Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   VOI49_RS01880 Genome accession   NZ_CP142018
Coordinates   344856..345617 (+) Length   253 a.a.
NCBI ID   WP_115246692.1    Uniprot ID   A0A380JY53
Organism   Streptococcus dysgalactiae strain lu24     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 339856..350617
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VOI49_RS01865 - 340121..341689 (-) 1569 WP_226317301.1 ABC transporter substrate-binding protein/permease -
  VOI49_RS01870 - 341887..343807 (+) 1921 Protein_313 DUF2207 family protein -
  VOI49_RS01875 - 343874..344713 (+) 840 WP_226314038.1 undecaprenyl-diphosphate phosphatase -
  VOI49_RS01880 mecA 344856..345617 (+) 762 WP_115246692.1 adaptor protein MecA Regulator
  VOI49_RS01885 - 345624..346793 (+) 1170 WP_226314037.1 glycosyltransferase family 4 protein -
  VOI49_RS01890 sufC 346906..347676 (+) 771 WP_115252601.1 Fe-S cluster assembly ATPase SufC -
  VOI49_RS01895 sufD 347773..349035 (+) 1263 WP_226314036.1 Fe-S cluster assembly protein SufD -
  VOI49_RS01900 - 349066..350292 (+) 1227 WP_226314035.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 253 a.a.        Molecular weight: 29183.85 Da        Isoelectric Point: 4.0916

>NTDB_id=921001 VOI49_RS01880 WP_115246692.1 344856..345617(+) (mecA) [Streptococcus dysgalactiae strain lu24]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEL
NKDLNLEDLADLGDISQMTPEDFFKSLEQSMREKGDVNAHEKLEKIEEMMEDVVEATLVSQTEETAEEVEQEPEPLDYVH
YVLDFATLSEAVAFSRTIDFPVEASELYKGDSRYHMTILLDVQQQPSYFANVMYARLIEHASPGTKTRAYLQEHGVQLIL
DGAVEQLRKIELG

Nucleotide


Download         Length: 762 bp        

>NTDB_id=921001 VOI49_RS01880 WP_115246692.1 344856..345617(+) (mecA) [Streptococcus dysgalactiae strain lu24]
ATGGAAATGAAACAAATTAGTGAGACAACGCTAAAAATAACAATTAGTATGGATGATTTAGAAGAAAGAGGGATGGAATT
AAAAGATTTTCTCATTCCTCAAGAAAAAACGGAAGAGTTCTTCTACTCTGTCATGGATGAGTTGGATCTACCAGACAATT
TCAAAGATAGTGGCATGCTTAGCTTTCGTGTGACCCCTAGAAAAGACCGTTTGGATGTCTTTGTAACCAAGTCTGAACTC
AATAAGGACCTTAATCTTGAGGATTTAGCTGATTTGGGAGACATCTCTCAAATGACTCCTGAAGACTTTTTCAAGAGCTT
AGAACAATCTATGCGAGAAAAAGGGGATGTAAATGCCCATGAGAAACTGGAAAAAATTGAAGAAATGATGGAAGACGTTG
TTGAAGCAACTCTAGTTAGTCAAACGGAAGAGACCGCTGAGGAAGTGGAACAAGAACCAGAGCCGTTAGATTACGTGCAT
TATGTTTTGGACTTTGCAACACTTTCAGAGGCCGTCGCTTTTTCTCGGACAATTGATTTTCCTGTTGAAGCTTCAGAATT
GTATAAAGGTGACAGCCGTTATCATATGACGATTTTATTAGATGTTCAGCAACAACCATCTTATTTTGCCAATGTGATGT
ATGCAAGACTGATTGAGCATGCTAGTCCTGGAACAAAAACAAGAGCTTACTTACAAGAGCATGGCGTACAATTAATTCTG
GATGGAGCTGTTGAGCAATTACGAAAGATTGAGTTGGGATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A380JY53

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

64.4

98.814

0.636
  mecA Streptococcus thermophilus LMD-9

57.028

98.419

0.561
  mecA Streptococcus thermophilus LMG 18311

56.225

98.419

0.553
  mecA Streptococcus pneumoniae Rx1

47.843

100

0.482
  mecA Streptococcus pneumoniae D39

47.843

100

0.482
  mecA Streptococcus pneumoniae R6

47.843

100

0.482
  mecA Streptococcus pneumoniae TIGR4

47.843

100

0.482