q48TN1
Organism   Streptococcus pyogenes strain Isolate 17     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 831218..841898
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACB343_RS04165 (ACB343_04165) aphA 831644..832375 (+) 732 WP_002984720.1 acid phosphatase AphA -
  ACB343_RS04170 (ACB343_04170) - 832553..834085 (+) 1533 WP_021341191.1 ClC family H(+)/Cl(-) exchange transporter -
  ACB343_RS04175 (ACB343_04175) - 834248..834862 (+) 615 WP_002984715.1 SGNH/GDSL hydrolase family protein -
  ACB343_RS04180 (ACB343_04180) - 835042..836169 (+) 1128 WP_002994399.1 AI-2E family transporter -
  ACB343_RS04185 (ACB343_04185) radC 836218..836898 (+) 681 WP_011284774.1 DNA repair protein RadC Machinery gene
  ACB343_RS04190 (ACB343_04190) - 836900..837595 (-) 696 WP_011284775.1 gamma-glutamyl-gamma-aminobutyrate hydrolase family protein -
  ACB343_RS04195 (ACB343_04195) - 837605..838249 (-) 645 WP_002984705.1 redox-sensing transcriptional repressor Rex -
  ACB343_RS04200 (ACB343_04200) - 838501..838848 (-) 348 WP_002989831.1 DUF1831 domain-containing protein -
  ACB343_RS04205 (ACB343_04205) - 838838..839965 (-) 1128 WP_002989829.1 cysteine desulfurase family protein -
  ACB343_RS04210 (ACB343_04210) - 839962..840942 (-) 981 WP_002989827.1 ribose-phosphate diphosphokinase -
  ACB343_RS04215 (ACB343_04215) - 841082..841660 (-) 579 WP_002989824.1 CYTH domain-containing protein -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 25776.98 Da        Isoelectric Point: 7.3866

>NTDB_id=930726 ACB343_RS04185 WP_011284774.1 836218..836898(+) (radC) [Streptococcus pyogenes strain Isolate 17]
MYSIKCDDNKAMPRERLMRLGAESLSNQELLAILLRTGNKEKHVLELSSYLLSHLDSLADFKKMSLQELQHLAGIGKVKA
IEIKAMIELVSRILATDKTLTDSVLTSVQVAEKMMAALGDKKQEHLVVLYLDNQNRIFEEKTIFIGTVRRSLAEPREILY
YACKNMATSLIVIHNHPSGNIEPSSNDYCFTEKIKRSCEDLGIICLDHIIVSYKDYYSFREKSTLF

Nucleotide


Download         Length: 681 bp        

>NTDB_id=930726 ACB343_RS04185 WP_011284774.1 836218..836898(+) (radC) [Streptococcus pyogenes strain Isolate 17]
ATGTATTCTATAAAATGTGATGATAATAAAGCCATGCCAAGAGAACGTTTGATGCGACTAGGAGCAGAGTCTCTAAGTAA
TCAAGAATTATTAGCAATTTTATTACGAACAGGTAATAAAGAAAAGCATGTCTTAGAGCTGTCATCCTATCTTTTATCGC
ATTTAGACAGTCTGGCAGATTTTAAAAAGATGTCTTTGCAAGAATTACAACATTTGGCAGGTATAGGAAAAGTTAAAGCG
ATTGAAATTAAAGCTATGATTGAGTTGGTTTCCCGAATTTTAGCGACCGATAAGACATTAACTGATAGCGTATTAACCAG
TGTTCAGGTCGCTGAAAAAATGATGGCAGCTTTAGGAGATAAAAAACAAGAGCATTTAGTCGTATTGTATTTAGATAATC
AAAATCGTATTTTTGAAGAAAAAACTATTTTTATTGGGACTGTCCGACGTTCACTTGCAGAACCAAGAGAAATTTTATAC
TATGCCTGTAAAAATATGGCGACTAGTCTCATTGTTATTCATAATCATCCTTCAGGAAATATTGAACCTAGTTCTAACGA
TTATTGCTTTACTGAAAAAATAAAACGATCATGTGAAGATTTAGGCATTATCTGTCTAGATCACATTATCGTTAGCTATA
AAGATTATTATAGTTTTCGAGAAAAATCAACCCTTTTTTAA

Domains

Predicted by InterProScan.

RadC-like JAB domain (RadC)

(107-222)

UPF0758 N-terminal (UPF0758_N)

(10-81)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q48TN1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  radC Streptococcus pneumoniae TIGR4

57.522

100

0.575
  radC Streptococcus pneumoniae R6

57.08

100

0.571
  radC Streptococcus pneumoniae D39

57.08

100

0.571
  radC Streptococcus gordonii str. Challis substr. CH1

55.31

100

0.553
  ysxA/radC Bacillus subtilis subsp. subtilis str. 168

42.661

96.46

0.412
  radC Haemophilus influenzae Rd KW20

37.443

96.903

0.363