Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   AB0R82_RS20640 Genome accession   NZ_CP160220
Coordinates   4012193..4013395 (-) Length   400 a.a.
NCBI ID   WP_198878350.1    Uniprot ID   -
Organism   Bacillus subtilis strain JM553     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4007193..4018395
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB0R82_RS20615 (AB0R82_20615) rocE 4007424..4008827 (-) 1404 WP_003242721.1 amino acid permease -
  AB0R82_RS20620 (AB0R82_20620) rocD 4009050..4010255 (-) 1206 WP_033882758.1 ornithine aminotransferase -
  AB0R82_RS20625 (AB0R82_20625) rocR 4010496..4011881 (+) 1386 WP_198878351.1 arginine utilization regulatory protein RocR -
  AB0R82_RS20630 (AB0R82_20630) - 4011863..4012015 (-) 153 Protein_4008 ATP-binding protein -
  AB0R82_RS20635 (AB0R82_20635) - 4012043..4012172 (-) 130 Protein_4009 hypothetical protein -
  AB0R82_RS20640 (AB0R82_20640) htrA 4012193..4013395 (-) 1203 WP_198878350.1 serine protease HtrC Regulator
  AB0R82_RS20645 (AB0R82_20645) vicX 4013477..4014271 (-) 795 WP_003226939.1 MBL fold metallo-hydrolase Regulator
  AB0R82_RS20650 (AB0R82_20650) walI 4014293..4015135 (-) 843 WP_046161072.1 WalRK two-component regulatory system regulator WalI -
  AB0R82_RS20655 (AB0R82_20655) walH 4015122..4016489 (-) 1368 WP_046664054.1 WalRK two-component regulatory system regulator WalH -
  AB0R82_RS20660 (AB0R82_20660) walK 4016479..4018314 (-) 1836 WP_069703964.1 cell wall metabolism sensor histidine kinase WalK -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 42715.50 Da        Isoelectric Point: 5.3354

>NTDB_id=917671 AB0R82_RS20640 WP_198878350.1 4012193..4013395(-) (htrA) [Bacillus subtilis strain JM553]
MVDYEREEEHTTPEQPKRSKKGYFLSSLIGVIVGAVLMAFIMPYLSNEGLDTGALDQQQNNNGRESIRTVNVSVNNTVTK
IVSNVSPAVVGVVNIQKSDIRGESGEAGSGSGVIYKKNDHSAYVVTNHHVIEGASQIEISLKDGSRVSADLVGSDQLMDL
AVLRVKSDKIKAVADFGNSDKVKSGEPVIAIGNPLGLEFAGSVTQGVISGTERAIPVDSNGDGQPDWNAEVLQTDAAINP
GNSGGALLNMDGKVIGINSMKIAESAVEGIGLSIPSKLVIPVIEDLEKYGKVKRPFLGIEMKSLSDIASYHWDETLKLPK
NVTNGAVVMGVDAFSPAGKAGLKELDVITEFDGFKVNDIVDLRKRLYQKKVGDRVKVKFYRGGKEKSVDIMLSSADQLGS

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=917671 AB0R82_RS20640 WP_198878350.1 4012193..4013395(-) (htrA) [Bacillus subtilis strain JM553]
ATGGTGGATTACGAACGTGAGGAAGAACATACTACTCCTGAACAGCCAAAGAGAAGTAAAAAAGGATATTTTCTTTCTAG
CCTGATTGGTGTGATTGTCGGTGCCGTATTAATGGCGTTTATCATGCCGTATCTTTCAAATGAAGGGCTAGATACGGGCG
CTTTAGATCAGCAGCAGAACAATAACGGCCGGGAATCAATCAGGACGGTGAATGTCAGTGTCAACAATACGGTCACCAAG
ATTGTCAGCAATGTGTCGCCCGCCGTTGTGGGTGTTGTGAACATCCAAAAATCAGATATACGGGGAGAGAGCGGCGAGGC
TGGGAGCGGCTCTGGCGTCATCTATAAGAAAAATGACCATTCCGCTTATGTCGTGACCAACCATCATGTCATCGAAGGCG
CTTCCCAAATTGAAATCAGCTTGAAAGACGGCTCACGTGTATCAGCTGATCTTGTCGGCAGCGACCAGCTGATGGACCTT
GCCGTTTTACGGGTGAAAAGCGATAAGATTAAAGCAGTCGCCGATTTCGGAAATTCAGATAAAGTGAAGTCTGGGGAGCC
GGTTATCGCGATCGGGAACCCGTTAGGCCTTGAGTTTGCTGGCTCTGTCACACAAGGCGTCATCTCGGGTACGGAGAGGG
CGATCCCAGTCGATTCAAACGGTGACGGACAGCCTGACTGGAACGCAGAAGTCCTGCAAACAGATGCGGCCATTAACCCT
GGGAACAGCGGCGGTGCTTTGTTAAATATGGATGGGAAGGTCATTGGCATCAATTCAATGAAAATTGCCGAGTCGGCGGT
TGAAGGGATTGGCCTGTCGATTCCATCTAAGCTCGTGATCCCTGTGATAGAGGATTTAGAGAAATACGGAAAGGTCAAAC
GCCCGTTCCTTGGCATTGAGATGAAATCCCTAAGCGACATCGCAAGCTATCATTGGGATGAAACATTAAAGCTTCCTAAG
AACGTCACCAATGGAGCGGTTGTGATGGGTGTAGACGCCTTTTCACCTGCCGGAAAAGCGGGACTGAAGGAACTCGATGT
CATCACGGAATTTGACGGATTCAAAGTAAATGATATTGTTGACCTGCGAAAACGGCTTTATCAGAAAAAAGTCGGTGACC
GGGTGAAGGTGAAGTTTTACCGCGGCGGAAAAGAAAAATCTGTTGACATCATGCTGTCGTCCGCAGACCAATTAGGAAGT
TAA

Domains

Predicted by InterProScan.

Peptidase family M50 (Peptidase_M50)

(197-395)

PDZ domain (PDZ_2)

(295-392)

Trypsin-like peptidase domain (Trypsin_2)

(110-257)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

43.829

99.25

0.435
  htrA Streptococcus gordonii str. Challis substr. CH1

41.791

100

0.42
  htrA Streptococcus mitis NCTC 12261

43.005

96.5

0.415
  htrA Streptococcus pneumoniae TIGR4

45.758

82.5

0.378
  htrA Streptococcus pneumoniae D39

45.758

82.5

0.378
  htrA Streptococcus pneumoniae Rx1

45.758

82.5

0.378
  htrA Streptococcus pneumoniae R6

45.758

82.5

0.378