Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   VNN48_RS08985 Genome accession   NZ_CP141723
Coordinates   1840164..1840859 (+) Length   231 a.a.
NCBI ID   WP_017368870.1    Uniprot ID   A0A9Q8Y2F9
Organism   Lactococcus formosensis strain PAQ-208     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1835164..1845859
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VNN48_RS08960 (VNN48_08955) - 1835387..1836088 (+) 702 WP_017368868.1 DeoR/GlpR family DNA-binding transcription regulator -
  VNN48_RS08965 (VNN48_08960) pfkB 1836085..1837002 (+) 918 WP_279359203.1 1-phosphofructokinase -
  VNN48_RS08970 (VNN48_08965) - 1837036..1838940 (+) 1905 WP_213432793.1 fructose-specific PTS transporter subunit EIIC -
  VNN48_RS08975 (VNN48_08970) - 1839052..1839294 (+) 243 WP_003135050.1 type B 50S ribosomal protein L31 -
  VNN48_RS08980 (VNN48_08975) - 1839512..1840063 (+) 552 WP_279359205.1 DUF177 domain-containing protein -
  VNN48_RS08985 (VNN48_08980) covR 1840164..1840859 (+) 696 WP_017368870.1 response regulator transcription factor Regulator
  VNN48_RS08990 (VNN48_08985) covS 1840947..1842437 (+) 1491 WP_017368871.1 HAMP domain-containing histidine kinase Regulator
  VNN48_RS08995 (VNN48_08990) - 1842833..1844404 (+) 1572 WP_017368872.1 ABC transporter permease subunit -
  VNN48_RS09000 (VNN48_08995) - 1844405..1845142 (+) 738 WP_017368873.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 27023.75 Da        Isoelectric Point: 5.2713

>NTDB_id=918956 VNN48_RS08985 WP_017368870.1 1840164..1840859(+) (covR) [Lactococcus formosensis strain PAQ-208]
MNSSKRILIIEDDKNIARFVSLELEHEGYQTAVQDNGRKGLEEAMSKDYDLILLDLMLPELDGFEVARRLRREKDTHIIM
MTARDSTMDRVAGLDIGADDYITKPFAIEELLARVRSLFRREDHIHTVEKSDNTSFRDLVIDKTNRTVHRGKKVIDLTRR
EYDLLLTLMQNVGDVVTREYLVSEVWGYEEGTETNVVDVYIRYLRNKIDVEGRESYIQTVRGMGYVMRDRK

Nucleotide


Download         Length: 696 bp        

>NTDB_id=918956 VNN48_RS08985 WP_017368870.1 1840164..1840859(+) (covR) [Lactococcus formosensis strain PAQ-208]
ATGAATTCATCTAAACGTATTTTGATTATCGAAGACGATAAAAACATTGCGAGATTTGTTTCACTTGAGCTTGAACACGA
AGGGTACCAAACTGCGGTTCAAGACAATGGTCGTAAAGGTCTTGAAGAAGCGATGTCAAAAGATTATGATTTGATTTTGC
TCGACTTAATGCTCCCAGAGCTGGATGGCTTTGAAGTTGCACGACGCTTACGCCGTGAAAAAGATACACACATTATCATG
ATGACTGCACGTGATTCAACAATGGACCGTGTAGCAGGTCTTGATATTGGAGCGGATGATTATATTACAAAACCATTCGC
AATTGAAGAATTGTTAGCACGTGTGCGTTCACTCTTCCGTCGTGAAGATCATATCCATACTGTTGAAAAGTCAGACAACA
CTTCATTCCGTGACTTAGTAATTGATAAAACAAACCGCACAGTACACCGTGGTAAAAAAGTTATTGACCTTACGCGTCGT
GAATACGACTTACTCTTGACTTTGATGCAAAATGTGGGGGACGTCGTAACACGCGAATACTTGGTTTCTGAAGTATGGGG
TTACGAAGAAGGTACAGAAACAAACGTTGTTGATGTTTATATCCGTTACCTACGTAACAAGATTGATGTCGAAGGCCGTG
AAAGTTATATCCAAACTGTTCGTGGCATGGGCTATGTCATGCGTGACCGCAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(7-116)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Lactococcus lactis subsp. lactis strain DGCC12653

88.646

99.134

0.879
  covR Streptococcus salivarius strain HSISS4

66.81

100

0.671
  vicR Streptococcus mutans UA159

43.723

100

0.437
  micA Streptococcus pneumoniae Cp1015

42.424

100

0.424