Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   L6419_RS06485 Genome accession   NZ_AP025332
Coordinates   1346714..1347388 (-) Length   224 a.a.
NCBI ID   WP_120171596.1    Uniprot ID   -
Organism   Streptococcus ruminantium strain GUT-184     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1341714..1352388
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L6419_RS06465 (GUT184_12370) rpsT 1342691..1342939 (+) 249 WP_075098301.1 30S ribosomal protein S20 -
  L6419_RS06470 (GUT184_12380) - 1343228..1344415 (-) 1188 WP_237375196.1 DUF1266 domain-containing protein -
  L6419_RS06475 (GUT184_12390) - 1344415..1345179 (-) 765 WP_237375198.1 hypothetical protein -
  L6419_RS06480 (GUT184_12400) ciaH 1345351..1346721 (-) 1371 WP_155963845.1 sensor histidine kinase Regulator
  L6419_RS06485 (GUT184_12410) ciaR 1346714..1347388 (-) 675 WP_120171596.1 response regulator transcription factor Regulator
  L6419_RS06490 (GUT184_12420) phoU 1347736..1348392 (-) 657 WP_024531696.1 phosphate signaling complex protein PhoU -
  L6419_RS06495 (GUT184_12430) pstB 1348422..1349180 (-) 759 WP_024531695.1 phosphate ABC transporter ATP-binding protein PstB -
  L6419_RS06500 (GUT184_12440) pstB 1349192..1349995 (-) 804 WP_024531694.1 phosphate ABC transporter ATP-binding protein PstB -
  L6419_RS06505 (GUT184_12450) pstA 1350021..1350908 (-) 888 WP_024531693.1 phosphate ABC transporter permease PstA -
  L6419_RS06510 (GUT184_12460) pstC 1350898..1351815 (-) 918 WP_120171594.1 phosphate ABC transporter permease subunit PstC -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25416.23 Da        Isoelectric Point: 4.2606

>NTDB_id=91190 L6419_RS06485 WP_120171596.1 1346714..1347388(-) (ciaR) [Streptococcus ruminantium strain GUT-184]
MIKILLIEDDLSLSNSVFDFLDDFADVMQVFDGEEGIYEAEMGIYDLILLDLMLPEKDGFQVLKELREKGVVTPVLITTA
KESLEDKGHGFELGADDYLIKPFYLEELKMRIQALLKRAGKFNEESTLSFGDILVDLSTNTTTVNGQPVELLGKEFDLLV
YFLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKVRKKLKGTAFGEHLQTLRSVGYILKND

Nucleotide


Download         Length: 675 bp        

>NTDB_id=91190 L6419_RS06485 WP_120171596.1 1346714..1347388(-) (ciaR) [Streptococcus ruminantium strain GUT-184]
ATGATTAAAATCTTATTGATAGAAGATGATTTGAGTCTATCCAATTCAGTCTTTGATTTTTTGGATGACTTTGCAGATGT
CATGCAAGTCTTTGATGGCGAAGAAGGAATCTATGAAGCAGAGATGGGGATTTACGATTTGATTCTCTTAGACTTGATGT
TGCCTGAAAAGGATGGTTTCCAAGTATTGAAAGAGTTACGTGAGAAGGGTGTGGTAACGCCAGTTCTCATCACTACAGCT
AAAGAAAGCTTGGAAGATAAAGGTCATGGTTTTGAATTGGGAGCAGATGATTACCTCATTAAGCCATTTTACTTAGAGGA
GCTGAAAATGCGCATTCAAGCCCTATTAAAACGGGCTGGTAAATTTAATGAGGAAAGCACACTGAGTTTTGGAGATATCT
TAGTTGATTTGTCCACGAATACGACAACCGTGAATGGTCAACCAGTTGAACTGCTGGGGAAAGAATTTGATTTGTTAGTC
TACTTCCTACAGAATCAGAATGTTATTCTGCCTAAAACACAAATTTTTGATCGCATTTGGGGATTTGACAGTGACACTAC
CATTTCAGTCGTTGAAGTCTACGTATCTAAGGTCCGGAAAAAATTGAAAGGGACGGCTTTTGGGGAACATCTTCAAACCC
TTCGTAGTGTCGGTTATATTTTGAAGAATGACTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(146-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

86.547

99.554

0.862
  ciaR Streptococcus pneumoniae D39

86.547

99.554

0.862
  ciaR Streptococcus pneumoniae R6

86.547

99.554

0.862
  ciaR Streptococcus pneumoniae TIGR4

86.547

99.554

0.862
  ciaR Streptococcus mutans UA159

84.753

99.554

0.844
  vicR Streptococcus mutans UA159

34.322

100

0.362

Multiple sequence alignment