Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   L6411_RS03985 Genome accession   NZ_AP025333
Coordinates   826243..827613 (+) Length   456 a.a.
NCBI ID   WP_155963845.1    Uniprot ID   -
Organism   Streptococcus ruminantium strain GUT-189     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 821243..832613
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L6411_RS03960 (GUT189_07370) pstA 822056..822943 (+) 888 WP_024531693.1 phosphate ABC transporter permease PstA -
  L6411_RS03965 (GUT189_07380) pstB 822969..823772 (+) 804 WP_024531694.1 phosphate ABC transporter ATP-binding protein PstB -
  L6411_RS03970 (GUT189_07390) pstB 823784..824542 (+) 759 WP_024531695.1 phosphate ABC transporter ATP-binding protein PstB -
  L6411_RS03975 (GUT189_07400) phoU 824572..825228 (+) 657 WP_024531696.1 phosphate signaling complex protein PhoU -
  L6411_RS03980 (GUT189_07410) ciaR 825576..826250 (+) 675 WP_120171596.1 response regulator transcription factor Regulator
  L6411_RS03985 (GUT189_07420) ciaH 826243..827613 (+) 1371 WP_155963845.1 sensor histidine kinase Regulator
  L6411_RS03990 (GUT189_07430) - 827784..828548 (+) 765 WP_237374429.1 hypothetical protein -
  L6411_RS03995 (GUT189_07440) - 828548..829735 (+) 1188 WP_237374430.1 DUF1266 domain-containing protein -
  L6411_RS04000 (GUT189_07450) rpsT 830024..830272 (-) 249 WP_075098301.1 30S ribosomal protein S20 -
  L6411_RS04005 (GUT189_07460) coaA 830331..831251 (-) 921 WP_024531701.1 type I pantothenate kinase -
  L6411_RS04010 (GUT189_07470) - 831364..831954 (+) 591 WP_237374431.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 456 a.a.        Molecular weight: 51983.78 Da        Isoelectric Point: 7.3167

>NTDB_id=91243 L6411_RS03985 WP_155963845.1 826243..827613(+) (ciaH) [Streptococcus ruminantium strain GUT-189]
MTKRFRKLVYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYENSDDTLHRIKEEPAMAVGLAVARAYQPNSELTLQD
NSNRNTTASILDDTMTPQSGNGEQLRLGVNTHVLLYNKNGEIINPDKFTGLSRLTLDKENLDEIRETTVKSSFGLNENYR
YVTIKLVVEELGRYAVYDIKYATILVNVSQIKSSIEKYEATVAVVMVSAWLISILASIYLSNLSMRPILTSYQKQKDFVE
NASHELRTPLAVLQNRLEGLFRHPETTILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGFKLDMVEVPPTYFDEIFDN
YIIIAEENGKKVTINNLISQSIRTDKVLIKQLLTILFDNAMKYTDDDCDIQITASIKDKLVCFTIADNGLGITDNDKKKI
FDRFYRVDKARTRQKGGFGLGLSLAQQIIKALNGEIFVRDNQPKGTVFEVQLPIKK

Nucleotide


Download         Length: 1371 bp        

>NTDB_id=91243 L6411_RS03985 WP_155963845.1 826243..827613(+) (ciaH) [Streptococcus ruminantium strain GUT-189]
ATGACTAAGCGATTTAGAAAGCTAGTTTACACGGATAAATTTTCTTTCTTTATCCGCTATTTTGCAGTCTTTACTCTGAT
TTTTGGTCTGATGACAGCTATCATCTTTCAATTGATGCGTTCAACCATGTATGAAAATTCGGATGACACGCTACATCGAA
TCAAAGAAGAACCTGCAATGGCAGTTGGACTGGCAGTGGCGAGAGCCTATCAACCGAATTCAGAACTCACTCTCCAAGAC
AATTCAAATAGGAATACGACAGCTTCCATTTTGGATGATACGATGACGCCCCAAAGCGGAAATGGGGAACAATTGAGGTT
GGGAGTGAATACTCACGTACTGCTGTATAACAAGAATGGTGAAATCATTAACCCTGATAAATTCACCGGCTTATCAAGGT
TGACCTTAGACAAGGAAAATTTAGATGAAATTAGGGAAACGACCGTTAAATCTTCTTTTGGACTGAATGAAAATTATCGT
TATGTAACGATTAAACTGGTAGTCGAGGAACTCGGTCGTTATGCGGTTTACGATATAAAGTATGCAACTATCCTAGTGAA
TGTTAGCCAAATTAAATCATCTATTGAGAAGTATGAAGCAACAGTTGCTGTTGTAATGGTTTCTGCTTGGTTGATTTCTA
TCTTGGCAAGTATTTACTTGTCCAATCTTAGTATGCGTCCTATTTTGACTAGCTATCAGAAACAAAAGGATTTTGTGGAA
AATGCCAGTCATGAGCTACGTACACCATTAGCTGTTTTACAGAACCGCTTGGAAGGGTTGTTCCGTCATCCTGAAACGAC
CATTTTGGAAAGTAGCGAAAGTATCGGATCTAGTTTGGAGGAGGTCCGCAATATGCGGTTACTGACGACCAATTTGCTCA
ATCTCGCACGCCGGGATGATGGTTTTAAACTAGATATGGTAGAAGTACCTCCTACCTATTTTGATGAAATATTTGATAAC
TATATTATAATTGCTGAAGAAAACGGCAAGAAGGTGACTATCAACAATTTAATTAGCCAGTCTATTCGAACGGACAAAGT
TTTAATTAAGCAATTGCTGACTATCTTATTTGATAATGCAATGAAATACACCGATGATGATTGCGATATTCAAATTACAG
CCAGTATAAAAGATAAATTAGTCTGCTTTACCATTGCGGATAATGGCTTAGGAATTACCGACAACGACAAAAAGAAAATA
TTTGATCGTTTCTATCGGGTTGATAAGGCTAGAACACGTCAAAAGGGTGGATTCGGTCTAGGCTTATCTTTGGCGCAGCA
GATTATCAAGGCTCTGAATGGAGAAATTTTCGTTAGGGATAATCAGCCTAAAGGGACTGTTTTTGAGGTGCAACTTCCAA
TCAAAAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(235-301)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(345-454)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

49.781

100

0.498
  ciaH Streptococcus pneumoniae D39

49.781

100

0.498
  ciaH Streptococcus pneumoniae R6

49.781

100

0.498
  ciaH Streptococcus pneumoniae TIGR4

49.781

100

0.498
  ciaH Streptococcus mutans UA159

48.786

99.342

0.485

Multiple sequence alignment