Detailed information NTG0092515

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: Llc71_RS09715
• Genome accession: NZ_AP025520
• Coordinates: 1932749..1934959 (-)
• Length: 736 a.a.
• NCBI ID: WP_046124455.1
• Uniprot ID: A0A1E7G5C4
• Organism: Lactococcus cremoris strain 7-1
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1927749..1939959

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Llc71_RS09685 (Llc71_19430)	atpA	1927790..1929292 (-)	1503	WP_014572214.1	F0F1 ATP synthase subunit alpha	-
Llc71_RS09690 (Llc71_19440)	-	1929481..1930008 (-)	528	WP_011835692.1	F0F1 ATP synthase subunit delta	-
Llc71_RS09695 (Llc71_19450)	atpF	1930010..1930516 (-)	507	WP_010906128.1	F0F1 ATP synthase subunit B	-
Llc71_RS09700 (Llc71_19460)	atpB	1930531..1931244 (-)	714	WP_004255255.1	F0F1 ATP synthase subunit A	-
Llc71_RS09705 (Llc71_19470)	-	1931291..1931506 (-)	216	WP_004255250.1	F0F1 ATP synthase subunit C	-
Llc71_RS09710 (Llc71_19480)	-	1931689..1932465 (-)	777	WP_011835694.1	alpha/beta hydrolase family protein	-
Llc71_RS09715 (Llc71_19490)	comEC	1932749..1934959 (-)	2211	WP_046124455.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
Llc71_RS09720 (Llc71_19500)	comEA	1934940..1935554 (-)	615	WP_075070464.1	helix-hairpin-helix domain-containing protein	Machinery gene
Llc71_RS09725 (Llc71_19510)	-	1935654..1937015 (-)	1362	WP_011835696.1	ABC transporter permease	-
Llc71_RS09730 (Llc71_19520)	-	1937012..1937944 (-)	933	WP_046124456.1	ABC transporter ATP-binding protein	-
Llc71_RS09735	-	1938050..1938448 (-)	399	WP_042747837.1	hypothetical protein	-
Llc71_RS09740 (Llc71_19530)	-	1938565..1939125 (-)	561	WP_011835699.1	GNAT family N-acetyltransferase	-

Sequence

Protein

• Length: 736 a.a.
• Molecular weight: 84671.63 Da
• Isoelectric Point: 9.7089

>NTDB_id=92515 Llc71_RS09715 WP_046124455.1 1932749..1934959(-) (comEC) [Lactococcus cremoris strain 7-1]
MRFLLIKFTLIFLTYLVVLLYFCIFTYNLPLLILFICSILLALFRKYYLMIPILIVFAVFFLLINSLSIRDNENQPKNLS
KIELIPDTIQVNGDLLSFQGRMNGQKYQVYDTLKSLKEKEFYQNLSQNCQLSFTGNLEIPEIQRNFNGFDDQKYLASQNI
YRQITIQQITNVEIKKNFDLHTLRRKAIVWTQNHFPKPMSDYMTGLLFGFLSKDFNQMSDIYSSLGIIHLFALSGMQVNF
FIDWFRKILLRMGLTRERVNLVQIPFSIFYAFMTGLSVSVLRALFQKNIRLTSLDNIGVTTLVLMLISPKFLLTTGGQLT
LFYAFVISMLNHSFSNLNGLKKVLTESSVLSLCVLPLLIFDFHIFQPLSILLTIIFGFLFDFMLLPLLLCCFLISFLGFS
LNLNFIFQILEWLVHKVDLPLHYPFVLGKPSSLELIILFVLIGLFVDSFSHKKRRFFLIGFIFLFFFITKNPMRASITAV
DIGQGDSIFLQDKFNKENILIDTGGQLALPQKNWQKAQTQSNADKTLIPYLESMGVAHIDQLILTHTDADHVGDFLSLAD
KIKIREIWVSPGELTNSSFVEKLKKAKIPIHVSKVGDKIPIFDSFLQVLSNGYTKKGDNNDSIVTYGNFYHTKFLFTGDL
EQEGEKKLLQNYPKLQVDVLKVGHHGSKTSSSPEFIKEIHPKLALISVGKANRYGHPNQETLETLAKYQVKTLRTDQKGA
IKLTEVNQQWQIKTVR

Nucleotide

• Length: 2211 bp

>NTDB_id=92515 Llc71_RS09715 WP_046124455.1 1932749..1934959(-) (comEC) [Lactococcus cremoris strain 7-1]
ATGAGATTTCTATTGATTAAATTTACCCTGATTTTTCTAACTTATCTTGTTGTGCTACTTTATTTTTGTATCTTTACTTA
CAATTTACCCTTGCTTATTTTATTTATTTGCTCAATTTTACTAGCTTTATTCAGAAAATATTATCTAATGATTCCGATAT
TAATTGTTTTTGCTGTATTTTTTCTGTTAATCAATAGTCTTAGTATTAGGGATAATGAAAATCAACCAAAAAATCTCTCA
AAAATTGAATTAATTCCAGATACAATCCAAGTCAATGGTGATTTATTGAGTTTTCAGGGGAGAATGAATGGACAAAAATA
TCAAGTCTATGACACATTGAAAAGTCTAAAAGAGAAAGAGTTTTATCAGAACTTAAGTCAAAATTGTCAGTTAAGTTTCA
CAGGAAACCTTGAAATACCAGAAATTCAGCGAAATTTTAATGGTTTTGATGACCAAAAATATTTAGCTAGTCAAAATATC
TATCGACAAATTACCATCCAGCAAATTACAAATGTGGAAATAAAAAAGAATTTTGACCTTCATACTTTAAGGCGAAAGGC
AATTGTTTGGACACAAAATCATTTTCCAAAACCGATGAGTGACTATATGACAGGTTTGCTTTTTGGCTTTTTAAGTAAGG
ATTTTAATCAGATGAGCGATATTTACAGCTCTTTAGGAATTATTCATCTTTTTGCTCTATCAGGAATGCAAGTAAATTTT
TTTATTGACTGGTTTCGTAAAATACTACTTCGCATGGGACTGACGAGAGAAAGAGTGAATCTTGTTCAAATTCCATTTTC
GATTTTTTATGCTTTTATGACGGGATTATCGGTTTCAGTTTTAAGAGCCCTTTTTCAAAAAAATATTCGTCTGACTTCTT
TGGATAATATCGGAGTGACGACATTAGTTTTGATGCTCATAAGTCCAAAATTTTTACTGACGACTGGCGGTCAGCTTACC
TTGTTTTATGCTTTTGTCATTTCGATGCTTAACCATTCTTTTTCTAATTTAAATGGATTGAAAAAAGTGCTGACAGAATC
ATCAGTCCTTTCACTTTGTGTTCTTCCGTTACTCATCTTTGATTTCCATATTTTTCAGCCTCTTTCAATATTATTAACAA
TTATATTTGGTTTTCTTTTTGATTTTATGCTGCTCCCGCTGCTTTTATGCTGTTTTCTTATATCATTTTTGGGATTTTCG
CTCAATTTAAATTTTATTTTTCAAATTCTAGAATGGCTAGTTCATAAAGTTGATTTACCCTTACATTACCCTTTTGTTTT
GGGGAAACCTAGTTCACTCGAATTAATTATTCTATTTGTGTTAATTGGTTTATTCGTAGATTCATTTTCTCATAAAAAAA
GGAGATTTTTTTTAATTGGATTTATATTTTTATTTTTTTTCATCACTAAAAATCCAATGAGAGCAAGCATTACAGCGGTT
GATATCGGACAAGGCGATAGTATTTTTCTACAAGATAAGTTTAATAAAGAAAACATTCTGATTGATACTGGGGGACAACT
TGCTCTTCCTCAAAAAAATTGGCAAAAAGCGCAGACGCAATCAAATGCTGACAAAACGCTTATTCCTTATTTAGAATCCA
TGGGGGTGGCTCATATTGACCAACTTATTCTGACTCATACAGATGCTGACCATGTTGGTGATTTCTTATCCTTAGCTGAT
AAAATAAAAATAAGAGAAATCTGGGTCAGTCCGGGAGAATTAACCAACAGTAGTTTTGTGGAAAAATTAAAAAAAGCAAA
AATTCCGATTCATGTTAGTAAAGTTGGGGATAAAATTCCGATTTTTGATAGTTTTCTTCAAGTTTTATCAAATGGTTACA
CTAAAAAAGGTGATAATAATGATTCCATAGTGACTTATGGAAACTTTTACCATACAAAATTTCTTTTTACAGGAGATTTG
GAACAAGAAGGAGAAAAAAAGCTTCTACAAAATTATCCCAAATTACAGGTAGATGTGTTAAAAGTGGGGCATCATGGCAG
TAAAACAAGTTCAAGTCCGGAATTCATCAAAGAGATACATCCTAAACTTGCACTAATCTCGGTTGGAAAAGCTAATCGCT
ATGGTCATCCCAATCAAGAAACTTTAGAAACCTTAGCCAAATATCAGGTAAAGACACTCAGAACTGACCAAAAAGGGGCA
ATAAAATTAACAGAAGTAAATCAGCAATGGCAAATCAAAACAGTTAGATAA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (206-446)

• Domain of unknown function (DUF4131) (DUF4131) (27-171)

• Metallo-beta-lactamase superfamily (Lactamase_B) (483-689)

3D structure

• AlphaFold DB: A0A1E7G5C4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Lactococcus lactis subsp. cremoris KW2	98.37	100	0.984
comEC/celB	Streptococcus mitis SK321	45.676	100	0.459
comEC/celB	Streptococcus pneumoniae TIGR4	44.595	100	0.448
comEC/celB	Streptococcus mitis NCTC 12261	44.655	100	0.448
comEC/celB	Streptococcus pneumoniae Rx1	43.919	100	0.442
comEC/celB	Streptococcus pneumoniae D39	43.919	100	0.442
comEC/celB	Streptococcus pneumoniae R6	43.919	100	0.442