Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   VNN28_RS04125 Genome accession   NZ_CP141725
Coordinates   838547..839764 (-) Length   405 a.a.
NCBI ID   WP_338997927.1    Uniprot ID   -
Organism   Lactococcus formosensis strain M03102409 EE5d7     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 833547..844764
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VNN28_RS04100 (VNN28_04100) - 833843..834592 (+) 750 WP_338997922.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  VNN28_RS04105 (VNN28_04105) - 834751..835800 (+) 1050 WP_017369973.1 BMP family protein -
  VNN28_RS04110 (VNN28_04110) - 835830..836054 (-) 225 WP_017369972.1 DUF1797 family protein -
  VNN28_RS04115 (VNN28_04115) - 836105..837439 (-) 1335 WP_338997925.1 glycosyltransferase family 4 protein -
  VNN28_RS04120 (VNN28_04120) - 837452..838450 (-) 999 WP_096368976.1 glycosyltransferase family 4 protein -
  VNN28_RS04125 (VNN28_04125) htrA 838547..839764 (-) 1218 WP_338997927.1 trypsin-like peptidase domain-containing protein Regulator
  VNN28_RS04130 (VNN28_04130) rlmH 840068..840547 (+) 480 WP_096368977.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  VNN28_RS04135 (VNN28_04135) - 840544..841191 (+) 648 WP_270741305.1 DNA alkylation repair protein -
  VNN28_RS04140 (VNN28_04140) yajC 841266..841598 (+) 333 WP_017369966.1 preprotein translocase subunit YajC -
  VNN28_RS04145 (VNN28_04145) - 841797..842534 (+) 738 WP_017369965.1 isoprenyl transferase -
  VNN28_RS04150 (VNN28_04150) - 842531..843325 (+) 795 WP_017369964.1 phosphatidate cytidylyltransferase -
  VNN28_RS04155 (VNN28_04155) eeP 843502..844749 (+) 1248 WP_213497234.1 RIP metalloprotease RseP Regulator

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 41849.66 Da        Isoelectric Point: 4.8808

>NTDB_id=918996 VNN28_RS04125 WP_338997927.1 838547..839764(-) (htrA) [Lactococcus formosensis strain M03102409 EE5d7]
MAKKNIASLLITGVAGGAIALGGSAIYQNMTNTPSSNNTSDNSVSTVNVQVNTDTTKAIKKISNTVVSVLNYQKSSSSND
FEKIFGGGDTSSNESNSPQLSGEGSGVIYKKDGNTAYIVTNYHVIEGASSLEVLMAGGQKVTAEVVGSDAYSDLAVLKID
AKYVQETATFGNSDKLTVGKPAIAVGSPLGSEYANSATEGIVSSLNRNVTLQNSQGQTINVNAIQTDAAINPGNSGGALI
NIQGQVIGITSSKITSTPSGTSSSGVSVEGMGFAIPANDVVNIINKLEKDGKVIRPALGVQMVNLSSLSQNMLASLNLPE
DVTNGVAVAEVQSGMPAAKAGLKQGDVIVKINDDEITSSVNLQSTLYKSSIGDTIKVTYYRDGKQATTNIKLDKTSSDIN
FDKQN

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=918996 VNN28_RS04125 WP_338997927.1 838547..839764(-) (htrA) [Lactococcus formosensis strain M03102409 EE5d7]
ATGGCAAAAAAAAATATCGCCTCATTACTTATTACGGGCGTAGCCGGAGGTGCTATCGCTCTTGGGGGTAGTGCTATCTA
CCAAAATATGACTAACACGCCGTCATCTAATAATACTTCGGACAATTCTGTAAGTACAGTTAACGTACAAGTCAATACAG
ATACAACCAAAGCAATCAAGAAAATTTCAAACACTGTTGTTTCCGTACTTAATTACCAAAAATCGTCTTCAAGCAACGAC
TTTGAAAAGATTTTCGGCGGAGGCGACACAAGCAGCAATGAGAGTAACTCACCACAGCTATCTGGAGAAGGTTCTGGGGT
TATCTATAAAAAGGACGGCAATACCGCATACATCGTAACCAACTATCACGTTATTGAAGGTGCGTCTTCCTTAGAAGTTC
TCATGGCTGGTGGTCAAAAAGTAACTGCCGAAGTTGTTGGTTCCGATGCTTATTCGGATTTAGCTGTCCTCAAAATTGAT
GCCAAGTATGTCCAAGAAACAGCAACGTTCGGCAACTCTGACAAACTTACTGTTGGTAAACCTGCTATCGCCGTTGGTTC
TCCTCTTGGAAGTGAGTATGCTAACTCAGCAACAGAAGGTATTGTTTCTAGTCTTAATCGCAATGTTACATTGCAAAACA
GCCAAGGCCAAACCATTAATGTTAATGCTATTCAAACAGATGCAGCAATAAACCCCGGGAACTCTGGCGGTGCACTCATC
AATATACAAGGACAAGTCATCGGGATCACCTCAAGTAAAATTACCTCAACACCAAGCGGAACAAGCAGCAGCGGTGTCTC
TGTAGAAGGCATGGGGTTTGCGATTCCAGCCAATGATGTCGTCAATATTATCAATAAATTGGAAAAAGATGGCAAAGTTA
TTCGACCTGCTCTGGGTGTGCAAATGGTTAACCTATCAAGTCTTTCACAAAATATGTTGGCTTCACTCAACCTTCCTGAA
GACGTGACGAACGGTGTTGCTGTCGCTGAAGTTCAATCAGGAATGCCTGCTGCCAAAGCTGGACTCAAGCAAGGCGACGT
TATTGTCAAAATCAATGATGACGAAATCACTTCAAGTGTTAACCTTCAAAGCACACTTTATAAATCTTCAATTGGTGATA
CGATTAAGGTAACTTATTATCGTGACGGAAAACAAGCTACTACAAATATCAAGTTAGATAAAACAAGTAGTGATATCAAT
TTTGACAAGCAAAATTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(296-392)

Trypsin-like peptidase domain (Trypsin_2)

(104-249)

Peptidase family M50 (Peptidase_M50)

(266-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

56.614

93.333

0.528
  htrA Streptococcus mitis NCTC 12261

53.383

98.519

0.526
  htrA Streptococcus pneumoniae Rx1

53.133

98.519

0.523
  htrA Streptococcus pneumoniae D39

53.133

98.519

0.523
  htrA Streptococcus pneumoniae R6

53.133

98.519

0.523
  htrA Streptococcus pneumoniae TIGR4

53.133

98.519

0.523
  htrA Streptococcus gordonii str. Challis substr. CH1

53.964

96.543

0.521