Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   L6419_RS06480 Genome accession   NZ_AP025332
Coordinates   1345351..1346721 (-) Length   456 a.a.
NCBI ID   WP_155963845.1    Uniprot ID   -
Organism   Streptococcus ruminantium strain GUT-184     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1340351..1351721
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L6419_RS06455 (GUT184_12350) - 1341009..1341599 (-) 591 WP_155962909.1 class I SAM-dependent methyltransferase -
  L6419_RS06460 (GUT184_12360) coaA 1341712..1342632 (+) 921 WP_156018119.1 type I pantothenate kinase -
  L6419_RS06465 (GUT184_12370) rpsT 1342691..1342939 (+) 249 WP_075098301.1 30S ribosomal protein S20 -
  L6419_RS06470 (GUT184_12380) - 1343228..1344415 (-) 1188 WP_237375196.1 DUF1266 domain-containing protein -
  L6419_RS06475 (GUT184_12390) - 1344415..1345179 (-) 765 WP_237375198.1 hypothetical protein -
  L6419_RS06480 (GUT184_12400) ciaH 1345351..1346721 (-) 1371 WP_155963845.1 sensor histidine kinase Regulator
  L6419_RS06485 (GUT184_12410) ciaR 1346714..1347388 (-) 675 WP_120171596.1 response regulator transcription factor Regulator
  L6419_RS06490 (GUT184_12420) phoU 1347736..1348392 (-) 657 WP_024531696.1 phosphate signaling complex protein PhoU -
  L6419_RS06495 (GUT184_12430) pstB 1348422..1349180 (-) 759 WP_024531695.1 phosphate ABC transporter ATP-binding protein PstB -
  L6419_RS06500 (GUT184_12440) pstB 1349192..1349995 (-) 804 WP_024531694.1 phosphate ABC transporter ATP-binding protein PstB -
  L6419_RS06505 (GUT184_12450) pstA 1350021..1350908 (-) 888 WP_024531693.1 phosphate ABC transporter permease PstA -

Sequence

Protein


Download         Length: 456 a.a.        Molecular weight: 51983.78 Da        Isoelectric Point: 7.3167

>NTDB_id=91189 L6419_RS06480 WP_155963845.1 1345351..1346721(-) (ciaH) [Streptococcus ruminantium strain GUT-184]
MTKRFRKLVYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYENSDDTLHRIKEEPAMAVGLAVARAYQPNSELTLQD
NSNRNTTASILDDTMTPQSGNGEQLRLGVNTHVLLYNKNGEIINPDKFTGLSRLTLDKENLDEIRETTVKSSFGLNENYR
YVTIKLVVEELGRYAVYDIKYATILVNVSQIKSSIEKYEATVAVVMVSAWLISILASIYLSNLSMRPILTSYQKQKDFVE
NASHELRTPLAVLQNRLEGLFRHPETTILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGFKLDMVEVPPTYFDEIFDN
YIIIAEENGKKVTINNLISQSIRTDKVLIKQLLTILFDNAMKYTDDDCDIQITASIKDKLVCFTIADNGLGITDNDKKKI
FDRFYRVDKARTRQKGGFGLGLSLAQQIIKALNGEIFVRDNQPKGTVFEVQLPIKK

Nucleotide


Download         Length: 1371 bp        

>NTDB_id=91189 L6419_RS06480 WP_155963845.1 1345351..1346721(-) (ciaH) [Streptococcus ruminantium strain GUT-184]
ATGACTAAGCGATTTAGAAAGCTAGTTTACACGGATAAATTTTCTTTCTTTATCCGCTATTTTGCAGTCTTTACTCTGAT
TTTTGGTCTGATGACAGCTATCATCTTTCAATTGATGCGTTCAACCATGTATGAAAATTCGGATGACACGCTACATCGAA
TCAAAGAAGAACCTGCAATGGCAGTTGGACTGGCAGTGGCGAGAGCCTATCAACCGAATTCAGAACTCACTCTCCAAGAC
AATTCAAATAGGAATACGACGGCTTCCATTTTGGATGATACGATGACGCCCCAAAGCGGAAATGGGGAACAATTGAGGTT
GGGAGTGAATACTCACGTACTGCTGTATAACAAGAATGGTGAAATCATTAACCCTGATAAATTCACCGGCTTATCAAGGT
TGACCTTAGACAAGGAAAATTTAGATGAAATTAGGGAAACGACCGTTAAATCTTCTTTTGGTTTGAATGAAAATTATCGT
TATGTAACGATTAAACTGGTAGTCGAGGAACTCGGTCGTTATGCGGTTTACGATATAAAGTATGCAACTATCCTAGTGAA
TGTTAGCCAAATTAAATCATCTATTGAGAAGTATGAAGCAACAGTTGCTGTTGTAATGGTTTCTGCTTGGTTGATTTCTA
TCTTGGCAAGTATTTACTTGTCCAATCTTAGTATGCGTCCTATTTTGACTAGCTATCAGAAACAAAAGGATTTTGTGGAA
AATGCCAGTCATGAGCTACGTACACCATTAGCTGTTTTACAGAACCGCTTGGAAGGGTTGTTCCGTCATCCTGAAACGAC
CATTTTGGAAAGTAGCGAAAGTATCGGATCTAGTTTGGAGGAGGTCCGCAATATGCGGTTACTGACGACCAATTTGCTCA
ATCTCGCACGCCGGGATGATGGTTTTAAACTAGATATGGTAGAAGTACCTCCTACCTATTTTGATGAAATATTTGATAAC
TATATTATAATTGCTGAAGAAAACGGCAAGAAGGTGACTATCAACAATTTAATTAGCCAGTCTATTCGAACGGACAAAGT
TTTAATTAAGCAATTGCTGACTATCTTATTTGATAATGCAATGAAATACACCGATGATGATTGCGATATTCAAATTACAG
CCAGTATAAAAGATAAATTAGTCTGCTTTACCATTGCGGATAATGGCTTAGGAATTACCGACAACGACAAAAAGAAAATA
TTTGATCGTTTCTATCGGGTTGATAAGGCTAGAACACGTCAAAAGGGTGGATTCGGTCTAGGCTTATCTTTGGCGCAGCA
GATTATCAAGGCTCTGAATGGAGAAATTTTCGTTAGGGATAATCAGCCTAAAGGGACTGTTTTTGAGGTGCAACTTCCAA
TCAAAAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(235-301)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(345-454)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

49.781

100

0.498
  ciaH Streptococcus pneumoniae D39

49.781

100

0.498
  ciaH Streptococcus pneumoniae R6

49.781

100

0.498
  ciaH Streptococcus pneumoniae TIGR4

49.781

100

0.498
  ciaH Streptococcus mutans UA159

48.786

99.342

0.485

Multiple sequence alignment