Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   VNN36_RS05030 Genome accession   NZ_CP141717
Coordinates   984010..985227 (-) Length   405 a.a.
NCBI ID   WP_003133516.1    Uniprot ID   A0A3D4RHV6
Organism   Lactococcus garvieae strain R22-8     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 979010..990227
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VNN36_RS05005 (VNN36_05005) - 979307..980055 (+) 749 Protein_956 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  VNN36_RS05010 (VNN36_05010) - 980216..981265 (+) 1050 WP_003133520.1 BMP family protein -
  VNN36_RS05015 (VNN36_05015) - 981292..981516 (-) 225 WP_003133519.1 DUF1797 family protein -
  VNN36_RS05020 (VNN36_05020) - 981567..982901 (-) 1335 WP_339014329.1 glycosyltransferase family 4 protein -
  VNN36_RS05025 (VNN36_05025) - 982914..983912 (-) 999 WP_003133517.1 glycosyltransferase family 4 protein -
  VNN36_RS05030 (VNN36_05030) htrA 984010..985227 (-) 1218 WP_003133516.1 trypsin-like peptidase domain-containing protein Regulator
  VNN36_RS05035 (VNN36_05035) rlmH 985531..986010 (+) 480 WP_003133515.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  VNN36_RS05040 (VNN36_05040) - 986007..986654 (+) 648 WP_339014331.1 DNA alkylation repair protein -
  VNN36_RS05045 (VNN36_05045) yajC 986729..987064 (+) 336 WP_014025468.1 preprotein translocase subunit YajC -
  VNN36_RS05050 (VNN36_05050) - 987265..988002 (+) 738 WP_339014333.1 isoprenyl transferase -
  VNN36_RS05055 (VNN36_05055) - 987999..988793 (+) 795 WP_003133509.1 phosphatidate cytidylyltransferase -
  VNN36_RS05060 (VNN36_05060) eeP 988969..990216 (+) 1248 WP_014025467.1 RIP metalloprotease RseP Regulator

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 41787.63 Da        Isoelectric Point: 4.8808

>NTDB_id=918768 VNN36_RS05030 WP_003133516.1 984010..985227(-) (htrA) [Lactococcus garvieae strain R22-8]
MAKKNIASLLITGVAGGAIALGGSAIYQNMTNTPSSNNTSDNSVSTVNVQVNTDTTKAIKKISNTVVSVLNYQKSSSSND
FEKIFGGGDTSSNDSNTPQLAGEGSGVIYKKDGNTAYIVTNYHVIEGASSLEVLMAGGQKVTAEVVGSDAYSDLAVLKID
AKYVKETATFGNSDKLTVGEPAIAVGSPLGSEYANSATEGIVSSLNRNVTLQNSQGQTINVNAIQTDAAINPGNSGGALI
NIQGQVIGITSSKITSTPSGTSGSGVSVEGMGFAIPANDVVNIINKLEKDGKVIRPALGVQMVNLSSLSQNMLASLNLPE
NVTNGVAIAEVQSGMPAAKAGLKQGDVIVKINDDEITSSVNLQSTLYKSSIGDTIKVTYYRDGKQATANIKLDKTSSDIN
FDKQN

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=918768 VNN36_RS05030 WP_003133516.1 984010..985227(-) (htrA) [Lactococcus garvieae strain R22-8]
ATGGCAAAGAAAAATATCGCCTCATTACTTATTACGGGCGTAGCCGGAGGTGCTATCGCTCTTGGAGGTAGTGCTATCTA
CCAAAACATGACCAATACACCATCATCTAATAACACTTCGGACAATTCTGTAAGTACGGTTAACGTCCAAGTCAATACAG
ATACAACCAAAGCAATCAAGAAAATTTCGAACACTGTTGTTTCCGTTCTTAATTACCAAAAATCGTCCTCAAGCAACGAT
TTTGAGAAGATTTTCGGTGGAGGCGATACAAGCAGCAATGACAGTAACACGCCACAGCTGGCTGGTGAAGGTTCTGGTGT
TATTTATAAAAAGGATGGCAATACAGCATACATCGTCACCAACTATCACGTGATTGAAGGTGCTTCTTCCTTAGAAGTTC
TCATGGCTGGCGGCCAAAAAGTTACTGCTGAAGTTGTTGGTTCTGATGCTTATTCTGATTTAGCTGTCCTCAAAATTGAT
GCTAAGTATGTCAAAGAAACAGCAACATTTGGTAACTCTGACAAACTTACTGTTGGTGAGCCCGCTATCGCGGTTGGTTC
TCCTCTTGGAAGTGAGTATGCCAACTCAGCAACGGAAGGGATTGTTTCAAGTCTTAATCGTAATGTTACGCTGCAAAACA
GCCAAGGCCAAACAATTAATGTGAACGCAATTCAAACCGATGCAGCAATTAACCCAGGTAACTCTGGTGGTGCACTCATA
AATATTCAGGGACAAGTCATCGGGATTACTTCAAGTAAAATTACCTCAACACCAAGCGGAACAAGCGGCAGTGGTGTCTC
TGTAGAAGGAATGGGCTTTGCGATACCAGCCAATGATGTGGTCAATATTATCAATAAGTTGGAAAAAGATGGCAAAGTTA
TTCGACCTGCTCTCGGTGTACAAATGGTCAACTTGTCAAGTCTTTCACAAAATATGTTGGCTTCACTTAATCTTCCTGAA
AATGTGACAAATGGTGTTGCTATCGCTGAAGTTCAATCAGGAATGCCTGCTGCCAAAGCTGGACTCAAGCAAGGTGACGT
TATTGTCAAAATCAATGATGACGAAATCACTTCAAGTGTGAACCTTCAAAGTACACTTTATAAGTCATCGATTGGTGATA
CGATTAAGGTAACTTATTATCGTGACGGAAAACAAGCTACTGCGAATATCAAGTTGGATAAAACAAGTAGTGATATCAAC
TTTGACAAACAAAATTAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(104-249)

PDZ domain (PDZ_2)

(296-392)

Peptidase family M50 (Peptidase_M50)

(294-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3D4RHV6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mitis NCTC 12261

53.634

98.519

0.528
  htrA Streptococcus pneumoniae Rx1

53.383

98.519

0.526
  htrA Streptococcus pneumoniae D39

53.383

98.519

0.526
  htrA Streptococcus pneumoniae R6

53.383

98.519

0.526
  htrA Streptococcus pneumoniae TIGR4

53.383

98.519

0.526
  htrA Streptococcus mutans UA159

56.085

93.333

0.523
  htrA Streptococcus gordonii str. Challis substr. CH1

54.22

96.543

0.523