Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   VKP35_RS01445 Genome accession   NZ_CP142349
Coordinates   261902..262663 (+) Length   253 a.a.
NCBI ID   WP_002986029.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain 11RS100     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 256902..267663
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VKP35_RS01430 (VKP35_01430) - 257852..258871 (+) 1020 WP_326623030.1 IS30-like element IS1239 family transposase -
  VKP35_RS01435 (VKP35_01435) - 258926..260851 (+) 1926 WP_002986033.1 DUF2207 domain-containing protein -
  VKP35_RS01440 (VKP35_01440) - 260917..261756 (+) 840 WP_002986031.1 undecaprenyl-diphosphate phosphatase -
  VKP35_RS01445 (VKP35_01445) mecA 261902..262663 (+) 762 WP_002986029.1 adaptor protein MecA Regulator
  VKP35_RS01450 (VKP35_01450) - 262670..263839 (+) 1170 WP_002986027.1 glycosyltransferase family 4 protein -
  VKP35_RS01455 (VKP35_01455) sufC 263961..264731 (+) 771 WP_326623033.1 Fe-S cluster assembly ATPase SufC -
  VKP35_RS01460 (VKP35_01460) sufD 264826..266088 (+) 1263 WP_111713147.1 Fe-S cluster assembly protein SufD -
  VKP35_RS01465 (VKP35_01465) - 266119..267345 (+) 1227 WP_111713148.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 253 a.a.        Molecular weight: 29051.72 Da        Isoelectric Point: 4.1622

>NTDB_id=924925 VKP35_RS01445 WP_002986029.1 261902..262663(+) (mecA) [Streptococcus pyogenes strain 11RS100]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEI
NKDINLEDLAEFGDMSQMTPEDFFKSLEQSMREKGDVKAHEKLEKIEEIMEDVVEATLANQSEAADPSTNHESEPLDYVH
YVLDFSTITEAVAFAKTIDFSIEASELYKGSNCYHMTILLDVQQQPSYFANVMYARLIEHANPGSKTRAYLQEHGLQLML
DGAVEQLQKIELG

Nucleotide


Download         Length: 762 bp        

>NTDB_id=924925 VKP35_RS01445 WP_002986029.1 261902..262663(+) (mecA) [Streptococcus pyogenes strain 11RS100]
ATGGAAATGAAACAAATTAGCGAGACAACGCTAAAAATAACAATTAGTATGGACGATTTAGAAGAAAGAGGAATGGAGTT
GAAAGATTTCTTGATTCCTCAAGAAAAAACAGAAGAGTTTTTCTATTCTGTGATGGATGAACTCGATCTTCCAGATAATT
TTAAAGATAGTGGTATGCTTAGCTTTCGAGTGACTCCACGCAAGGACCGTCTAGATGTTTTTGTTACCAAATCTGAGATA
AATAAAGATATTAATCTTGAAGATTTAGCAGAGTTTGGTGATATGTCCCAAATGACTCCGGAAGATTTTTTCAAGAGCTT
GGAGCAATCCATGCGTGAAAAGGGAGATGTCAAAGCTCATGAAAAATTGGAAAAAATTGAAGAGATAATGGAAGATGTTG
TTGAAGCCACTCTAGCTAATCAGTCTGAGGCGGCTGATCCATCAACTAATCATGAGTCAGAACCTTTAGACTATGTCCAT
TATGTATTGGATTTTTCAACGATTACAGAGGCAGTGGCTTTTGCTAAAACGATTGATTTTTCGATAGAAGCTTCAGAGTT
ATATAAGGGGAGCAACTGCTACCATATGACTATTTTATTAGATGTTCAGCAACAACCATCTTATTTTGCGAATGTCATGT
ATGCGAGATTGATTGAGCATGCAAACCCTGGATCAAAAACAAGAGCTTATTTACAAGAGCATGGCTTACAATTGATGCTT
GATGGTGCTGTTGAGCAATTACAAAAGATTGAGTTGGGATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

63.2

98.814

0.625
  mecA Streptococcus thermophilus LMD-9

56.225

98.419

0.553
  mecA Streptococcus thermophilus LMG 18311

55.422

98.419

0.545
  mecA Streptococcus pneumoniae Rx1

48.235

100

0.486
  mecA Streptococcus pneumoniae D39

48.235

100

0.486
  mecA Streptococcus pneumoniae R6

48.235

100

0.486
  mecA Streptococcus pneumoniae TIGR4

48.235

100

0.486