Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   VKP53_RS01495 Genome accession   NZ_CP142354
Coordinates   272107..272868 (+) Length   253 a.a.
NCBI ID   WP_326674892.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain 6745-99     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 267107..277868
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VKP53_RS01480 (VKP53_01480) - 267365..268933 (-) 1569 WP_326674887.1 ABC transporter substrate-binding protein/permease -
  VKP53_RS01485 (VKP53_01485) - 269131..271056 (+) 1926 WP_326674889.1 DUF2207 domain-containing protein -
  VKP53_RS01490 (VKP53_01490) - 271122..271961 (+) 840 WP_032460423.1 undecaprenyl-diphosphate phosphatase -
  VKP53_RS01495 (VKP53_01495) mecA 272107..272868 (+) 762 WP_326674892.1 adaptor protein MecA Regulator
  VKP53_RS01500 (VKP53_01500) - 272875..274044 (+) 1170 WP_002991122.1 glycosyltransferase family 4 protein -
  VKP53_RS01505 (VKP53_01505) sufC 274166..274936 (+) 771 WP_002986023.1 Fe-S cluster assembly ATPase SufC -
  VKP53_RS01510 (VKP53_01510) sufD 275031..276293 (+) 1263 WP_047235146.1 Fe-S cluster assembly protein SufD -
  VKP53_RS01515 (VKP53_01515) - 276324..277550 (+) 1227 WP_111704520.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 253 a.a.        Molecular weight: 29033.69 Da        Isoelectric Point: 4.1622

>NTDB_id=925200 VKP53_RS01495 WP_326674892.1 272107..272868(+) (mecA) [Streptococcus pyogenes strain 6745-99]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEI
NKDINLEDLAEFGDMSQLTPEDFFKSLEQSMREKGDVKAHEKLEKIEEIMEDVVEATLANQSEAADPSTNHESEPLDYVH
YVLDFSTITEAVAFAKTIDFSIEASELYKGSNCYHMTILLDVQQQPSYFANVMYARLIEHANPGSKTRAYLQEHGLQLML
DGAVEQLQKIELG

Nucleotide


Download         Length: 762 bp        

>NTDB_id=925200 VKP53_RS01495 WP_326674892.1 272107..272868(+) (mecA) [Streptococcus pyogenes strain 6745-99]
ATGGAAATGAAACAAATTAGCGAGACAACGCTAAAAATAACAATTAGTATGGACGATTTAGAAGAAAGAGGAATGGAGTT
GAAAGATTTCTTGATTCCTCAAGAAAAAACAGAAGAGTTTTTCTATTCTGTGATGGACGAACTCGATCTTCCAGATAATT
TTAAAGATAGTGGTATGCTTAGTTTTCGAGTGACTCCACGCAAGGACCGTCTAGATGTTTTTGTTACCAAATCTGAGATA
AATAAAGATATTAATCTTGAAGATTTAGCAGAGTTTGGTGATATGTCCCAATTGACTCCGGAAGATTTTTTCAAGAGCTT
GGAGCAATCCATGCGTGAAAAGGGAGATGTCAAAGCTCATGAAAAATTGGAAAAAATTGAAGAGATAATGGAAGATGTTG
TTGAAGCCACTCTAGCTAATCAGTCTGAGGCGGCTGATCCATCAACTAATCATGAGTCAGAACCTTTAGACTATGTCCAT
TATGTATTGGATTTTTCAACGATTACAGAGGCAGTGGCTTTTGCTAAAACGATTGATTTTTCGATAGAAGCTTCAGAGTT
ATATAAGGGGAGCAACTGCTACCATATGACTATTTTATTAGATGTTCAGCAACAACCATCTTATTTTGCGAATGTCATGT
ATGCGAGATTGATTGAGCATGCAAACCCTGGATCAAAAACAAGAGCTTATTTACAAGAGCATGGCTTACAATTGATGCTT
GATGGTGCTGTTGAGCAATTACAAAAGATTGAGTTGGGATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

62.8

98.814

0.621
  mecA Streptococcus thermophilus LMD-9

56.627

98.419

0.557
  mecA Streptococcus thermophilus LMG 18311

55.823

98.419

0.549
  mecA Streptococcus pneumoniae Rx1

47.843

100

0.482
  mecA Streptococcus pneumoniae D39

47.843

100

0.482
  mecA Streptococcus pneumoniae R6

47.843

100

0.482
  mecA Streptococcus pneumoniae TIGR4

47.843

100

0.482