Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   VF946_RS02185 Genome accession   NZ_CP141824
Coordinates   430021..430665 (-) Length   214 a.a.
NCBI ID   WP_012027589.1    Uniprot ID   A0A0M9FEX3
Organism   Streptococcus suis strain HB18     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 425021..435665
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VF946_RS02170 - 425793..426320 (+) 528 WP_012027591.1 VanZ family protein -
  VF946_RS02175 nadE 427616..428440 (-) 825 WP_238716831.1 ammonia-dependent NAD(+) synthetase -
  VF946_RS02180 - 428453..429913 (-) 1461 WP_012027590.1 nicotinate phosphoribosyltransferase -
  VF946_RS02185 cclA/cilC 430021..430665 (-) 645 WP_012027589.1 prepilin peptidase Machinery gene
  VF946_RS02190 - 430787..431341 (+) 555 WP_004194627.1 tRNA (mnm(5)s(2)U34)-methyltransferase -
  VF946_RS02195 - 431357..432136 (-) 780 WP_012027588.1 ABC transporter ATP-binding protein -
  VF946_RS02200 - 432269..433606 (+) 1338 WP_074389850.1 hemolysin family protein -
  VF946_RS02205 pflA 433727..434518 (+) 792 WP_238716830.1 pyruvate formate-lyase-activating protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24215.33 Da        Isoelectric Point: 8.4760

>NTDB_id=919749 VF946_RS02185 WP_012027589.1 430021..430665(-) (cclA/cilC) [Streptococcus suis strain HB18]
MKTIILFFLGASIGSFLGLVIDRFPEQSIIAPSSHCNACKRRLKAWDLIPVLSQLSTKSKCRYCKAKIPYWYLGLEFLAG
LVVLLCHFQVLNLTETILILAGLVLTIYDIKHQEYPFAVWLIFTFIALILSQLNWLFCGFLLLAYLTEKWQINIGSGDFL
YLASLALICGFTELLWIIQISSLLGLLVFAIFKPKSIPYVPLLFLSSIPIILCT

Nucleotide


Download         Length: 645 bp        

>NTDB_id=919749 VF946_RS02185 WP_012027589.1 430021..430665(-) (cclA/cilC) [Streptococcus suis strain HB18]
ATGAAGACAATTATCCTATTTTTCCTTGGAGCTTCTATCGGCTCCTTCTTGGGATTGGTCATCGACCGTTTCCCTGAACA
GTCCATTATCGCCCCCTCTAGTCACTGCAATGCCTGCAAACGACGGCTCAAGGCCTGGGACTTAATTCCAGTCCTATCCC
AGCTTTCGACAAAATCCAAATGCCGTTACTGCAAGGCGAAGATACCTTATTGGTATCTGGGATTGGAATTCTTAGCCGGT
CTAGTTGTCCTGCTCTGCCATTTTCAAGTCCTAAACCTAACCGAAACCATTCTCATCTTGGCAGGACTAGTTTTGACCAT
TTACGACATCAAGCATCAGGAATATCCTTTTGCTGTCTGGCTCATTTTTACTTTTATAGCTCTGATACTCTCCCAGCTCA
ACTGGCTTTTCTGTGGCTTTTTACTCTTGGCCTATCTGACTGAAAAATGGCAAATCAATATTGGTTCTGGTGACTTTCTC
TATCTGGCAAGTTTGGCCTTAATATGTGGATTTACAGAACTCCTCTGGATTATCCAGATTAGTTCCCTCCTAGGGCTTCT
TGTCTTCGCCATTTTCAAACCCAAGTCTATTCCCTACGTACCACTCCTATTTCTTTCAAGTATTCCTATCATTCTGTGCA
CCTAA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(9-88)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0M9FEX3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus mitis SK321

49.528

99.065

0.491
  cclA/cilC Streptococcus pneumoniae Rx1

49.029

96.262

0.472
  cclA/cilC Streptococcus pneumoniae D39

49.029

96.262

0.472
  cclA/cilC Streptococcus pneumoniae R6

49.029

96.262

0.472
  cclA/cilC Streptococcus pneumoniae TIGR4

47.17

99.065

0.467
  cclA/cilC Streptococcus mitis NCTC 12261

45.755

99.065

0.453