Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   VKP35_RS00330 Genome accession   NZ_CP142349
Coordinates   53337..54248 (+) Length   303 a.a.
NCBI ID   WP_002986681.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain 11RS100     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 48337..59248
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VKP35_RS00310 (VKP35_00310) purE 48630..49121 (+) 492 WP_002987716.1 5-(carboxyamino)imidazole ribonucleotide mutase -
  VKP35_RS00315 (VKP35_00315) purK 49108..50181 (+) 1074 WP_172452778.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  VKP35_RS00320 (VKP35_00320) - 50202..51542 (+) 1341 WP_002987721.1 hypothetical protein -
  VKP35_RS00325 (VKP35_00325) purB 51911..53203 (+) 1293 WP_111713105.1 adenylosuccinate lyase -
  VKP35_RS00330 (VKP35_00330) comR 53337..54248 (+) 912 WP_002986681.1 transcriptional regulator Rgg4/ComR Regulator
  VKP35_RS09425 comS 54332..54427 (+) 96 WP_198462994.1 quorum-sensing system DWW-type pheromone Regulator
  VKP35_RS00335 (VKP35_00335) ruvB 54474..55472 (+) 999 WP_002986679.1 Holliday junction branch migration DNA helicase RuvB -
  VKP35_RS00340 (VKP35_00340) - 55610..56047 (+) 438 WP_002986675.1 low molecular weight protein-tyrosine-phosphatase -
  VKP35_RS00345 (VKP35_00345) - 56070..56471 (+) 402 WP_002986671.1 MORN repeat-containing protein -
  VKP35_RS00350 (VKP35_00350) - 56468..58243 (+) 1776 WP_136119346.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 303 a.a.        Molecular weight: 35757.27 Da        Isoelectric Point: 4.4858

>NTDB_id=924914 VKP35_RS00330 WP_002986681.1 53337..54248(+) (comR) [Streptococcus pyogenes strain 11RS100]
MLEHFGGKVKVLRLEKRISREDLCGDESELSVRQLARIELGQSIPSLSKVIFIAKALNVSVGYLTDGADLELPKRYKELK
YLILRTPTYMDDGKLQVREEQFDEIFEDYYDKLPEEEKIIIDCLQATLDTLLSENTNFGIDLLQEYFNQIKTKVRFRQND
LILLELYLAYLDIEGMDGQYSDKIFYDSLLDNLSEQFEQFELDELFIVNKIIIDISSLSLKNNRLDNLEKAIEMSQKIMA
KIQDWNRMPILKLIEWKYFLIKQKDIIKAEQSFMKACLFAQMTADQYLENKLIQEWEKDVKSY

Nucleotide


Download         Length: 912 bp        

>NTDB_id=924914 VKP35_RS00330 WP_002986681.1 53337..54248(+) (comR) [Streptococcus pyogenes strain 11RS100]
ATGTTAGAACATTTTGGTGGAAAAGTAAAAGTGTTAAGACTTGAAAAGAGGATTAGTCGCGAGGACTTGTGTGGGGATGA
GTCTGAACTTTCTGTTCGTCAATTAGCACGGATAGAACTAGGTCAATCCATACCAAGTTTAAGTAAGGTTATTTTTATTG
CAAAAGCCTTAAACGTTAGTGTCGGTTACTTAACTGATGGTGCTGATTTAGAACTACCTAAGCGTTACAAAGAATTAAAA
TACCTTATCTTAAGGACACCAACTTACATGGATGATGGAAAATTACAAGTACGAGAAGAGCAGTTTGATGAAATTTTTGA
GGATTATTATGATAAATTACCAGAGGAAGAGAAAATAATCATTGATTGTTTACAGGCAACTTTAGATACTTTATTGAGTG
AGAATACTAACTTTGGCATTGACTTACTTCAAGAATATTTTAATCAAATAAAGACTAAGGTACGCTTTAGGCAAAATGAT
TTAATACTTCTAGAATTATATTTAGCTTATCTTGATATTGAGGGAATGGATGGACAATATTCAGATAAGATTTTTTATGA
TTCTTTATTAGATAATCTATCAGAACAATTTGAACAATTTGAATTAGATGAATTATTTATAGTTAATAAGATTATCATTG
ATATTTCATCACTAAGCTTAAAAAATAACCGACTTGATAATTTAGAAAAAGCGATTGAAATGAGTCAAAAAATTATGGCG
AAAATTCAAGATTGGAATAGAATGCCTATTTTAAAACTAATAGAATGGAAATATTTTTTAATCAAACAAAAAGATATAAT
AAAAGCAGAACAATCATTTATGAAGGCATGTTTGTTCGCCCAAATGACAGCTGATCAGTATTTGGAAAACAAGTTAATTC
AAGAGTGGGAAAAAGATGTTAAAAGTTATTAA

Domains

Predicted by InterproScan.

Helix-turn-helix (HTH_3)

(12-64)

ComR tetratricopeptide (ComR_TPR)

(73-296)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS8232

100

100

1
  comR Streptococcus pyogenes MGAS315

58.472

99.34

0.581
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

51.37

96.37

0.495
  comR Streptococcus mutans UA159

46.358

99.67

0.462