Detailed information NTG0091247

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: L6411_RS06760
• Genome accession: NZ_AP025333
• Coordinates: 1397798..1400032 (-)
• Length: 744 a.a.
• NCBI ID: WP_237373949.1
• Uniprot ID: -
• Organism: Streptococcus ruminantium strain GUT-189
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1392798..1405032

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L6411_RS06735 (GUT189_12910)	-	1393500..1393664 (-)	165	WP_155972019.1	transposon-encoded TnpW family protein	-
L6411_RS06740 (GUT189_12920)	-	1393791..1394414 (-)	624	WP_120171912.1	helix-turn-helix domain-containing protein	-
L6411_RS09995	-	1394660..1394850 (-)	191	Protein_1288	recombinase	-
L6411_RS06745 (GUT189_12940)	sodA	1395043..1395654 (-)	612	WP_024532641.1	superoxide dismutase SodA	-
L6411_RS06750 (GUT189_12950)	holA	1395751..1396782 (-)	1032	WP_237373948.1	DNA polymerase III subunit delta	-
L6411_RS06755 (GUT189_12960)	-	1397038..1397652 (-)	615	WP_227990611.1	hypothetical protein	-
L6411_RS06760 (GUT189_12970)	comEC/celB	1397798..1400032 (-)	2235	WP_237373949.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
L6411_RS06765 (GUT189_12980)	comEA	1400016..1400672 (-)	657	WP_024532637.1	helix-hairpin-helix domain-containing protein	Machinery gene
L6411_RS06770 (GUT189_12990)	-	1400757..1401500 (-)	744	WP_024532636.1	lysophospholipid acyltransferase family protein	-
L6411_RS06775 (GUT189_13000)	-	1401691..1403136 (+)	1446	WP_156021108.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-
L6411_RS06780 (GUT189_13010)	-	1403496..1404284 (+)	789	WP_024532634.1	ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 744 a.a.
• Molecular weight: 84906.74 Da
• Isoelectric Point: 9.7066

>NTDB_id=91247 L6411_RS06760 WP_237373949.1 1397798..1400032(-) (comEC/celB) [Streptococcus ruminantium strain GUT-189]
MLRLDKLPCQPIHLAILAVVTYFTVHRFSMLTMSLLILLLVIYWRRQGKVTFFKMLPLLVLCGLFFGCQKLKWKQEEQAV
SKQVTAVEIVPDTININGDQLSFRARTDGQIYQGFYKLTSQKEQEYFQKLTALVQVEVKAETSLPSGQRNFNGFDYQAYL
KTQGIYRILTIATINKIVPIHSWNPMDWLSIWRRKALVFIKSNFPSPMSHYMTGLLFGELDSDFDQMSALYSSLGIIHLF
ALSGMQVGFFIDKFRWILLRLGLTKETVDQLQVPFSLVYAGLTGFSVSVVRSLIQKILSNLGLRKLDNFAATLFICFLVQ
PRFLLTVGGVLTFTYAFLLTVFDFEDLKQIKKVVVESLSISLGILPILMTYFYAFQPLSILLTFFFSFVFDVLLLPSLSV
IFLLSPLVKITWVNSFFVLMEKMIIWVSDLGFRPLILGKPSDFILLVLLLGFFMLYDFHRQKKWLLGLSLLLTLLFFITK
HPLENEVTVVDIGQGDSIFLRDMQGRTVLIDVGGRVDFTVKEGWKARSRQANAERTLIPYLHSRGVDKIDSLVLTHTDTD
HVGDVLEVAKNFKIGKIYVSSGSLTVPSFVTTLKKINVPVHVVQVGDRLPIVDSYLEVLYPSRSGDGSNNDSIVLYGRLL
GINFLFTGDLEEGELELIKTYPKLSVDVLKAGHHGSKGSSYPEFLDHIGAKIALISAGEKNRYKHPHQETLERFEQKNMQ
IYRTDRQGAIRFRGWRSWSIETVR

Nucleotide

• Length: 2235 bp

>NTDB_id=91247 L6411_RS06760 WP_237373949.1 1397798..1400032(-) (comEC/celB) [Streptococcus ruminantium strain GUT-189]
ATGTTACGGTTGGATAAGCTCCCCTGTCAGCCTATACATCTAGCCATTTTGGCGGTCGTGACCTACTTTACGGTTCACCG
TTTTTCGATGTTGACAATGAGCCTTCTGATATTATTATTGGTAATCTATTGGCGGCGTCAGGGGAAAGTTACTTTTTTTA
AAATGCTGCCGCTTCTAGTCTTATGCGGTCTATTCTTCGGCTGCCAAAAGCTCAAATGGAAACAGGAAGAGCAGGCTGTT
TCAAAGCAAGTGACTGCTGTAGAGATTGTGCCGGATACTATAAATATCAATGGCGATCAGTTATCTTTCCGTGCTAGGAC
TGATGGTCAGATTTATCAAGGTTTCTATAAGCTAACTAGTCAGAAAGAACAGGAGTATTTCCAAAAGCTAACAGCTCTTG
TTCAGGTGGAGGTGAAGGCAGAGACGAGTCTCCCATCAGGTCAGCGGAATTTCAATGGTTTTGATTATCAAGCCTATTTA
AAAACACAGGGAATCTATCGAATCCTCACCATAGCGACTATCAATAAGATCGTACCTATTCACTCTTGGAACCCTATGGA
TTGGTTGTCAATTTGGCGGAGAAAAGCCTTGGTTTTCATCAAATCTAATTTTCCTTCCCCCATGAGCCATTACATGACAG
GGTTGCTTTTTGGAGAGTTGGACAGTGACTTTGATCAGATGAGCGCCCTTTATTCCAGTCTGGGGATTATCCATCTCTTT
GCTCTATCAGGAATGCAGGTAGGTTTTTTCATTGATAAGTTTCGCTGGATTTTACTGCGTTTAGGCTTGACAAAGGAGAC
AGTTGATCAATTACAAGTCCCCTTTTCTTTGGTCTATGCTGGTTTGACAGGCTTTTCTGTATCAGTCGTCCGGTCTTTGA
TTCAGAAAATTTTGAGCAACCTGGGGCTTCGGAAGCTGGATAATTTTGCTGCAACACTCTTTATTTGTTTCTTGGTGCAG
CCTCGTTTTCTCCTGACAGTTGGAGGTGTCTTGACATTTACCTATGCTTTTTTGTTGACAGTCTTTGATTTTGAGGATTT
GAAGCAAATCAAAAAGGTTGTAGTGGAAAGTCTGAGTATTTCTCTGGGGATTCTGCCAATTCTGATGACCTATTTTTACG
CTTTTCAGCCCCTATCTATTCTACTAACCTTCTTCTTTTCCTTTGTTTTTGATGTATTGCTTTTGCCGAGTCTATCTGTA
ATTTTTCTTTTATCTCCCTTGGTCAAGATTACTTGGGTCAATTCTTTCTTTGTTTTGATGGAGAAAATGATTATTTGGGT
ATCGGATTTGGGTTTTCGGCCTTTGATACTAGGGAAACCGTCTGATTTCATCTTGTTAGTCTTATTACTGGGATTTTTCA
TGCTTTACGATTTTCATAGACAGAAAAAATGGCTATTAGGACTGAGTTTGCTCCTTACTCTGCTATTTTTCATTACAAAA
CATCCATTAGAAAATGAAGTAACTGTGGTAGATATCGGACAGGGAGATAGTATCTTTTTGCGAGATATGCAGGGGCGTAC
GGTTCTAATTGACGTTGGTGGACGGGTGGATTTTACGGTCAAGGAAGGCTGGAAGGCGCGATCCCGTCAGGCTAATGCAG
AGAGAACCTTGATTCCTTATCTACATAGTCGAGGTGTGGACAAGATTGACAGTTTGGTGTTGACGCACACCGATACTGAC
CATGTGGGCGATGTTCTGGAAGTAGCTAAGAATTTTAAGATCGGAAAAATCTATGTGTCTTCAGGTAGTTTGACAGTCCC
TAGCTTTGTAACCACCTTGAAAAAAATCAATGTACCTGTTCATGTGGTGCAGGTGGGTGATCGCCTACCGATTGTTGATT
CCTATTTGGAAGTGCTCTATCCGAGCCGATCGGGTGATGGTAGCAACAATGATTCTATTGTCCTCTATGGACGGCTCCTT
GGAATCAATTTTCTGTTTACGGGTGATCTGGAGGAGGGGGAATTAGAGCTGATAAAAACCTATCCCAAATTGTCAGTTGA
TGTTCTAAAAGCCGGACACCATGGTTCAAAAGGTTCTTCTTATCCTGAATTTTTAGACCATATTGGAGCTAAGATTGCCT
TAATCTCGGCTGGCGAGAAAAATCGCTACAAGCATCCCCATCAAGAAACCTTGGAGCGTTTTGAACAGAAGAATATGCAA
ATCTATCGGACAGACCGGCAAGGAGCTATTCGCTTTAGAGGTTGGCGAAGTTGGTCAATTGAAACGGTGAGATGA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (31-176)

• Metallo-beta-lactamase superfamily (Lactamase_B) (493-697)

• Competence protein (Competence) (215-459)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	53.548	100	0.538
comEC/celB	Streptococcus mitis NCTC 12261	52.965	99.731	0.528
comEC/celB	Streptococcus pneumoniae TIGR4	51.817	99.866	0.517
comEC/celB	Streptococcus pneumoniae Rx1	51.279	99.866	0.512
comEC/celB	Streptococcus pneumoniae D39	51.279	99.866	0.512
comEC/celB	Streptococcus pneumoniae R6	51.279	99.866	0.512
comEC	Lactococcus lactis subsp. cremoris KW2	47.368	99.597	0.472