Detailed information NTG0930392

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: ACB353_RS08940
• Genome accession: NZ_CP167008
• Coordinates: 1804608..1805375 (-)
• Length: 255 a.a.
• NCBI ID: WP_003058809.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain Isolate 23
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1799608..1810375

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB353_RS08925 (ACB353_08925)	hexB	1800126..1802108 (-)	1983	WP_371397166.1	DNA mismatch repair endonuclease MutL	Machinery gene
ACB353_RS08930 (ACB353_08930)	-	1802203..1803354 (-)	1152	WP_003058754.1	site-specific integrase	-
ACB353_RS08935 (ACB353_08935)	-	1803603..1803746 (+)	144	WP_011185066.1	putative holin-like toxin	-
ACB353_RS08940 (ACB353_08940)	irvR	1804608..1805375 (-)	768	WP_003058809.1	helix-turn-helix transcriptional regulator	Regulator
ACB353_RS08945 (ACB353_08945)	-	1805529..1805735 (+)	207	WP_002992503.1	helix-turn-helix transcriptional regulator	-
ACB353_RS08950 (ACB353_08950)	-	1805769..1805969 (+)	201	WP_002992502.1	helix-turn-helix domain-containing protein	-
ACB353_RS08955 (ACB353_08955)	-	1805990..1806397 (+)	408	WP_002992501.1	hypothetical protein	-
ACB353_RS08960 (ACB353_08960)	-	1806410..1806532 (+)	123	WP_011285272.1	hypothetical protein	-
ACB353_RS08965 (ACB353_08965)	-	1806815..1807336 (+)	522	WP_002992498.1	Rha family transcriptional regulator	-
ACB353_RS08970 (ACB353_08970)	-	1807584..1807757 (+)	174	WP_000132665.1	hypothetical protein	-
ACB353_RS08975 (ACB353_08975)	-	1807975..1808148 (+)	174	WP_000074663.1	hypothetical protein	-
ACB353_RS08980 (ACB353_08980)	-	1808336..1808740 (+)	405	WP_227868741.1	hypothetical protein	-
ACB353_RS08985 (ACB353_08985)	-	1808842..1809174 (+)	333	WP_011285276.1	hypothetical protein	-
ACB353_RS08990 (ACB353_08990)	-	1809174..1809365 (+)	192	WP_021340709.1	hypothetical protein	-
ACB353_RS08995 (ACB353_08995)	-	1809377..1809706 (+)	330	WP_003058810.1	hypothetical protein	-
ACB353_RS09000 (ACB353_09000)	-	1809709..1809981 (+)	273	WP_010922766.1	hypothetical protein	-

Sequence

Protein

• Length: 255 a.a.
• Molecular weight: 28725.00 Da
• Isoelectric Point: 4.3544

>NTDB_id=930392 ACB353_RS08940 WP_003058809.1 1804608..1805375(-) (irvR) [Streptococcus pyogenes strain Isolate 23]
MAKNSPQDLINREIFSTNLNMLMAKKNIKQIDIHNKLGIPKSTITGYVKGRSLPTAGNVQKLADFFGVLKSDIDPRFDSN
NIETNSNIIPSTLQKVTSTLSQLEHKRQLNVLDYAETQLEQQNTVEEPQATYYTYNYYDHAASAGTGQYLNDVQVETIEL
PVDYDADFVIPVYGDSMEPEYHSGDYVFIKLSINLSDGDIGVFEYYGDAYIKQLVINDSGAFLHSLNDKYDDILIDRDSD
FRIIGEVIGSFTSKS

Nucleotide

• Length: 768 bp

>NTDB_id=930392 ACB353_RS08940 WP_003058809.1 1804608..1805375(-) (irvR) [Streptococcus pyogenes strain Isolate 23]
ATGGCTAAAAATAGTCCCCAAGATTTAATAAATAGAGAAATTTTCTCAACAAATCTCAACATGCTTATGGCTAAAAAGAA
TATCAAACAGATAGATATTCACAACAAACTAGGAATACCTAAGAGTACGATAACTGGCTATGTTAAAGGTCGTTCACTCC
CAACTGCTGGAAACGTTCAAAAGTTGGCGGACTTCTTCGGAGTTCTAAAATCAGACATTGACCCCCGTTTTGATTCTAAT
AATATTGAAACAAATAGTAATATTATCCCATCAACCCTACAAAAAGTAACATCTACTTTATCTCAGCTAGAACACAAGCG
ACAATTAAACGTCCTTGATTATGCTGAAACACAATTAGAACAACAAAACACAGTAGAAGAACCACAAGCCACCTACTACA
CTTACAACTACTACGACCACGCAGCTTCAGCTGGTACAGGTCAGTATCTAAATGATGTACAAGTAGAAACAATTGAATTA
CCAGTCGATTACGACGCTGATTTTGTCATACCGGTTTATGGCGATTCTATGGAACCCGAATACCATTCTGGGGACTATGT
ATTTATCAAACTATCTATTAACCTGTCAGATGGTGATATAGGAGTTTTTGAGTATTACGGTGATGCTTATATCAAACAAC
TTGTTATAAACGATTCTGGAGCGTTTCTGCATAGTCTGAACGACAAGTATGACGATATACTCATAGATAGAGATAGTGAT
TTCCGTATTATCGGAGAAGTTATTGGGAGTTTTACATCTAAATCATGA

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (23-68)

• Peptidase S24-like (Peptidase_S24) (141-248)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	34	100	0.4