Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   VKP36_RS01335 Genome accession   NZ_CP142357
Coordinates   245689..246450 (+) Length   253 a.a.
NCBI ID   WP_002986029.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain AW-534     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 240689..251450
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VKP36_RS01320 (VKP36_01320) - 240947..242515 (-) 1569 WP_032464806.1 ABC transporter substrate-binding protein/permease -
  VKP36_RS01325 (VKP36_01325) - 242713..244638 (+) 1926 WP_326625019.1 DUF2207 domain-containing protein -
  VKP36_RS01330 (VKP36_01330) - 244704..245543 (+) 840 WP_326625021.1 undecaprenyl-diphosphate phosphatase -
  VKP36_RS01335 (VKP36_01335) mecA 245689..246450 (+) 762 WP_002986029.1 adaptor protein MecA Regulator
  VKP36_RS01340 (VKP36_01340) - 246457..247626 (+) 1170 WP_326625023.1 MraY family glycosyltransferase -
  VKP36_RS01345 (VKP36_01345) sufC 247748..248518 (+) 771 WP_136020939.1 Fe-S cluster assembly ATPase SufC -
  VKP36_RS01350 (VKP36_01350) sufD 248613..249875 (+) 1263 WP_023612423.1 Fe-S cluster assembly protein SufD -
  VKP36_RS01355 (VKP36_01355) - 249906..251132 (+) 1227 WP_326625029.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 253 a.a.        Molecular weight: 29051.72 Da        Isoelectric Point: 4.1622

>NTDB_id=925362 VKP36_RS01335 WP_002986029.1 245689..246450(+) (mecA) [Streptococcus pyogenes strain AW-534]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEI
NKDINLEDLAEFGDMSQMTPEDFFKSLEQSMREKGDVKAHEKLEKIEEIMEDVVEATLANQSEAADPSTNHESEPLDYVH
YVLDFSTITEAVAFAKTIDFSIEASELYKGSNCYHMTILLDVQQQPSYFANVMYARLIEHANPGSKTRAYLQEHGLQLML
DGAVEQLQKIELG

Nucleotide


Download         Length: 762 bp        

>NTDB_id=925362 VKP36_RS01335 WP_002986029.1 245689..246450(+) (mecA) [Streptococcus pyogenes strain AW-534]
ATGGAAATGAAACAAATTAGCGAGACAACGCTAAAAATAACAATTAGTATGGACGATTTAGAAGAAAGAGGAATGGAGTT
GAAAGATTTCTTGATTCCTCAAGAAAAAACAGAAGAGTTTTTCTATTCTGTGATGGACGAACTCGATCTTCCAGATAATT
TTAAAGATAGTGGTATGCTTAGTTTTCGAGTGACTCCACGCAAGGACCGTCTAGATGTTTTTGTTACCAAATCTGAGATA
AATAAAGATATTAATCTTGAAGATTTAGCAGAGTTTGGTGATATGTCCCAAATGACTCCGGAAGATTTTTTCAAGAGCTT
GGAGCAATCCATGCGTGAAAAGGGAGATGTCAAAGCTCATGAAAAATTGGAAAAAATTGAAGAGATAATGGAAGATGTTG
TTGAAGCTACTCTAGCTAATCAGTCTGAGGCGGCTGATCCATCAACTAATCATGAGTCAGAACCTTTAGACTATGTCCAT
TATGTATTGGATTTTTCAACGATTACAGAGGCAGTGGCTTTTGCTAAAACGATTGATTTTTCGATAGAAGCTTCAGAGTT
ATATAAGGGGAGCAACTGCTACCATATGACTATTTTATTAGATGTTCAGCAACAACCATCTTATTTTGCGAATGTCATGT
ATGCGAGATTGATTGAGCATGCAAACCCTGGATCAAAAACAAGAGCTTATTTACAAGAGCATGGCTTACAATTGATGCTT
GATGGTGCTGTTGAGCAATTACAAAAGATTGAGTTGGGATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

63.2

98.814

0.625
  mecA Streptococcus thermophilus LMD-9

56.225

98.419

0.553
  mecA Streptococcus thermophilus LMG 18311

55.422

98.419

0.545
  mecA Streptococcus pneumoniae Rx1

48.235

100

0.486
  mecA Streptococcus pneumoniae D39

48.235

100

0.486
  mecA Streptococcus pneumoniae R6

48.235

100

0.486
  mecA Streptococcus pneumoniae TIGR4

48.235

100

0.486