Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   L6411_RS03980 Genome accession   NZ_AP025333
Coordinates   825576..826250 (+) Length   224 a.a.
NCBI ID   WP_120171596.1    Uniprot ID   -
Organism   Streptococcus ruminantium strain GUT-189     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 820576..831250
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L6411_RS03955 (GUT189_07360) pstC 821149..822066 (+) 918 WP_120171594.1 phosphate ABC transporter permease subunit PstC -
  L6411_RS03960 (GUT189_07370) pstA 822056..822943 (+) 888 WP_024531693.1 phosphate ABC transporter permease PstA -
  L6411_RS03965 (GUT189_07380) pstB 822969..823772 (+) 804 WP_024531694.1 phosphate ABC transporter ATP-binding protein PstB -
  L6411_RS03970 (GUT189_07390) pstB 823784..824542 (+) 759 WP_024531695.1 phosphate ABC transporter ATP-binding protein PstB -
  L6411_RS03975 (GUT189_07400) phoU 824572..825228 (+) 657 WP_024531696.1 phosphate signaling complex protein PhoU -
  L6411_RS03980 (GUT189_07410) ciaR 825576..826250 (+) 675 WP_120171596.1 response regulator transcription factor Regulator
  L6411_RS03985 (GUT189_07420) ciaH 826243..827613 (+) 1371 WP_155963845.1 sensor histidine kinase Regulator
  L6411_RS03990 (GUT189_07430) - 827784..828548 (+) 765 WP_237374429.1 hypothetical protein -
  L6411_RS03995 (GUT189_07440) - 828548..829735 (+) 1188 WP_237374430.1 DUF1266 domain-containing protein -
  L6411_RS04000 (GUT189_07450) rpsT 830024..830272 (-) 249 WP_075098301.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25416.23 Da        Isoelectric Point: 4.2606

>NTDB_id=91242 L6411_RS03980 WP_120171596.1 825576..826250(+) (ciaR) [Streptococcus ruminantium strain GUT-189]
MIKILLIEDDLSLSNSVFDFLDDFADVMQVFDGEEGIYEAEMGIYDLILLDLMLPEKDGFQVLKELREKGVVTPVLITTA
KESLEDKGHGFELGADDYLIKPFYLEELKMRIQALLKRAGKFNEESTLSFGDILVDLSTNTTTVNGQPVELLGKEFDLLV
YFLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKVRKKLKGTAFGEHLQTLRSVGYILKND

Nucleotide


Download         Length: 675 bp        

>NTDB_id=91242 L6411_RS03980 WP_120171596.1 825576..826250(+) (ciaR) [Streptococcus ruminantium strain GUT-189]
ATGATTAAAATCTTATTGATAGAAGATGATTTGAGTCTATCCAATTCAGTCTTTGATTTTTTGGATGACTTTGCAGATGT
CATGCAAGTCTTTGATGGCGAAGAAGGAATCTATGAAGCAGAGATGGGGATTTACGATTTGATTCTCTTAGACTTGATGT
TGCCTGAAAAGGATGGTTTCCAAGTATTGAAAGAGTTACGTGAGAAGGGTGTGGTAACGCCAGTTCTCATCACTACAGCT
AAAGAAAGCTTGGAAGATAAAGGTCATGGTTTTGAATTGGGAGCAGATGATTACCTCATTAAGCCATTTTACTTAGAGGA
GCTGAAAATGCGCATTCAAGCCCTATTAAAACGGGCTGGTAAATTTAATGAGGAAAGCACACTGAGTTTTGGAGATATCT
TAGTTGATTTGTCCACGAATACGACAACCGTGAATGGTCAACCAGTTGAATTGCTGGGGAAAGAATTTGATTTGCTAGTC
TACTTCCTACAGAATCAGAATGTTATTCTGCCTAAAACACAAATTTTTGATCGCATTTGGGGATTTGACAGTGACACTAC
CATTTCAGTCGTTGAAGTCTACGTATCTAAGGTTCGGAAAAAATTGAAAGGGACGGCTTTTGGGGAACATCTTCAAACCC
TTCGTAGTGTCGGTTATATTTTGAAGAATGACTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(146-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

86.547

99.554

0.862
  ciaR Streptococcus pneumoniae D39

86.547

99.554

0.862
  ciaR Streptococcus pneumoniae R6

86.547

99.554

0.862
  ciaR Streptococcus pneumoniae TIGR4

86.547

99.554

0.862
  ciaR Streptococcus mutans UA159

84.753

99.554

0.844
  vicR Streptococcus mutans UA159

34.322

100

0.362

Multiple sequence alignment