Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYF   Type   Machinery gene
Locus tag   VKP38_RS00680 Genome accession   NZ_CP142352
Coordinates   107164..107598 (+) Length   144 a.a.
NCBI ID   WP_002992738.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain 2907-97     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 102164..112598
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VKP38_RS00650 (VKP38_00650) - 103833..104198 (+) 366 WP_002986560.1 DUF1033 family protein -
  VKP38_RS00655 (VKP38_00655) comYA 104291..105229 (+) 939 WP_023079010.1 competence type IV pilus ATPase ComGA Machinery gene
  VKP38_RS00660 (VKP38_00660) comYB 105165..106199 (+) 1035 WP_011054115.1 competence type IV pilus assembly protein ComGB Machinery gene
  VKP38_RS00665 (VKP38_00665) comYC 106201..106527 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  VKP38_RS00670 (VKP38_00670) comGD 106502..106930 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD -
  VKP38_RS00675 (VKP38_00675) comGE 106887..107171 (+) 285 WP_032465969.1 competence type IV pilus minor pilin ComGE -
  VKP38_RS00680 (VKP38_00680) comYF 107164..107598 (+) 435 WP_002992738.1 competence type IV pilus minor pilin ComGF Machinery gene
  VKP38_RS00685 (VKP38_00685) comGG 107582..107908 (+) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  VKP38_RS00690 (VKP38_00690) comYH 108006..108959 (+) 954 WP_023610878.1 class I SAM-dependent methyltransferase Machinery gene
  VKP38_RS00695 (VKP38_00695) - 109018..110214 (+) 1197 WP_010921803.1 acetate kinase -
  VKP38_RS00700 (VKP38_00700) - 110401..110709 (+) 309 Protein_91 hypothetical protein -
  VKP38_RS00705 (VKP38_00705) proC 110792..111562 (-) 771 WP_023610882.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 144 a.a.        Molecular weight: 16645.27 Da        Isoelectric Point: 10.2526

>NTDB_id=925082 VKP38_RS00680 WP_002992738.1 107164..107598(+) (comYF) [Streptococcus pyogenes strain 2907-97]
MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTQTLLKRSHYLARHDQDNWLLFSHQLREELSGARFYKVADNKLYVEK
GKKVLAFGQFKSHDFRKSASNGKGYQPMLFGISRSHIHIEQSQICITLKWKSGLERTFYYAFQD

Nucleotide


Download         Length: 435 bp        

>NTDB_id=925082 VKP38_RS00680 WP_002992738.1 107164..107598(+) (comYF) [Streptococcus pyogenes strain 2907-97]
TTGAGTAAACAATTAAGTAACATAAAAGCTTTTACCCTTCTAGAGGCGTTAATAGCCTTACTCGTGATATCAGGGTCTTT
ATTGGTTTATCAAGGTTTGACCCAAACCCTCCTTAAACGTAGCCATTATCTAGCCCGTCATGATCAAGACAATTGGCTCT
TATTTTCTCATCAATTGCGAGAGGAGTTAAGTGGAGCAAGATTTTACAAAGTAGCTGATAATAAACTATACGTTGAAAAA
GGAAAGAAAGTACTAGCTTTTGGCCAATTTAAAAGTCATGATTTCCGAAAATCAGCTAGTAATGGAAAAGGGTATCAACC
CATGTTATTTGGAATATCACGTAGTCATATTCACATAGAGCAGTCACAGATTTGCATTACTTTAAAGTGGAAAAGTGGGT
TAGAAAGGACTTTTTATTATGCCTTTCAAGACTAA

Domains

Predicted by InterproScan.

Putative Competence protein ComGF (ComGF)

(41-135)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYF Streptococcus mutans UA140

51.079

96.528

0.493
  comYF Streptococcus mutans UA159

50.36

96.528

0.486
  comGF Lactococcus lactis subsp. cremoris KW2

46.715

95.139

0.444
  comGF/cglF Streptococcus mitis NCTC 12261

44.776

93.056

0.417
  comGF/cglF Streptococcus pneumoniae Rx1

43.609

92.361

0.403
  comGF/cglF Streptococcus pneumoniae D39

43.609

92.361

0.403
  comGF/cglF Streptococcus pneumoniae R6

43.609

92.361

0.403
  comGF/cglF Streptococcus pneumoniae TIGR4

43.609

92.361

0.403
  comGF/cglF Streptococcus mitis SK321

42.857

92.361

0.396