Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   VNN43_RS01725 Genome accession   NZ_CP141685
Coordinates   338614..339309 (-) Length   231 a.a.
NCBI ID   WP_019292077.1    Uniprot ID   A0A139ME49
Organism   Lactococcus petauri strain R21-69 HC     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 333614..344309
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VNN43_RS01710 (VNN43_01710) - 334331..335068 (-) 738 WP_019292074.1 amino acid ABC transporter ATP-binding protein -
  VNN43_RS01715 (VNN43_01715) - 335069..336640 (-) 1572 WP_019293245.1 ABC transporter permease subunit -
  VNN43_RS01720 (VNN43_01720) covS 337036..338526 (-) 1491 WP_019293246.1 HAMP domain-containing histidine kinase Regulator
  VNN43_RS01725 (VNN43_01725) covR 338614..339309 (-) 696 WP_019292077.1 response regulator transcription factor Regulator
  VNN43_RS01730 (VNN43_01730) - 339411..339962 (-) 552 WP_206888295.1 YceD family protein -
  VNN43_RS01735 (VNN43_01735) - 340179..340421 (-) 243 WP_003135050.1 type B 50S ribosomal protein L31 -
  VNN43_RS01740 (VNN43_01740) - 340533..342437 (-) 1905 WP_019293248.1 fructose-specific PTS transporter subunit EIIC -
  VNN43_RS01745 (VNN43_01745) pfkB 342452..343378 (-) 927 WP_165719430.1 1-phosphofructokinase -
  VNN43_RS01750 (VNN43_01750) - 343375..344076 (-) 702 WP_019292081.1 DeoR/GlpR family DNA-binding transcription regulator -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 27037.77 Da        Isoelectric Point: 5.2713

>NTDB_id=917981 VNN43_RS01725 WP_019292077.1 338614..339309(-) (covR) [Lactococcus petauri strain R21-69 HC]
MNSSKRILIIEDDKNIARFVSLELEHEGYQTAVQDNGRKGLEEAMSKDYDLILLDLMLPELDGFEVARRLRREKDTHIIM
MTARDSTMDRVAGLDIGADDYITKPFAIEELLARVRSLFRREDHIHTIEKSDNTSFRDLVIDKTNRTVHRGKKVIDLTRR
EYDLLLTLMQNVGDVVTREYLVSEVWGYEEGTETNVVDVYIRYLRNKIDVEGRESYIQTVRGMGYVMRDRK

Nucleotide


Download         Length: 696 bp        

>NTDB_id=917981 VNN43_RS01725 WP_019292077.1 338614..339309(-) (covR) [Lactococcus petauri strain R21-69 HC]
ATGAATTCATCTAAACGTATTTTGATTATCGAAGACGATAAAAACATTGCGAGATTTGTTTCACTTGAGCTTGAACACGA
AGGATATCAAACTGCGGTTCAAGACAATGGTCGTAAAGGTCTTGAAGAAGCAATGTCAAAAGATTATGATTTGATTTTGC
TCGACTTAATGCTCCCAGAGCTGGATGGCTTTGAAGTTGCACGACGCTTACGTCGTGAAAAAGATACACATATTATTATG
ATGACTGCACGTGATTCAACAATGGACCGTGTAGCAGGTCTTGATATTGGAGCGGATGACTATATTACAAAACCATTCGC
AATTGAAGAATTGTTAGCGCGTGTCCGTTCACTCTTCCGTCGTGAAGACCATATCCATACGATTGAAAAATCAGACAATA
CTTCATTCCGTGATTTGGTAATTGATAAAACAAACCGCACTGTACATCGCGGAAAAAAAGTTATTGACCTTACACGTCGT
GAATACGATTTGCTTTTGACCCTGATGCAAAATGTGGGTGATGTCGTAACACGCGAATACTTGGTTTCTGAAGTATGGGG
TTACGAAGAAGGTACAGAAACAAACGTTGTTGACGTTTATATCCGCTATTTGCGTAACAAAATTGACGTGGAAGGCCGCG
AAAGTTATATTCAAACGGTTCGTGGTATGGGATATGTCATGCGTGACCGCAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-227)

Response regulator receiver domain (Response_reg)

(7-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A139ME49

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Lactococcus lactis subsp. lactis strain DGCC12653

88.21

99.134

0.874
  covR Streptococcus salivarius strain HSISS4

67.241

100

0.675
  vicR Streptococcus mutans UA159

43.723

100

0.437
  micA Streptococcus pneumoniae Cp1015

42.424

100

0.424