Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   VNN32_RS06595 Genome accession   NZ_CP141703
Coordinates   1243753..1244448 (+) Length   231 a.a.
NCBI ID   WP_019292077.1    Uniprot ID   A0A139ME49
Organism   Lactococcus petauri strain R21-74 AL-1     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1238753..1249448
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VNN32_RS06570 (VNN32_06565) - 1238986..1239687 (+) 702 WP_019292081.1 DeoR/GlpR family DNA-binding transcription regulator -
  VNN32_RS06575 (VNN32_06570) pfkB 1239684..1240610 (+) 927 WP_019292080.1 1-phosphofructokinase -
  VNN32_RS06580 (VNN32_06575) - 1240625..1242529 (+) 1905 WP_338975519.1 fructose-specific PTS transporter subunit EIIC -
  VNN32_RS06585 (VNN32_06580) - 1242641..1242883 (+) 243 WP_003135050.1 type B 50S ribosomal protein L31 -
  VNN32_RS06590 (VNN32_06585) - 1243100..1243651 (+) 552 WP_019292078.1 YceD family protein -
  VNN32_RS06595 (VNN32_06590) covR 1243753..1244448 (+) 696 WP_019292077.1 response regulator transcription factor Regulator
  VNN32_RS06600 (VNN32_06595) covS 1244536..1246026 (+) 1491 WP_338975521.1 HAMP domain-containing histidine kinase Regulator
  VNN32_RS06605 (VNN32_06600) - 1246422..1247993 (+) 1572 WP_019292075.1 ABC transporter permease subunit -
  VNN32_RS06610 (VNN32_06605) - 1247994..1248731 (+) 738 WP_046400798.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 27037.77 Da        Isoelectric Point: 5.2713

>NTDB_id=918594 VNN32_RS06595 WP_019292077.1 1243753..1244448(+) (covR) [Lactococcus petauri strain R21-74 AL-1]
MNSSKRILIIEDDKNIARFVSLELEHEGYQTAVQDNGRKGLEEAMSKDYDLILLDLMLPELDGFEVARRLRREKDTHIIM
MTARDSTMDRVAGLDIGADDYITKPFAIEELLARVRSLFRREDHIHTIEKSDNTSFRDLVIDKTNRTVHRGKKVIDLTRR
EYDLLLTLMQNVGDVVTREYLVSEVWGYEEGTETNVVDVYIRYLRNKIDVEGRESYIQTVRGMGYVMRDRK

Nucleotide


Download         Length: 696 bp        

>NTDB_id=918594 VNN32_RS06595 WP_019292077.1 1243753..1244448(+) (covR) [Lactococcus petauri strain R21-74 AL-1]
ATGAATTCATCTAAACGTATTTTGATTATCGAAGACGATAAAAACATTGCGAGATTTGTTTCACTTGAGCTTGAACACGA
AGGATATCAAACTGCGGTTCAAGACAATGGTCGTAAAGGTCTTGAAGAAGCAATGTCAAAAGATTATGATTTGATTTTGC
TCGACTTAATGCTCCCAGAGCTGGATGGCTTTGAAGTTGCACGACGCTTACGCCGTGAAAAAGATACACATATTATTATG
ATGACTGCACGTGATTCAACTATGGACCGTGTAGCAGGTCTTGATATTGGAGCGGATGACTATATTACAAAACCATTCGC
AATTGAAGAATTGTTAGCGCGTGTCCGTTCACTCTTCCGTCGTGAAGACCATATCCACACGATTGAAAAATCAGACAATA
CTTCATTCCGTGATTTGGTAATTGATAAAACAAACCGCACTGTACATCGCGGAAAAAAAGTTATTGACCTTACACGTCGT
GAATACGATTTGCTTTTGACCCTGATGCAAAATGTGGGTGATGTCGTAACACGCGAATACTTGGTTTCTGAAGTATGGGG
TTACGAAGAAGGTACAGAAACAAACGTTGTTGACGTTTATATCCGCTATTTGCGTAACAAAATTGACGTGGAAGGCCGCG
AAAGTTATATTCAAACGGTTCGTGGTATGGGATATGTCATGCGTGACCGCAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-227)

Response regulator receiver domain (Response_reg)

(7-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A139ME49

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Lactococcus lactis subsp. lactis strain DGCC12653

88.21

99.134

0.874
  covR Streptococcus salivarius strain HSISS4

67.241

100

0.675
  vicR Streptococcus mutans UA159

43.723

100

0.437
  micA Streptococcus pneumoniae Cp1015

42.424

100

0.424