Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   VNN27_RS04245 Genome accession   NZ_CP141700
Coordinates   861295..862512 (-) Length   405 a.a.
NCBI ID   WP_019291567.1    Uniprot ID   A0AAJ2IZW6
Organism   Lactococcus petauri strain R22-25 IC35     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 856295..867512
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VNN27_RS04220 (VNN27_04220) - 856593..857342 (+) 750 WP_346350181.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  VNN27_RS04225 (VNN27_04225) - 857501..858550 (+) 1050 WP_346350182.1 BMP family protein -
  VNN27_RS04230 (VNN27_04230) - 858578..858802 (-) 225 WP_003133519.1 DUF1797 family protein -
  VNN27_RS04235 (VNN27_04235) - 858853..860187 (-) 1335 WP_019291569.1 glycosyltransferase family 4 protein -
  VNN27_RS04240 (VNN27_04240) - 860200..861198 (-) 999 WP_019291568.1 glycosyltransferase family 4 protein -
  VNN27_RS04245 (VNN27_04245) htrA 861295..862512 (-) 1218 WP_019291567.1 trypsin-like peptidase domain-containing protein Regulator
  VNN27_RS04250 (VNN27_04250) rlmH 862816..863295 (+) 480 WP_019291566.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  VNN27_RS04255 (VNN27_04255) - 863292..863939 (+) 648 WP_285124202.1 DNA alkylation repair protein -
  VNN27_RS04260 (VNN27_04260) yajC 864014..864349 (+) 336 WP_019292982.1 preprotein translocase subunit YajC -
  VNN27_RS04265 (VNN27_04265) - 864549..865286 (+) 738 WP_019292981.1 isoprenyl transferase -
  VNN27_RS04270 (VNN27_04270) - 865283..866077 (+) 795 WP_019291563.1 phosphatidate cytidylyltransferase -
  VNN27_RS04275 (VNN27_04275) eeP 866254..867501 (+) 1248 WP_086583290.1 RIP metalloprotease RseP Regulator

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 41831.68 Da        Isoelectric Point: 4.8866

>NTDB_id=918500 VNN27_RS04245 WP_019291567.1 861295..862512(-) (htrA) [Lactococcus petauri strain R22-25 IC35]
MAKKNIASLLITGVAGGAIALGGSAIYQNMTNTPSSNNTSDNSVSTVNVQVNTDTTKAIKKISNTVVSVLNYQKSSSSND
FEKIFGGGDTSSNESNTPQLAGEGSGVIYKKDGNTAYIVTNYHVIEGASSLEVLMAGGQKVTAEVVGSDAYSDLAVLKID
AKYVKETATFGNSDKLTVGEPAIAVGSPLGSEYANSATEGIVSSLNRNVTLQNSQGQTINVNAIQTDAAINPGNSGGALI
NIQGQVIGITSSKITSTPSGTSSSGVSVEGMGFAIPANDVVNIINKLEKDGKVIRPALGVQMVNLSSLSQNMLASLNLPE
NVTNGVAIAEVQSGMPAAKAGLKQGDVIVKINDDEITSSVNLQSTLYKSSIGDTIKVTYYRDGKQATANIKLDKTSSDIN
FDKQN

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=918500 VNN27_RS04245 WP_019291567.1 861295..862512(-) (htrA) [Lactococcus petauri strain R22-25 IC35]
ATGGCAAAAAAAAATATCGCCTCATTACTTATTACAGGCGTAGCCGGAGGTGCTATCGCTCTCGGAGGTAGTGCTATCTA
CCAAAATATGACCAACACGCCGTCATCTAACAACACTTCGGACAATTCTGTAAGTACAGTTAACGTCCAAGTAAATACAG
ATACTACAAAAGCAATCAAGAAAATTTCGAACACTGTTGTTTCCGTTCTTAATTACCAAAAATCGTCCTCAAGCAACGAT
TTTGAGAAGATTTTCGGCGGAGGCGATACAAGTAGCAATGAGAGTAATACGCCACAGCTGGCTGGAGAGGGTTCTGGTGT
TATTTACAAAAAGGATGGCAATACAGCATATATCGTCACCAACTATCACGTTATTGAAGGTGCTTCTTCCTTAGAAGTTC
TCATGGCCGGCGGTCAAAAAGTTACTGCTGAAGTTGTTGGTTCTGATGCTTATTCTGATTTAGCTGTCCTCAAAATTGAT
GCTAAGTATGTCAAAGAAACAGCAACATTCGGCAACTCTGACAAACTTACTGTTGGTGAGCCCGCTATCGCGGTGGGTTC
TCCCCTTGGAAGTGAGTATGCAAACTCAGCAACAGAAGGAATTGTTTCAAGTCTAAATCGCAATGTTACACTGCAAAACA
GCCAAGGCCAAACAATTAATGTTAACGCTATTCAAACCGATGCAGCTATTAACCCCGGTAACTCTGGTGGTGCACTCATA
AATATTCAAGGACAAGTCATCGGGATTACCTCAAGTAAAATTACCTCAACACCAAGCGGAACAAGCAGTAGTGGTGTCTC
TGTAGAAGGTATGGGATTTGCGATTCCAGCCAATGATGTCGTTAACATTATCAATAAGTTGGAAAAAGATGGCAAAGTTA
TTCGACCTGCTCTCGGTGTACAAATGGTCAACTTGTCAAGTCTTTCCCAAAACATGTTAGCTTCACTTAACCTTCCTGAA
AACGTGACTAACGGTGTTGCTATCGCTGAAGTTCAATCAGGAATGCCTGCTGCCAAAGCTGGACTCAAGCAAGGCGACGT
TATTGTCAAAATCAATGATGACGAAATCACTTCAAGCGTGAACCTTCAAAGTACACTTTATAAGTCTTCAATTGGTGATA
CGATTAAGGTAACTTATTATCGTGACGGAAAACAGGCTACTGCGAATATCAAATTGGATAAAACAAGTAGTGATATCAAC
TTTGACAAACAAAATTAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(104-249)

Peptidase family M50 (Peptidase_M50)

(288-396)

PDZ domain (PDZ_2)

(296-392)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus gordonii str. Challis substr. CH1

54.476

96.543

0.526
  htrA Streptococcus mutans UA159

56.349

93.333

0.526
  htrA Streptococcus mitis NCTC 12261

52.882

98.519

0.521
  htrA Streptococcus pneumoniae TIGR4

52.632

98.519

0.519
  htrA Streptococcus pneumoniae D39

52.632

98.519

0.519
  htrA Streptococcus pneumoniae Rx1

52.632

98.519

0.519
  htrA Streptococcus pneumoniae R6

52.632

98.519

0.519