Detailed information    

insolico Bioinformatically predicted

Overview

Name   radC   Type   Machinery gene
Locus tag   ACB354_RS04520 Genome accession   NZ_CP167004
Coordinates   834732..835412 (+) Length   226 a.a.
NCBI ID   WP_011184496.1    Uniprot ID   Q5XC90
Organism   Streptococcus pyogenes strain Isolate 28     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 829732..840412
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACB354_RS04500 (ACB354_04500) aphA 830158..830889 (+) 732 WP_002984720.1 acid phosphatase AphA -
  ACB354_RS04505 (ACB354_04505) - 831067..832599 (+) 1533 WP_011888889.1 ClC family H(+)/Cl(-) exchange transporter -
  ACB354_RS04510 (ACB354_04510) - 832762..833376 (+) 615 WP_011017748.1 SGNH/GDSL hydrolase family protein -
  ACB354_RS04515 (ACB354_04515) - 833556..834683 (+) 1128 WP_032463878.1 AI-2E family transporter -
  ACB354_RS04520 (ACB354_04520) radC 834732..835412 (+) 681 WP_011184496.1 DNA repair protein RadC Machinery gene
  ACB354_RS04525 (ACB354_04525) - 835414..836109 (-) 696 WP_011184497.1 gamma-glutamyl-gamma-aminobutyrate hydrolase family protein -
  ACB354_RS04530 (ACB354_04530) - 836119..836763 (-) 645 WP_002984705.1 redox-sensing transcriptional repressor Rex -
  ACB354_RS04535 (ACB354_04535) - 837018..837365 (-) 348 WP_002989831.1 DUF1831 domain-containing protein -
  ACB354_RS04540 (ACB354_04540) - 837355..838482 (-) 1128 WP_011184498.1 cysteine desulfurase family protein -
  ACB354_RS04545 (ACB354_04545) - 838479..839459 (-) 981 WP_002989827.1 ribose-phosphate diphosphokinase -
  ACB354_RS04550 (ACB354_04550) - 839599..840177 (-) 579 WP_159328612.1 CYTH domain-containing protein -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 25755.02 Da        Isoelectric Point: 7.3866

>NTDB_id=929977 ACB354_RS04520 WP_011184496.1 834732..835412(+) (radC) [Streptococcus pyogenes strain Isolate 28]
MYSIKCDDNKAMPRERLMRLGAESLSNQELLAILLRTGNKEKHVLELSSYLLSHLDSLADFKKMSLQELQHLAGIGKVKA
IEIKAMIELVSRILAIDKTLTDSVLTSVQVAEKMMAALGDKKQEHLVVLYLDNQNRIIEEKTIFIGTVRRSLAEPREILY
YACKNMATSLIVIHNHPSGNIEPSSNDYCFTEKIKRSCEDLGIICLDHIIVSYKDYYSFREKSTLF

Nucleotide


Download         Length: 681 bp        

>NTDB_id=929977 ACB354_RS04520 WP_011184496.1 834732..835412(+) (radC) [Streptococcus pyogenes strain Isolate 28]
ATGTATTCTATAAAATGTGATGATAATAAAGCCATGCCAAGAGAACGTTTGATGCGACTAGGAGCAGAGTCTCTAAGTAA
TCAAGAATTATTAGCAATTTTATTACGAACAGGTAATAAAGAAAAGCATGTCTTAGAGCTGTCATCCTATCTTTTATCGC
ATTTAGACAGTCTGGCAGATTTTAAAAAGATGTCTTTGCAAGAATTACAACATTTGGCAGGTATAGGAAAAGTTAAAGCG
ATTGAAATTAAAGCTATGATTGAGTTGGTTTCCCGAATTTTAGCGATCGATAAGACATTAACTGATAGCGTATTAACCAG
TGTTCAGGTCGCTGAAAAAATGATGGCAGCTTTAGGAGATAAAAAACAAGAGCATTTAGTCGTATTGTATTTAGATAATC
AAAATCGTATTATTGAAGAAAAAACTATTTTTATTGGGACTGTCCGACGTTCACTTGCAGAACCAAGAGAAATTTTATAC
TATGCCTGTAAAAATATGGCGACTAGTCTCATTGTTATTCATAATCATCCTTCAGGAAATATTGAACCTAGTTCTAACGA
TTATTGCTTTACTGAAAAAATAAAACGATCATGTGAAGATTTAGGCATTATCTGTCTAGATCACATTATCGTTAGCTATA
AAGATTATTATAGTTTTCGAGAAAAATCAACCCTTTTTTAA

Domains

Predicted by InterProScan.

RadC-like JAB domain (RadC)

(107-222)

UPF0758 N-terminal (UPF0758_N)

(10-81)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5XC90

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  radC Streptococcus pneumoniae TIGR4

57.965

100

0.58
  radC Streptococcus pneumoniae R6

57.522

100

0.575
  radC Streptococcus pneumoniae D39

57.522

100

0.575
  radC Streptococcus gordonii str. Challis substr. CH1

55.752

100

0.558
  ysxA/radC Bacillus subtilis subsp. subtilis str. 168

42.593

95.575

0.407
  radC Haemophilus influenzae Rd KW20

37.9

96.903

0.367