Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   ACB352_RS06140 Genome accession   NZ_CP167009
Coordinates   1172322..1172798 (-) Length   158 a.a.
NCBI ID   WP_002984880.1    Uniprot ID   A0A0H2UU18
Organism   Streptococcus pyogenes strain Isolate 22     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1167322..1177798
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACB352_RS06125 (ACB352_06125) fbp54 1168135..1169787 (+) 1653 WP_002991968.1 Rqc2 family fibronectin-binding protein Fbp54 -
  ACB352_RS06130 (ACB352_06130) - 1169846..1171093 (-) 1248 WP_002990000.1 tetratricopeptide repeat protein -
  ACB352_RS06135 (ACB352_06135) - 1171083..1172264 (-) 1182 WP_011284730.1 AI-2E family transporter -
  ACB352_RS06140 (ACB352_06140) mutX 1172322..1172798 (-) 477 WP_002984880.1 8-oxo-dGTP diphosphatase Machinery gene
  ACB352_RS06145 (ACB352_06145) rfbB 1173019..1174059 (-) 1041 WP_011284729.1 dTDP-glucose 4,6-dehydratase -
  ACB352_RS06150 (ACB352_06150) - 1174303..1174896 (-) 594 WP_002990099.1 dTDP-4-dehydrorhamnose 3,5-epimerase family protein -
  ACB352_RS06155 (ACB352_06155) rfbA 1174896..1175765 (-) 870 WP_371399918.1 glucose-1-phosphate thymidylyltransferase RfbA -
  ACB352_RS06160 (ACB352_06160) - 1175824..1176930 (-) 1107 WP_011284727.1 FAD-binding oxidoreductase -
  ACB352_RS06165 (ACB352_06165) - 1176970..1177758 (-) 789 WP_021340967.1 Nif3-like dinuclear metal center hexameric protein -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18462.68 Da        Isoelectric Point: 4.3268

>NTDB_id=930459 ACB352_RS06140 WP_002984880.1 1172322..1172798(-) (mutX) [Streptococcus pyogenes strain Isolate 22]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=930459 ACB352_RS06140 WP_002984880.1 1172322..1172798(-) (mutX) [Streptococcus pyogenes strain Isolate 22]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAGGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCCGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTCCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UU18

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

70.253

100

0.703