Detailed information NTG0091203

Bioinformatically predicted

Overview

• Name: mecA
• Type: Regulator
• Locus tag: L6419_RS08320
• Genome accession: NZ_AP025332
• Coordinates: 1757538..1758260 (-)
• Length: 240 a.a.
• NCBI ID: WP_237375320.1
• Uniprot ID: -
• Organism: Streptococcus ruminantium strain GUT-184
• Function: degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 1752538..1763260

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L6419_RS08295 (GUT184_16010)	sufU	1752581..1753021 (-)	441	WP_120172171.1	Fe-S cluster assembly sulfur transfer protein SufU	-
L6419_RS08300 (GUT184_16020)	-	1753008..1754234 (-)	1227	WP_024531876.1	cysteine desulfurase	-
L6419_RS08305 (GUT184_16030)	sufD	1754236..1755498 (-)	1263	WP_024531875.1	Fe-S cluster assembly protein SufD	-
L6419_RS08310 (GUT184_16040)	sufC	1755515..1756288 (-)	774	WP_024531874.1	Fe-S cluster assembly ATPase SufC	-
L6419_RS08315 (GUT184_16050)	-	1756381..1757541 (-)	1161	WP_120172178.1	glycosyltransferase family 4 protein	-
L6419_RS08320 (GUT184_16060)	mecA	1757538..1758260 (-)	723	WP_237375320.1	adaptor protein MecA	Regulator
L6419_RS08325 (GUT184_16070)	-	1758471..1759307 (-)	837	WP_155964977.1	undecaprenyl-diphosphate phosphatase	-
L6419_RS08330 (GUT184_16080)	-	1759440..1761002 (+)	1563	WP_156021675.1	ABC transporter substrate-binding protein/permease	-
L6419_RS08335 (GUT184_16090)	-	1760995..1761738 (+)	744	WP_024531869.1	amino acid ABC transporter ATP-binding protein	-
L6419_RS08340 (GUT184_16100)	-	1761984..1762193 (-)	210	WP_024531868.1	hypothetical protein	-
L6419_RS08345 (GUT184_16110)	-	1762279..1763178 (-)	900	WP_024531867.1	SPFH domain-containing protein	-

Sequence

Protein

• Length: 240 a.a.
• Molecular weight: 28003.58 Da
• Isoelectric Point: 4.0877

>NTDB_id=91203 L6419_RS08320 WP_237375320.1 1757538..1758260(-) (mecA) [Streptococcus ruminantium strain GUT-184]
MKVKQISDSTLKITIKLDDLEERGMELSDFLIPQEKTEEFFYTVLDELDLPMTFRESGMLSFRVTPKPDRVDIFVTKSDL
DQNLNFDEFTDLSDLGDVASMTPDEFFKSLEQTVREKSAADVAAVQHLEDIEQAEEDEDGEQERYIYYILEFKKIEELFI
FVGTVDYSIEESELYKMDGYYYLTVLVDIENRSKQYPEHLLSRMLEFSNDTKLARPVLQEHGMLLLSHAAIEELRKVTIA

Nucleotide

• Length: 723 bp

>NTDB_id=91203 L6419_RS08320 WP_237375320.1 1757538..1758260(-) (mecA) [Streptococcus ruminantium strain GUT-184]
ATGAAAGTAAAACAAATTAGTGATTCTACCTTAAAAATCACTATCAAATTGGATGACTTGGAAGAAAGAGGCATGGAACT
TTCTGACTTTCTTATCCCACAGGAGAAGACAGAAGAGTTTTTCTACACAGTTCTGGATGAGCTGGACTTGCCGATGACTT
TCCGCGAAAGTGGTATGCTGAGTTTCCGTGTGACACCAAAGCCTGATAGGGTTGACATTTTTGTGACCAAATCTGATTTG
GATCAAAATTTGAATTTTGATGAATTTACAGATTTGTCTGACCTTGGTGATGTTGCCAGCATGACTCCAGATGAATTTTT
CAAGAGTTTGGAGCAGACGGTCCGTGAGAAGAGTGCCGCAGATGTAGCTGCTGTCCAACATCTAGAAGATATTGAGCAGG
CAGAAGAGGATGAGGACGGAGAGCAAGAACGGTATATCTACTATATTTTAGAGTTCAAAAAGATTGAAGAACTGTTTATT
TTTGTTGGTACGGTTGACTATTCGATTGAAGAATCGGAACTTTATAAGATGGATGGTTACTATTATCTGACAGTTCTTGT
TGATATAGAAAACCGTTCCAAGCAATATCCAGAGCACCTTCTTTCACGTATGTTAGAGTTTTCCAACGATACAAAATTAG
CAAGACCTGTCTTGCAAGAACACGGGATGCTCCTCCTCTCCCATGCAGCGATTGAAGAGCTTAGAAAGGTTACAATAGCA
TGA

Domains

Predicted by InterproScan.

• Negative regulator of genetic competence (MecA) (MecA) (1-234)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
mecA	Streptococcus pneumoniae Rx1	55.738	100	0.567
mecA	Streptococcus pneumoniae D39	55.738	100	0.567
mecA	Streptococcus pneumoniae R6	55.738	100	0.567
mecA	Streptococcus pneumoniae TIGR4	55.738	100	0.567
mecA	Streptococcus mutans UA159	50	100	0.508
mecA	Streptococcus thermophilus LMD-9	46.185	100	0.479
mecA	Streptococcus thermophilus LMG 18311	45.783	100	0.475