Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   U8P24_RS02395 Genome accession   NZ_CP141076
Coordinates   479182..480471 (-) Length   429 a.a.
NCBI ID   WP_002416060.1    Uniprot ID   A0AAV3GJE7
Organism   Enterococcus faecalis strain HRH55     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 474182..485471
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U8P24_RS02370 (U8P24_02370) - 474239..474694 (+) 456 WP_002383283.1 universal stress protein -
  U8P24_RS02375 (U8P24_02375) ytpR 474905..475525 (+) 621 WP_002361057.1 YtpR family tRNA-binding protein -
  U8P24_RS02380 (U8P24_02380) - 475847..476173 (+) 327 WP_010715459.1 hypothetical protein -
  U8P24_RS02385 (U8P24_02385) - 476261..478273 (+) 2013 WP_174092366.1 ABC transporter permease -
  U8P24_RS02390 (U8P24_02390) - 478270..478875 (+) 606 WP_002383287.1 ABC transporter ATP-binding protein -
  U8P24_RS02395 (U8P24_02395) htrA 479182..480471 (-) 1290 WP_002416060.1 S1C family serine protease Regulator
  U8P24_RS02400 (U8P24_02400) rlmH 480872..481351 (+) 480 WP_002383290.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  U8P24_RS02405 (U8P24_02405) - 481399..482241 (+) 843 WP_002381116.1 LEM-3-like GIY-YIG domain-containing protein -
  U8P24_RS02410 (U8P24_02410) - 482339..483742 (-) 1404 WP_002383291.1 dicarboxylate/amino acid:cation symporter -
  U8P24_RS02415 (U8P24_02415) gst 484075..484584 (+) 510 WP_002381118.1 DinB family glutathione transferase -
  U8P24_RS02420 (U8P24_02420) - 484723..485187 (+) 465 WP_002383292.1 RNA polymerase sigma factor -

Sequence

Protein


Download         Length: 429 a.a.        Molecular weight: 44502.68 Da        Isoelectric Point: 5.1271

>NTDB_id=915911 U8P24_RS02395 WP_002416060.1 479182..480471(-) (htrA) [Enterococcus faecalis strain HRH55]
MQRKDVTPNSDKKSLLQKFGIGLAGGLLGGALILGGAYSGIIPTPNGGNNAATTTSTNHGDTKVSNVSYNVSSDVTKAVK
KVQNSVVSVINMQSASNNSSADDPFGGLFGGNEGTQDSSGNNGNDLEAASEGSGVIYKKDGKTAYVVTNNHVVDKAQGLE
VVLSDGTKVKGELVGTDAYTDLAVIKISSDKVDQVAEFGNSSKITVGEPAIAIGSPLGSDYANSVTQGIISSVNRNITNK
NESGETININAIQTDAAINPGNSGGPLINIEGQVIGINSVKIVQSTSQVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPA
LGITMSDLTGISSQKQEQILKIPASVKTGVVVRGVEAATPAEKAGLEKYDVITKVDGQDVSSTTDLQSALYKKKVGDKME
VTYYRGSKEMKATIDLTIDKSALTQQNNR

Nucleotide


Download         Length: 1290 bp        

>NTDB_id=915911 U8P24_RS02395 WP_002416060.1 479182..480471(-) (htrA) [Enterococcus faecalis strain HRH55]
ATGCAACGAAAAGATGTTACACCTAATTCAGATAAAAAAAGTTTATTGCAAAAATTTGGGATTGGTTTAGCTGGCGGCTT
ACTTGGTGGCGCCCTTATTCTAGGAGGCGCTTATTCTGGGATTATTCCCACACCCAACGGCGGAAATAATGCGGCGACGA
CGACGTCCACTAATCACGGTGATACAAAAGTCAGCAATGTGAGTTACAATGTTTCTAGCGATGTCACAAAAGCCGTGAAA
AAAGTTCAAAATTCTGTGGTTTCTGTCATTAATATGCAAAGTGCTAGCAACAATTCTTCGGCTGATGATCCTTTTGGGGG
ATTGTTCGGTGGGAATGAAGGTACTCAAGACTCTTCCGGCAACAATGGTAACGATTTAGAAGCAGCCAGTGAAGGTAGTG
GGGTTATTTATAAGAAAGATGGTAAAACGGCTTATGTCGTGACAAATAACCACGTCGTAGATAAAGCACAAGGATTGGAA
GTTGTTTTGTCTGATGGTACCAAAGTGAAAGGCGAATTAGTCGGAACCGATGCTTATACGGATTTAGCCGTGATTAAAAT
TTCTTCCGACAAAGTTGATCAAGTCGCTGAGTTTGGGAATTCTAGTAAAATCACAGTCGGTGAGCCTGCTATTGCAATTG
GTTCCCCTCTAGGTTCTGATTATGCTAACTCTGTCACACAAGGAATCATCTCTTCTGTGAATAGAAATATTACCAATAAA
AACGAGTCTGGTGAAACCATCAATATTAATGCCATTCAAACCGATGCTGCCATCAATCCAGGAAACTCTGGTGGTCCACT
AATCAATATTGAAGGACAAGTCATTGGCATTAACTCAGTAAAAATTGTGCAATCAACTAGTCAAGTGAGCGTTGAAGGGA
TGGGCTTTGCCATTCCAAGTAATGACGTAGTCAACATTATCAACCAATTAGAAAAAGATGGTAAAGTGACACGGCCAGCT
CTTGGGATTACGATGTCTGATTTAACAGGTATCTCTTCACAAAAACAAGAACAAATTTTAAAAATTCCAGCTTCTGTAAA
AACTGGCGTAGTGGTTCGTGGTGTTGAAGCAGCGACCCCTGCTGAAAAAGCTGGATTGGAAAAATACGATGTTATCACGA
AAGTTGACGGCCAAGACGTAAGCTCTACTACAGATTTACAAAGCGCGCTTTACAAGAAAAAAGTTGGCGACAAAATGGAA
GTGACTTATTATCGTGGTTCTAAAGAAATGAAAGCAACCATCGATTTAACCATTGATAAATCAGCTTTAACACAACAAAA
TAATCGCTAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(132-277)

Peptidase family M50 (Peptidase_M50)

(9-416)

PDZ domain (PDZ_2)

(319-416)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus gordonii str. Challis substr. CH1

53.171

95.571

0.508
  htrA Streptococcus mutans UA159

58.63

85.082

0.499
  htrA Streptococcus mitis NCTC 12261

55.135

86.247

0.476
  htrA Streptococcus pneumoniae TIGR4

55.807

82.284

0.459
  htrA Streptococcus pneumoniae Rx1

55.807

82.284

0.459
  htrA Streptococcus pneumoniae D39

55.807

82.284

0.459
  htrA Streptococcus pneumoniae R6

55.807

82.284

0.459