Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   VNN32_RS06600 Genome accession   NZ_CP141703
Coordinates   1244536..1246026 (+) Length   496 a.a.
NCBI ID   WP_338975521.1    Uniprot ID   -
Organism   Lactococcus petauri strain R21-74 AL-1     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1239536..1251026
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VNN32_RS06575 (VNN32_06570) pfkB 1239684..1240610 (+) 927 WP_019292080.1 1-phosphofructokinase -
  VNN32_RS06580 (VNN32_06575) - 1240625..1242529 (+) 1905 WP_338975519.1 fructose-specific PTS transporter subunit EIIC -
  VNN32_RS06585 (VNN32_06580) - 1242641..1242883 (+) 243 WP_003135050.1 type B 50S ribosomal protein L31 -
  VNN32_RS06590 (VNN32_06585) - 1243100..1243651 (+) 552 WP_019292078.1 YceD family protein -
  VNN32_RS06595 (VNN32_06590) covR 1243753..1244448 (+) 696 WP_019292077.1 response regulator transcription factor Regulator
  VNN32_RS06600 (VNN32_06595) covS 1244536..1246026 (+) 1491 WP_338975521.1 HAMP domain-containing histidine kinase Regulator
  VNN32_RS06605 (VNN32_06600) - 1246422..1247993 (+) 1572 WP_019292075.1 ABC transporter permease subunit -
  VNN32_RS06610 (VNN32_06605) - 1247994..1248731 (+) 738 WP_046400798.1 amino acid ABC transporter ATP-binding protein -
  VNN32_RS06615 (VNN32_06610) murD 1248871..1250232 (+) 1362 WP_019292073.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -

Sequence

Protein


Download         Length: 496 a.a.        Molecular weight: 56839.95 Da        Isoelectric Point: 5.4142

>NTDB_id=918595 VNN32_RS06600 WP_338975521.1 1244536..1246026(+) (covS) [Lactococcus petauri strain R21-74 AL-1]
MVKFFDSKKKKAENLPERKRSIMLRWAFANTIFCFITFTIFTVLVYQLTITTFINSEKEDMMKALDNVEQSLSQSESKLS
EDNLANYLAYAKDYTASSQGKENELEILGSMIGSRKSFYVFDVGENLIYSTNSYGFPLRKDVGDSTHAVRTFGEYSGYLV
ERPVHSKKTGKLIGYVQAFYDMSYYYSVRTKLLIALIILEIIALFIAQFVGYFMASRYIKPLERLHDAITTRANNLKADF
KPVVIQTGDEIEELATVYNDMMIKLNDYVDQQKRFVSDVSHELRTPLAVLDGHLNLLNRWGKNDPEVLEESLQASIEEVS
TMRTMLEEMLALARLESIDSQDEDLICDPTEVSNFLKKNFLLIHPDLNLTVENYLTPGSLAHIYPNHYEQGLKILIDNAI
KYSPKDRQEVKIHLEEDNKYIITTVEDRGYGISQEDLKHVFERFFRADKARNRDIGGTGLGLSIIQRIVENYDGDVSVTS
IVGEGSKFTLKIPKIK

Nucleotide


Download         Length: 1491 bp        

>NTDB_id=918595 VNN32_RS06600 WP_338975521.1 1244536..1246026(+) (covS) [Lactococcus petauri strain R21-74 AL-1]
ATGGTAAAATTTTTTGATTCGAAGAAGAAAAAAGCAGAAAATCTGCCCGAGCGTAAGCGAAGCATCATGCTACGTTGGGC
CTTTGCAAATACGATTTTTTGTTTTATAACCTTCACTATTTTTACAGTATTAGTTTATCAACTGACCATAACAACCTTCA
TCAATTCTGAAAAAGAGGACATGATGAAAGCTCTGGACAATGTTGAGCAAAGTTTGTCCCAATCGGAAAGCAAACTGTCG
GAGGACAATCTTGCAAATTATTTGGCTTATGCCAAAGACTACACAGCATCCAGTCAGGGAAAAGAAAATGAGCTAGAAAT
ACTTGGAAGTATGATTGGTTCTAGGAAGTCTTTTTATGTCTTTGATGTCGGTGAAAATTTGATTTATTCGACCAATTCGT
ATGGTTTCCCGCTAAGGAAAGATGTGGGGGATTCTACTCATGCTGTACGTACATTTGGTGAATATTCTGGTTATTTGGTT
GAACGACCCGTTCATTCTAAGAAAACAGGGAAACTGATTGGCTATGTGCAGGCTTTCTATGATATGAGTTATTATTACAG
CGTGCGAACAAAGCTGCTGATTGCCTTGATTATCTTAGAAATTATTGCTCTCTTTATTGCTCAGTTTGTCGGTTATTTTA
TGGCAAGTCGCTATATCAAGCCTCTAGAGCGTTTGCACGATGCGATTACTACACGTGCCAATAATTTGAAGGCGGATTTC
AAACCTGTAGTGATTCAAACAGGCGATGAAATTGAAGAACTGGCGACTGTTTATAACGATATGATGATTAAGCTTAACGA
TTACGTTGATCAGCAGAAACGTTTTGTTTCTGATGTCAGTCACGAGCTACGTACGCCACTTGCAGTTTTAGATGGTCATT
TGAATCTCTTGAATCGATGGGGGAAAAATGATCCTGAAGTGCTTGAGGAGTCTTTACAGGCCAGTATAGAAGAAGTTAGC
ACGATGAGAACGATGTTAGAGGAGATGCTTGCATTGGCCCGTCTTGAAAGCATTGATTCTCAAGATGAAGATCTGATCTG
TGATCCAACAGAAGTTTCTAATTTTCTTAAGAAAAACTTTCTCCTTATTCATCCTGATTTAAATTTAACTGTTGAGAATT
ACTTGACGCCGGGTAGTTTGGCTCATATTTATCCCAACCATTATGAACAAGGCTTAAAAATTTTGATTGATAATGCGATA
AAATACTCGCCTAAAGATCGCCAAGAAGTGAAAATCCATCTAGAAGAAGATAACAAATACATTATTACGACAGTTGAGGA
TCGTGGCTATGGCATTAGTCAAGAAGATTTAAAACATGTCTTTGAGCGCTTTTTCCGTGCCGATAAAGCACGAAATCGAG
ATATAGGTGGAACAGGTCTTGGTCTGTCTATTATCCAACGCATAGTGGAAAACTATGACGGGGATGTCAGTGTGACTTCC
ATTGTAGGCGAAGGATCGAAATTTACTTTAAAAATTCCTAAGATTAAATAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(389-494)

HAMP domain (HAMP)

(214-266)

His Kinase A (phospho-acceptor) domain (HisKA)

(272-337)

ArlS sensor domain (ArlS_N)

(52-190)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Lactococcus lactis subsp. lactis strain DGCC12653

55.823

100

0.56