Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   VNN41_RS05795 Genome accession   NZ_CP141713
Coordinates   1157892..1159109 (+) Length   405 a.a.
NCBI ID   WP_407349977.1    Uniprot ID   -
Organism   Lactococcus garvieae strain VC11     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1152892..1164109
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VNN41_RS05765 (VNN41_05750) eeP 1152903..1154150 (-) 1248 WP_407349974.1 RIP metalloprotease RseP Regulator
  VNN41_RS05770 (VNN41_05755) - 1154326..1155120 (-) 795 WP_003133509.1 phosphatidate cytidylyltransferase -
  VNN41_RS05775 (VNN41_05760) - 1155117..1155854 (-) 738 WP_407349975.1 isoprenyl transferase -
  VNN41_RS05780 (VNN41_05765) yajC 1156055..1156390 (-) 336 WP_014025468.1 preprotein translocase subunit YajC -
  VNN41_RS05785 (VNN41_05770) - 1156465..1157112 (-) 648 WP_407349976.1 DNA alkylation repair protein -
  VNN41_RS05790 (VNN41_05775) rlmH 1157109..1157588 (-) 480 WP_003133515.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  VNN41_RS05795 (VNN41_05780) htrA 1157892..1159109 (+) 1218 WP_407349977.1 S1C family serine protease Regulator
  VNN41_RS05800 (VNN41_05785) - 1159207..1160205 (+) 999 WP_407349978.1 glycosyltransferase family 4 protein -
  VNN41_RS05805 (VNN41_05790) - 1160218..1161552 (+) 1335 WP_407349979.1 glycosyltransferase family 4 protein -
  VNN41_RS05810 (VNN41_05795) - 1161603..1161827 (+) 225 WP_003133519.1 DUF1797 family protein -
  VNN41_RS05815 (VNN41_05800) - 1161853..1162903 (-) 1051 Protein_1122 BMP family protein -
  VNN41_RS05820 (VNN41_05805) - 1163062..1163811 (-) 750 WP_019298937.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 41814.66 Da        Isoelectric Point: 4.8808

>NTDB_id=918704 VNN41_RS05795 WP_407349977.1 1157892..1159109(+) (htrA) [Lactococcus garvieae strain VC11]
MAKKNIASLLITGVAGGAIALGGSAIYQNMTNTPSSNNTSDNSVSTVNVQVNTDTTKAIKKISNTVVSVLNYQKSSSNND
FEKIFGGGDTSSNDSNTPQLAGEGSGVIYKKDGNTAYIVTNYHVIEGASSLEVLMAGGQKVTAEVVGSDAYSDLAVLKID
AKYVKETATFGNSDKLTVGEPAIAVGSPLGSEYANSATEGIVSSLNRNVTLQNSQGQTINVNAIQTDAAINPGNSGGALI
NIQGQVIGITSSKITSTPSGTSGSGVSVEGMGFAIPANDVVNIINKLEKDGKVIRPALGVQMVNLSSLSQNMLASLNLPE
NVTNGVAIAEVQSGMPAAKAGLKQGDVIVKINDDEITSSVNLQSTLYKSSIGDTIKVTYYRDGKQATANIKLDKTSSDIN
FDKQN

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=918704 VNN41_RS05795 WP_407349977.1 1157892..1159109(+) (htrA) [Lactococcus garvieae strain VC11]
ATGGCAAAGAAAAATATCGCCTCATTACTTATTACGGGCGTAGCCGGAGGTGCTATCGCTCTTGGAGGTAGTGCTATCTA
CCAAAACATGACCAATACACCATCATCTAATAACACTTCGGACAATTCTGTAAGTACGGTTAACGTCCAAGTCAATACAG
ATACCACCAAAGCAATCAAGAAAATTTCGAACACTGTTGTTTCCGTTCTTAATTACCAAAAATCGTCCTCAAACAACGAT
TTTGAGAAGATTTTCGGTGGAGGCGATACAAGCAGCAATGACAGTAACACGCCCCAGCTGGCTGGTGAAGGTTCTGGTGT
TATTTATAAAAAAGATGGCAATACAGCATACATCGTCACCAACTATCACGTGATTGAAGGTGCTTCTTCCTTAGAAGTTC
TCATGGCTGGCGGTCAAAAAGTTACTGCTGAAGTTGTTGGTTCTGATGCTTATTCTGATTTAGCTGTCCTCAAAATTGAT
GCTAAGTATGTCAAAGAAACAGCAACATTCGGTAACTCTGACAAACTTACTGTTGGTGAGCCCGCTATCGCGGTTGGTTC
TCCTCTTGGAAGTGAGTATGCCAACTCAGCAACGGAAGGGATTGTTTCAAGTCTTAATCGTAATGTTACGCTGCAAAACA
GCCAAGGCCAAACAATTAATGTGAACGCAATTCAAACCGATGCAGCAATTAACCCAGGTAACTCTGGTGGTGCACTCATA
AATATTCAGGGACAAGTCATCGGGATTACTTCAAGTAAAATTACCTCAACACCAAGCGGAACAAGCGGCAGTGGTGTTTC
TGTAGAAGGAATGGGCTTTGCGATACCAGCCAATGATGTGGTCAATATTATCAATAAGTTGGAAAAAGATGGCAAAGTTA
TTCGACCTGCTCTCGGTGTACAAATGGTCAACTTGTCAAGTCTTTCACAAAATATGTTGGCTTCACTTAATCTTCCTGAA
AATGTGACAAATGGTGTTGCTATCGCTGAAGTTCAATCAGGAATGCCTGCTGCCAAAGCTGGACTCAAGCAAGGTGACGT
TATTGTCAAAATCAATGATGACGAAATCACTTCAAGTGTGAACCTTCAAAGTACACTTTATAAGTCATCGATTGGTGATA
CGATTAAGGTAACTTATTATCGTGACGGAAAACAAGCTACTGCGAATATCAAGTTGGATAAGACAAGTAGTGACATCAAC
TTTGACAAACAAAATTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(296-392)

Trypsin-like peptidase domain (Trypsin_2)

(104-249)

Peptidase family M50 (Peptidase_M50)

(297-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus gordonii str. Challis substr. CH1

54.476

96.543

0.526
  htrA Streptococcus mitis NCTC 12261

53.383

98.519

0.526
  htrA Streptococcus pneumoniae R6

53.133

98.519

0.523
  htrA Streptococcus pneumoniae TIGR4

53.133

98.519

0.523
  htrA Streptococcus pneumoniae D39

53.133

98.519

0.523
  htrA Streptococcus pneumoniae Rx1

53.133

98.519

0.523
  htrA Streptococcus mutans UA159

56.15

92.346

0.519