Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   VNN39_RS04125 Genome accession   NZ_CP141721
Coordinates   838557..839774 (-) Length   405 a.a.
NCBI ID   WP_339007251.1    Uniprot ID   -
Organism   Lactococcus formosensis strain M04020401 EE5e5     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 833557..844774
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VNN39_RS04100 (VNN39_04100) - 833853..834602 (+) 750 WP_213497223.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  VNN39_RS04105 (VNN39_04105) - 834761..835810 (+) 1050 WP_017369973.1 BMP family protein -
  VNN39_RS04110 (VNN39_04110) - 835840..836064 (-) 225 WP_017369972.1 DUF1797 family protein -
  VNN39_RS04115 (VNN39_04115) - 836115..837449 (-) 1335 WP_338997925.1 glycosyltransferase family 4 protein -
  VNN39_RS04120 (VNN39_04120) - 837462..838460 (-) 999 WP_096368976.1 glycosyltransferase family 4 protein -
  VNN39_RS04125 (VNN39_04125) htrA 838557..839774 (-) 1218 WP_339007251.1 S1C family serine protease Regulator
  VNN39_RS04130 (VNN39_04130) rlmH 840078..840557 (+) 480 WP_096368977.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  VNN39_RS04135 (VNN39_04135) - 840554..841201 (+) 648 WP_270741305.1 DNA alkylation repair protein -
  VNN39_RS04140 (VNN39_04140) yajC 841276..841608 (+) 333 WP_017369966.1 preprotein translocase subunit YajC -
  VNN39_RS04145 (VNN39_04145) - 841807..842544 (+) 738 WP_017369965.1 isoprenyl transferase -
  VNN39_RS04150 (VNN39_04150) - 842541..843335 (+) 795 WP_017369964.1 phosphatidate cytidylyltransferase -
  VNN39_RS04155 (VNN39_04155) eeP 843512..844759 (+) 1248 WP_213497234.1 RIP metalloprotease RseP Regulator

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 41875.74 Da        Isoelectric Point: 4.8808

>NTDB_id=918904 VNN39_RS04125 WP_339007251.1 838557..839774(-) (htrA) [Lactococcus formosensis strain M04020401 EE5e5]
MAKKNIASLLITGVAGGAIALGGSAIYQNMTNTPSSNNTSDNSVSTVNVQVNTDTTKAIKKISNTVVSVLNYQKSSSSND
FEKIFGGGDTSSNESNLPQLSGEGSGVIYKKDGNTAYIVTNYHVIEGASSLEVLMAGGQKVTAEVVGSDAYSDLAVLKID
AKYVQETATFGNSDKLTVGKPAIAVGSPLGSEYANSATEGIVSSLNRNVTLQNSQGQTINVNAIQTDAAINPGNSGGALI
NIQGQVIGITSSKITSTPSGTSSSGVSVEGMGFAIPANDVVNIINKLEKDGKVIRPALGVQMVNLSSLSQNMLASLNLPE
DVTNGVAVAEVQSGMPAAKAGLKQGDVIVKINDDEITSSVNLQSTLYKSSIGDTIKVTYYRDGKQATTNIKLDKTSSDIN
FDKQN

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=918904 VNN39_RS04125 WP_339007251.1 838557..839774(-) (htrA) [Lactococcus formosensis strain M04020401 EE5e5]
ATGGCAAAAAAAAATATCGCCTCATTACTTATTACGGGCGTAGCCGGAGGTGCTATCGCTCTTGGGGGTAGTGCTATCTA
CCAAAATATGACTAACACGCCGTCATCTAATAATACTTCGGACAATTCTGTAAGTACAGTTAACGTACAAGTCAATACAG
ATACAACCAAAGCAATCAAGAAAATTTCAAACACTGTTGTTTCCGTACTTAATTACCAAAAATCGTCTTCAAGCAACGAC
TTTGAAAAGATTTTCGGCGGAGGCGACACAAGCAGCAATGAGAGTAACTTACCACAGCTATCTGGAGAAGGTTCTGGGGT
TATCTATAAAAAGGACGGCAATACCGCATACATCGTAACCAACTATCACGTTATTGAAGGTGCGTCTTCCTTAGAAGTTC
TCATGGCTGGTGGTCAAAAAGTAACTGCCGAAGTTGTTGGTTCCGATGCTTATTCGGATTTAGCTGTCCTCAAAATTGAT
GCCAAGTATGTCCAAGAAACAGCAACGTTCGGCAACTCTGACAAACTTACTGTTGGTAAACCTGCTATCGCCGTTGGTTC
TCCTCTTGGAAGTGAGTATGCTAACTCAGCAACAGAAGGTATTGTTTCTAGTCTTAATCGCAATGTTACATTGCAAAACA
GCCAAGGCCAAACCATTAATGTTAATGCTATTCAAACAGATGCAGCAATAAACCCCGGGAACTCTGGCGGTGCACTCATC
AATATACAAGGACAAGTCATCGGGATCACCTCAAGTAAAATTACCTCAACACCAAGCGGAACAAGCAGCAGCGGTGTCTC
TGTAGAAGGCATGGGGTTTGCGATTCCAGCCAATGATGTCGTCAATATTATCAATAAATTGGAAAAAGATGGCAAAGTTA
TTCGACCTGCTCTGGGTGTGCAAATGGTTAACCTATCAAGTCTTTCACAAAATATGTTGGCTTCACTCAACCTTCCTGAA
GACGTGACGAACGGTGTTGCTGTCGCTGAAGTTCAATCAGGAATGCCTGCTGCCAAAGCTGGACTCAAGCAAGGCGACGT
TATTGTCAAAATCAATGATGACGAAATCACTTCAAGTGTTAACCTTCAAAGCACACTTTATAAATCTTCAATTGGTGATA
CGATTAAGGTAACTTATTATCGTGACGGAAAACAAGCTACTACAAATATCAAGTTAGATAAAACAAGTAGTGATATCAAT
TTTGACAAGCAAAATTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(296-392)

Trypsin-like peptidase domain (Trypsin_2)

(104-249)

Peptidase family M50 (Peptidase_M50)

(266-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

56.614

93.333

0.528
  htrA Streptococcus mitis NCTC 12261

53.133

98.519

0.523
  htrA Streptococcus gordonii str. Challis substr. CH1

53.964

96.543

0.521
  htrA Streptococcus pneumoniae TIGR4

52.882

98.519

0.521
  htrA Streptococcus pneumoniae D39

52.882

98.519

0.521
  htrA Streptococcus pneumoniae Rx1

52.882

98.519

0.521
  htrA Streptococcus pneumoniae R6

52.882

98.519

0.521