Detailed information NTG0917027

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: T1M39_RS08645
• Genome accession: NZ_CP141327
• Coordinates: 1800261..1802453 (-)
• Length: 730 a.a.
• NCBI ID: WP_003567347.1
• Uniprot ID: A0A826HY20
• Organism: Lacticaseibacillus paracasei strain S135-24W
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1795261..1807453

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
T1M39_RS08615 (T1M39_08615)	-	1795427..1795711 (-)	285	WP_003567331.1	bacteriocin immunity protein	-
T1M39_RS08620 (T1M39_08620)	-	1795904..1796200 (-)	297	WP_003567333.1	bacteriocin immunity protein	-
T1M39_RS08625 (T1M39_08625)	-	1796302..1797657 (-)	1356	WP_096772795.1	threonine/serine exporter ThrE family protein	-
T1M39_RS08630 (T1M39_08630)	-	1797963..1798274 (-)	312	WP_003580849.1	hypothetical protein	-
T1M39_RS08635 (T1M39_08635)	-	1798347..1798697 (-)	351	WP_003567340.1	hypothetical protein	-
T1M39_RS08640 (T1M39_08640)	-	1798871..1800250 (-)	1380	WP_003567343.1	bacteriocin secretion accessory protein	-
T1M39_RS08645 (T1M39_08645)	comA	1800261..1802453 (-)	2193	WP_003567347.1	peptide cleavage/export ABC transporter	Regulator
T1M39_RS08650 (T1M39_08650)	-	1802919..1803056 (-)	138	WP_003571414.1	bacteriocin-like peptide, LSEI_2386 family	-
T1M39_RS08655 (T1M39_08655)	-	1803246..1803722 (+)	477	Protein_1673	histidine kinase	-
T1M39_RS08660 (T1M39_08660)	-	1803857..1805275 (+)	1419	WP_003590800.1	IS5 family transposase	-
T1M39_RS08665 (T1M39_08665)	-	1805288..1806115 (+)	828	Protein_1675	GHKL domain-containing protein	-
T1M39_RS08670 (T1M39_08670)	-	1806120..1806926 (+)	807	WP_003567351.1	LytR/AlgR family response regulator transcription factor	-

Sequence

Protein

• Length: 730 a.a.
• Molecular weight: 81262.49 Da
• Isoelectric Point: 7.2447

>NTDB_id=917027 T1M39_RS08645 WP_003567347.1 1800261..1802453(-) (comA) [Lacticaseibacillus paracasei strain S135-24W]
MIKYNLKLGQAQYYKRYYTPQVDERDCGVAALNMLLQFNGSDYSLAHLRQLAKTDQEGTTALGIVRAAQALHFETKAVKA
DMTLFDLDDVPYPFLVHVLKRGELLHYYVVFKATKDHILIGDPDSSVAMTWLPKERFAKEWSGVAIFIAPEPQYQPRKED
KGSLFAFVPMLARQKGIIANIIVAAVLITLISIVGSYFLQSIIDTYIPNGMRTTLGMIASGLILAYVLQSVLTYGQNFLM
AVLGQRLSIDVILGYVRHLYELPMSFFSTRRTGEIVSRFSDANKIIDALANTIMTLFLDIWIVLILGIVLGIQNTTLFLV
SLIAVPCYLVIVFAFQRPFNRLNQETMESNAILSSSIIEDLNGIETIKSLTGEKVSYERVDREFVTYLKKSFNYTKADQL
QQAIKGLLKLVLNVVVLWIGASLVMANKMSLGQMLTFNALLAYFTNPLESIINLQPKLQMAKVANNRLNEVYLVESEFKE
QRSLNDRHLIDGAINVTDVSFKYGFGQDVLKQINLEIPANAKYTIVGMSGSGKSTLAKLLVGFYPVDTGKGKITFNGVPI
SDVDLTTLRQYIEYVPQDPFIFSGSVIENLTLGSRSNITEADIEAACSVAEIAGDISNLPQIWQTKLSESGSILSGGQKQ
RLAIARALLSPAKVLIFDESTSSLDTITERKIVDRLLAMTDRTIIFVAHRLTIAAKTEQIVVMDHGAIVEQGNHTELLAK
QGYYARLVSE

Nucleotide

• Length: 2193 bp

>NTDB_id=917027 T1M39_RS08645 WP_003567347.1 1800261..1802453(-) (comA) [Lacticaseibacillus paracasei strain S135-24W]
ATGATCAAATACAACCTAAAGCTCGGCCAAGCACAGTATTACAAGCGTTACTACACGCCTCAGGTGGATGAGCGCGATTG
CGGGGTTGCGGCGCTTAATATGCTGCTGCAATTTAATGGCTCGGATTATTCGCTAGCGCATCTGCGACAGTTGGCGAAGA
CGGATCAGGAAGGAACAACAGCGTTAGGGATTGTCCGAGCTGCTCAGGCGCTTCATTTTGAAACCAAGGCTGTCAAGGCG
GATATGACGCTGTTTGATCTTGATGATGTTCCTTATCCGTTTCTTGTCCATGTTTTGAAGCGTGGCGAGTTGCTTCATTA
TTATGTGGTGTTTAAGGCGACAAAGGATCATATCTTGATTGGCGATCCTGATTCATCAGTAGCGATGACCTGGCTTCCCA
AAGAGCGCTTTGCGAAGGAGTGGTCGGGGGTCGCTATTTTTATTGCGCCAGAACCGCAATATCAACCACGCAAAGAGGAC
AAAGGCAGTCTCTTTGCGTTTGTGCCGATGCTAGCGCGACAAAAAGGAATCATTGCCAATATTATTGTCGCCGCTGTGTT
GATCACGTTGATTAGTATTGTCGGGTCTTATTTTCTTCAGTCGATTATTGATACTTATATTCCAAACGGGATGCGCACAA
CTTTGGGAATGATTGCCAGTGGTCTCATCCTCGCTTATGTGCTGCAGTCGGTTTTAACCTATGGGCAAAATTTTTTGATG
GCTGTTTTAGGACAACGTTTGTCGATTGATGTCATTTTGGGTTACGTCAGACACCTTTATGAATTACCGATGTCCTTCTT
TTCCACGCGTCGGACTGGGGAAATTGTGTCGCGGTTTTCCGATGCTAATAAGATTATTGATGCGCTGGCAAACACGATTA
TGACCTTGTTTCTTGATATTTGGATTGTCTTAATTTTAGGGATCGTGTTAGGCATTCAAAACACCACCTTATTCTTGGTG
TCTTTAATTGCTGTGCCTTGTTATTTGGTGATTGTGTTCGCTTTTCAGCGGCCATTTAATCGACTGAATCAAGAGACGAT
GGAAAGCAATGCCATTTTGAGTTCATCTATTATCGAGGACTTGAACGGGATTGAGACGATTAAATCACTGACCGGTGAGA
AAGTCAGTTATGAACGGGTTGACCGTGAATTCGTCACGTATTTGAAAAAGTCGTTCAATTATACAAAAGCTGATCAACTG
CAGCAGGCGATCAAGGGACTGCTGAAGTTGGTTTTGAATGTGGTCGTGCTGTGGATTGGTGCGAGTTTGGTGATGGCTAA
CAAGATGAGTCTAGGACAGATGCTGACGTTCAATGCGTTGTTGGCATATTTCACTAATCCGTTAGAAAGCATCATTAATT
TGCAACCAAAATTGCAAATGGCCAAAGTCGCGAATAACCGGCTGAATGAAGTGTATTTGGTTGAATCGGAGTTTAAAGAA
CAGCGAAGTTTGAATGATCGGCATTTAATTGATGGCGCCATCAATGTTACCGATGTGTCCTTTAAGTATGGTTTTGGGCA
AGATGTTTTGAAACAAATCAACCTTGAAATCCCGGCGAATGCCAAATACACCATTGTCGGCATGAGTGGATCAGGGAAAT
CGACCTTAGCCAAGTTGCTAGTAGGTTTCTATCCAGTGGACACTGGCAAAGGGAAAATCACATTTAATGGTGTTCCCATC
AGTGATGTTGATCTAACAACGTTACGCCAATACATCGAGTATGTACCGCAAGATCCGTTTATTTTTTCTGGCTCAGTCAT
TGAAAACTTAACGTTGGGTAGCCGTTCGAATATCACTGAAGCCGATATTGAAGCTGCCTGTTCAGTGGCGGAAATTGCCG
GAGATATTTCGAATTTGCCGCAGATATGGCAGACCAAACTTTCTGAAAGCGGCAGTATTTTATCGGGTGGACAAAAGCAG
CGCCTAGCAATTGCCCGCGCGTTATTATCACCGGCAAAAGTGTTGATTTTTGATGAATCGACCAGCAGTTTAGATACGAT
CACCGAGCGAAAAATTGTTGATCGGTTGTTAGCGATGACTGATCGAACCATTATTTTTGTGGCTCATCGGCTCACTATTG
CTGCTAAAACGGAACAGATTGTGGTCATGGACCATGGTGCGATTGTTGAACAAGGAAATCATACTGAGTTATTGGCCAAA
CAAGGCTATTATGCTCGGTTGGTAAGTGAGTGA

Domains

Predicted by InterProScan.

• Peptidase C39 family (Peptidase_C39) (16-152)

• ABC transporter (ABC_tran) (510-662)

• ABC transporter transmembrane region (ABC_membrane) (180-448)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	58.635	98.356	0.577
comA	Streptococcus pneumoniae Rx1	58.078	98.356	0.571
comA	Streptococcus pneumoniae D39	58.078	98.356	0.571
comA	Streptococcus pneumoniae R6	58.078	98.356	0.571
comA	Streptococcus mitis SK321	57.939	98.356	0.57
comA	Streptococcus pneumoniae TIGR4	57.66	98.356	0.567
comA	Streptococcus gordonii str. Challis substr. CH1	57.103	98.356	0.562
comA/nlmT	Streptococcus mutans UA159	54.848	98.904	0.542