Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   VF946_RS01910 Genome accession   NZ_CP141824
Coordinates   381474..382163 (+) Length   229 a.a.
NCBI ID   WP_012027645.1    Uniprot ID   -
Organism   Streptococcus suis strain HB18     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 376474..387163
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VF946_RS01885 - 376803..378146 (+) 1344 WP_024380515.1 DEAD/DEAH box helicase -
  VF946_RS01890 - 378164..378388 (+) 225 WP_002936682.1 DUF4059 family protein -
  VF946_RS01895 trxB 378402..379319 (+) 918 WP_002942687.1 thioredoxin-disulfide reductase -
  VF946_RS01900 - 379329..379868 (+) 540 WP_024385904.1 YceD family protein -
  VF946_RS01905 gndA 379965..381392 (+) 1428 WP_002942698.1 NADP-dependent phosphogluconate dehydrogenase -
  VF946_RS01910 covR 381474..382163 (+) 690 WP_012027645.1 DNA-binding response regulator Regulator
  VF946_RS01915 - 382253..383383 (+) 1131 WP_012027644.1 AI-2E family transporter -
  VF946_RS01920 nrdR 383455..383946 (+) 492 WP_002938341.1 transcriptional regulator NrdR -
  VF946_RS01925 - 383933..385084 (+) 1152 WP_024386752.1 replication initiation/membrane attachment protein -
  VF946_RS01930 dnaI 385084..385983 (+) 900 WP_002938337.1 primosomal protein DnaI -
  VF946_RS01935 - 385980..386693 (+) 714 Protein_344 nitroreductase family protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26255.14 Da        Isoelectric Point: 5.3968

>NTDB_id=919747 VF946_RS01910 WP_012027645.1 381474..382163(+) (covR) [Streptococcus suis strain HB18]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYASTGKEAMSLAHETDFDLILMSFQLSDMSSKELATELLAIKPATVMIVV
VEPTEVSQYGEEVLSYAVSYVVKPFVISDLVEQISAIFRGRDFIDNNCKQVHMHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPHQDSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=919747 VF946_RS01910 WP_012027645.1 381474..382163(+) (covR) [Streptococcus suis strain HB18]
ATGGCTAAGAAAATTTTGATTGCTGGTAAAGAACGCAATCTCTCGCATTTTGTTTCCATGGAATTGCAGAAAAAAGACTA
TCTTGTTGATTATGCATCGACAGGGAAAGAGGCTATGTCCTTGGCACATGAAACGGATTTTGACTTGATTCTGATGAGTT
TTCAGCTTTCAGACATGTCCAGCAAGGAATTGGCTACAGAACTATTAGCGATAAAACCAGCCACGGTCATGATTGTGGTA
GTTGAGCCGACTGAAGTTAGTCAATATGGGGAGGAAGTCCTCTCTTATGCTGTTTCCTACGTAGTGAAGCCCTTTGTCAT
CAGTGATTTAGTGGAGCAAATCTCTGCGATTTTTCGTGGTCGTGATTTTATTGACAATAACTGTAAACAGGTTCACATGC
ATGCGGCCTATCGTGATTTGAAGGTTGATTTTCAAAATCGAACAGTGACTCGAGGTGATGAATTGATTAATTTGACCCGC
CGAGAGTATGATCTGTTGGCGACCTTAATGAATAGCCCAGAGCCTGTTAGTCGAGAACAACTTCTTGAGCGTGTTTGGAA
ATATGAAGCGGCTTCTGAGACCAATGTCGTCGATGTATATATTCGCTATCTACGTGGTAAACTGGATTTGCCACATCAAG
ATTCATATATAAAAACAGTTCGTGGTGTCGGATATGCCATGCGCGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.619

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.949

100

0.432