Detailed information NTG0918957

Bioinformatically predicted

Overview

• Name: covS
• Type: Regulator
• Locus tag: VNN48_RS08990
• Genome accession: NZ_CP141723
• Coordinates: 1840947..1842437 (+)
• Length: 496 a.a.
• NCBI ID: WP_017368871.1
• Uniprot ID: A0A9X4P077
• Organism: Lactococcus formosensis strain PAQ-208
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1835947..1847437

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VNN48_RS08965 (VNN48_08960)	pfkB	1836085..1837002 (+)	918	WP_279359203.1	1-phosphofructokinase	-
VNN48_RS08970 (VNN48_08965)	-	1837036..1838940 (+)	1905	WP_213432793.1	fructose-specific PTS transporter subunit EIIC	-
VNN48_RS08975 (VNN48_08970)	-	1839052..1839294 (+)	243	WP_003135050.1	type B 50S ribosomal protein L31	-
VNN48_RS08980 (VNN48_08975)	-	1839512..1840063 (+)	552	WP_279359205.1	DUF177 domain-containing protein	-
VNN48_RS08985 (VNN48_08980)	covR	1840164..1840859 (+)	696	WP_017368870.1	response regulator transcription factor	Regulator
VNN48_RS08990 (VNN48_08985)	covS	1840947..1842437 (+)	1491	WP_017368871.1	HAMP domain-containing histidine kinase	Regulator
VNN48_RS08995 (VNN48_08990)	-	1842833..1844404 (+)	1572	WP_017368872.1	ABC transporter permease subunit	-
VNN48_RS09000 (VNN48_08995)	-	1844405..1845142 (+)	738	WP_017368873.1	amino acid ABC transporter ATP-binding protein	-
VNN48_RS09005 (VNN48_09000)	murD	1845281..1846642 (+)	1362	WP_213432789.1	UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase	-

Sequence

Protein

• Length: 496 a.a.
• Molecular weight: 56906.83 Da
• Isoelectric Point: 4.9901

>NTDB_id=918957 VNN48_RS08990 WP_017368871.1 1840947..1842437(+) (covS) [Lactococcus formosensis strain PAQ-208]
MVKFFDSKKKKTESLPERKRSIMLRWAFANTIFCFITFTIFTVLVYQLTITTFINSEKEDMMRALNNVEQSLSQSANKLS
EENLANYLAYAKDYTASSQGRENELETLGSMIGSRKSFYVFDVGENLIYSTNSYGFPLRKDVGDSSQAVRTFGEYSGYLV
ERPVHSKKTGELIGYVQAFYDMSYYYSVRTKLLVALIILEIIALFIAQFVGYFMASRYIKPLERLHDAITTRANNLKADF
KPVVIQTGDEIEELATVYNDMMIKLNDYVDQQKRFVSDVSHELRTPLAVLDGHLNLLNRWGKNDPEVLEESLQASIEEVS
TMRTMLEEMLALARLESIDFQDEDLICDPTEVSNFLKKNFLLIHPDLKLTVENDLSSGRLAHIYPNHYEQGLKILIDNAI
KYSPEDRQEVKIHLEEDDEYIITTVEDRGYGISQEDLKHVFERFFRADKARNRDIGGTGLGLSIIQRIVENYEGDVSVTS
VVGEGSKFTLKIPKIK

Nucleotide

• Length: 1491 bp

>NTDB_id=918957 VNN48_RS08990 WP_017368871.1 1840947..1842437(+) (covS) [Lactococcus formosensis strain PAQ-208]
ATGGTAAAATTTTTTGATTCTAAGAAGAAAAAAACAGAAAGTCTTCCCGAGCGTAAGCGAAGCATCATGTTACGTTGGGC
ATTTGCAAATACGATTTTTTGTTTTATTACTTTCACTATTTTTACAGTATTGGTTTATCAACTAACGATAACTACTTTCA
TCAATTCTGAAAAAGAGGATATGATGAGGGCTTTAAATAATGTTGAACAAAGTCTGTCCCAATCGGCAAACAAACTGTCA
GAAGAAAATCTTGCGAATTATTTGGCTTATGCCAAAGACTACACAGCCTCCAGTCAGGGAAGAGAAAATGAACTTGAAAC
ACTAGGAAGTATGATTGGTTCAAGAAAGTCCTTTTATGTCTTTGATGTGGGTGAAAATCTGATCTACTCGACCAATTCGT
ATGGTTTTCCGCTAAGGAAAGATGTGGGTGATTCATCGCAAGCTGTACGTACATTTGGCGAATATTCTGGTTATTTGGTT
GAGCGACCTGTGCATTCTAAAAAAACGGGTGAACTGATCGGCTATGTACAGGCTTTTTATGATATGAGCTATTATTATAG
TGTGCGTACAAAGCTACTAGTTGCCTTGATTATCTTAGAAATTATAGCACTCTTTATTGCTCAGTTTGTTGGTTACTTTA
TGGCGAGCCGCTATATCAAGCCTTTGGAACGTTTGCACGATGCAATCACTACACGTGCCAATAATTTGAAGGCAGATTTC
AAACCTGTCGTTATTCAGACAGGGGATGAAATTGAAGAACTTGCAACAGTTTATAATGATATGATGATCAAGCTTAATGA
TTACGTTGATCAGCAGAAACGTTTTGTTTCCGATGTCAGTCATGAGTTACGGACGCCACTTGCAGTTTTGGATGGGCATT
TGAATCTCTTGAATCGTTGGGGGAAAAATGATCCTGAAGTGCTTGAGGAGTCTTTACAGGCCAGTATAGAAGAAGTTAGT
ACGATGAGAACGATGTTGGAAGAAATGCTCGCATTGGCACGTCTTGAAAGCATTGATTTTCAAGATGAAGACCTAATCTG
TGATCCGACAGAAGTTTCGAATTTTCTTAAGAAAAATTTTCTACTCATTCATCCTGATTTAAAGTTAACTGTTGAAAATG
ACTTGTCATCAGGAAGATTAGCACATATATACCCCAACCATTATGAGCAAGGTTTGAAAATATTGATCGATAATGCGATA
AAATACTCGCCTGAAGATCGTCAAGAAGTCAAGATACATCTTGAAGAAGATGATGAATATATCATTACAACTGTGGAGGA
CCGTGGTTATGGTATTAGCCAAGAAGATTTAAAACATGTATTTGAACGTTTCTTCCGTGCGGATAAAGCGCGAAATCGAG
ATATAGGAGGCACTGGGCTTGGGTTATCTATTATTCAACGTATAGTGGAGAACTATGAGGGGGATGTTAGCGTGACCTCC
GTTGTAGGAGAGGGTTCAAAATTTACTTTAAAAATTCCTAAGATTAAATAA

Domains

Predicted by InterproScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (272-337)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (389-494)

• HAMP domain (HAMP) (214-266)

• ArlS sensor domain (ArlS_N) (52-190)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
covS	Lactococcus lactis subsp. lactis strain DGCC12653	55.533	100	0.556