Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   U0N78_RS08865 Genome accession   NZ_CP140109
Coordinates   1880964..1881686 (-) Length   240 a.a.
NCBI ID   WP_029175761.1    Uniprot ID   A0A123TMX7
Organism   Streptococcus suis strain 2022WUSS148     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1875964..1886686
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0N78_RS08845 (U0N78_08845) - 1876009..1877235 (-) 1227 WP_043025948.1 cysteine desulfurase -
  U0N78_RS08850 (U0N78_08850) sufD 1877237..1878499 (-) 1263 WP_043025950.1 Fe-S cluster assembly protein SufD -
  U0N78_RS08855 (U0N78_08855) sufC 1878516..1879289 (-) 774 WP_002938165.1 Fe-S cluster assembly ATPase SufC -
  U0N78_RS08860 (U0N78_08860) - 1879795..1880967 (-) 1173 WP_043026046.1 glycosyltransferase family 4 protein -
  U0N78_RS08865 (U0N78_08865) mecA 1880964..1881686 (-) 723 WP_029175761.1 adaptor protein MecA Regulator
  U0N78_RS08870 (U0N78_08870) - 1881814..1882650 (-) 837 WP_015647359.1 undecaprenyl-diphosphate phosphatase -
  U0N78_RS08875 (U0N78_08875) - 1882789..1884354 (+) 1566 WP_043026044.1 ABC transporter substrate-binding protein/permease -
  U0N78_RS08880 (U0N78_08880) - 1884347..1885090 (+) 744 WP_043026042.1 amino acid ABC transporter ATP-binding protein -
  U0N78_RS08885 (U0N78_08885) - 1885218..1885427 (-) 210 WP_029178990.1 hypothetical protein -
  U0N78_RS08890 (U0N78_08890) - 1885513..1886415 (-) 903 WP_002942264.1 SPFH domain-containing protein -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 28035.58 Da        Isoelectric Point: 4.0497

>NTDB_id=912593 U0N78_RS08865 WP_029175761.1 1880964..1881686(-) (mecA) [Streptococcus suis strain 2022WUSS148]
MKVKQISDSTLKITIKLDDLEERGMELSDFLIPQEKTEEFFYTVLDELDLPMTFRESGMLSFRVTPKPDRVDIFVTKSDL
DQSLNFDEFTDFSELGDVASMTPDEFFKSLEQTVREKSAPDATAVRHLEEVEQEEEVDEEEQERYIYYILEFPTIEDLFT
FVGTVDYPVEESELYKMDGHYYLTVLINVENRSKQYPGYILSRMLEFTNDTKLTRPALQEHGTLMLPLAAIEELRKVPTV

Nucleotide


Download         Length: 723 bp        

>NTDB_id=912593 U0N78_RS08865 WP_029175761.1 1880964..1881686(-) (mecA) [Streptococcus suis strain 2022WUSS148]
ATGAAAGTAAAGCAAATTAGTGATTCAACCTTGAAAATCACTATAAAATTAGATGATTTGGAAGAGAGAGGAATGGAACT
TTCGGACTTTCTCATTCCGCAAGAAAAGACAGAGGAGTTCTTCTATACTGTTTTGGATGAATTGGATTTACCAATGACTT
TCCGAGAAAGTGGTATGCTGAGTTTTCGTGTAACTCCGAAGCCAGATCGGGTAGACATCTTTGTTACCAAATCTGATTTG
GATCAGAGCTTGAATTTCGATGAATTTACAGATTTTTCGGAACTTGGTGATGTTGCAAGTATGACTCCAGATGAGTTTTT
CAAGAGTTTGGAGCAAACCGTTCGTGAGAAAAGTGCACCGGATGCAACAGCCGTTCGTCATTTGGAAGAGGTAGAGCAAG
AGGAAGAAGTAGATGAAGAGGAGCAGGAGCGCTATATTTACTATATTTTGGAATTTCCAACGATAGAGGATCTGTTTACT
TTTGTTGGTACGGTTGATTATCCAGTAGAAGAATCGGAATTATATAAAATGGATGGTCACTACTACTTGACCGTTCTTAT
CAATGTAGAAAATCGTTCCAAGCAGTATCCAGGCTACATTCTCTCACGAATGTTGGAATTTACCAATGATACTAAGTTGA
CCAGACCTGCTTTACAAGAACACGGAACTTTGATGCTTCCACTTGCGGCAATCGAGGAGCTTAGGAAGGTTCCGACAGTA
TGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A123TMX7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

51.23

100

0.521
  mecA Streptococcus pneumoniae D39

51.23

100

0.521
  mecA Streptococcus pneumoniae R6

51.23

100

0.521
  mecA Streptococcus pneumoniae TIGR4

51.23

100

0.521
  mecA Streptococcus mutans UA159

49.59

100

0.504
  mecA Streptococcus thermophilus LMD-9

47.917

100

0.479
  mecA Streptococcus thermophilus LMG 18311

47.5

100

0.475