Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   L6419_RS05905 Genome accession   NZ_AP025332
Coordinates   1227641..1229791 (-) Length   716 a.a.
NCBI ID   WP_237375152.1    Uniprot ID   -
Organism   Streptococcus ruminantium strain GUT-184     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1222641..1234791
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L6419_RS05885 (GUT184_11210) - 1224157..1224792 (-) 636 WP_237375150.1 hypothetical protein -
  L6419_RS05890 (GUT184_11220) - 1225371..1226120 (-) 750 WP_024381039.1 LytTR family transcriptional regulator DNA-binding domain-containing protein -
  L6419_RS05895 (GUT184_11230) - 1226135..1227004 (-) 870 WP_226313481.1 GHKL domain-containing protein -
  L6419_RS05900 (GUT184_11240) - 1227464..1227619 (-) 156 WP_000794567.1 hypothetical protein -
  L6419_RS05905 (GUT184_11250) comA 1227641..1229791 (-) 2151 WP_237375152.1 peptide cleavage/export ABC transporter Regulator
  L6419_RS05910 (GUT184_11260) - 1229994..1230185 (-) 192 WP_105141509.1 hypothetical protein -
  L6419_RS05915 (GUT184_11270) - 1230274..1230546 (-) 273 WP_237375153.1 DUF3884 family protein -
  L6419_RS05920 (GUT184_11280) - 1230575..1231891 (-) 1317 WP_237375155.1 glycosyltransferase family 2 protein -
  L6419_RS05925 (GUT184_11290) - 1232082..1232240 (-) 159 Protein_1128 putative cross-wall-targeting lipoprotein signal domain-containing proteiin -
  L6419_RS05930 (GUT184_11300) - 1232511..1233104 (-) 594 WP_237375157.1 PBECR4 domain-containing protein -

Sequence

Protein


Download         Length: 716 a.a.        Molecular weight: 81599.42 Da        Isoelectric Point: 6.7818

>NTDB_id=91186 L6419_RS05905 WP_237375152.1 1227641..1229791(-) (comA) [Streptococcus ruminantium strain GUT-184]
MKFSKRHYRAQVDSKDCGVAALAMVLEYYNSHYSLAELREMLGTTENGTTAFSIVSVANELGFDTEAIYADISLFDIEDI
KFPFIVHINKNNKFYHYYVIIGSDKKYIYIADPDPLIKLSKLTKEQFLAEWRGITILLKPNHEYKIKIKKTSFPSLFTLL
FNQKKLIFLIILLTLAVNFINIIGSYYLKRVIDSYIPKGELDFLNLMSISLIVIYLMQQFFVFGQGVLITVLSQILSKNI
MLSYIAHLFKLPLSFFATRRTGDIVSRFSDANIIIEVLSSIILSVILDVSIVTGVSIVLFLQSSYLFFIIIIAFPIYALV
IFLFMKPFRRSKTSVMEAGASLSSVLIEDINGIETIKSLTSEVDRYKKIKDEFSNYYKKITFYSRMELFQDVLKKFTQLL
FNVLILWQGAILVIEGKISLGSLITFNTLELYFLNSLENIINLQPKFQSASVAYNRLEEIYSVQSEFQDKFFITNFKLNS
SKIVISNLTYKYGYNQPLLKDINLVIEEGCKIAFVGLSGSGKTTLAKMLVNFMPPTYGSIEFGGININDIDKKTLRQLIN
YIPQKPYIFNGTILDNLLLGVEDEISFEEINKATEIAEIKSVIENLPFGYETELSTEHSILSGGQLQRVAIARALLTNPS
VLILDESTSNLDNLTERKIIDNLMSLDATVIFIAHRLNITEQVERIFVIENGMIIENGNHEDLILKQGFYSKILKG

Nucleotide


Download         Length: 2151 bp        

>NTDB_id=91186 L6419_RS05905 WP_237375152.1 1227641..1229791(-) (comA) [Streptococcus ruminantium strain GUT-184]
ATGAAATTTTCGAAACGTCATTATCGTGCTCAAGTTGATTCAAAAGATTGTGGAGTAGCTGCTTTGGCCATGGTGTTAGA
ATACTATAATTCACATTATTCTTTAGCAGAACTTAGAGAAATGTTAGGTACAACTGAAAATGGGACTACTGCATTTAGTA
TAGTTTCTGTGGCAAATGAATTAGGGTTCGATACTGAAGCTATTTATGCAGATATTTCTTTATTTGACATAGAGGATATA
AAATTTCCATTTATTGTACATATAAATAAGAATAATAAATTTTATCATTACTATGTTATTATTGGCAGTGATAAAAAATA
TATTTATATAGCTGATCCTGATCCTCTGATAAAATTATCTAAACTAACTAAAGAACAGTTTCTTGCAGAATGGAGAGGGA
TAACTATATTATTAAAACCAAACCATGAGTACAAAATTAAAATAAAGAAGACAAGTTTTCCTTCTTTATTTACTTTACTG
TTTAATCAAAAGAAATTAATTTTTTTAATTATATTATTAACTTTAGCAGTAAACTTTATAAATATAATTGGTTCATACTA
TTTAAAGAGAGTAATTGATTCTTATATTCCTAAAGGGGAGCTGGATTTTCTTAATCTAATGTCAATAAGCCTAATTGTTA
TTTATCTTATGCAACAGTTTTTTGTATTTGGTCAAGGGGTATTGATAACAGTTCTAAGTCAAATACTTTCAAAAAATATA
ATGCTGTCATATATTGCTCACCTTTTTAAACTTCCTCTATCTTTTTTTGCAACAAGAAGAACTGGCGATATTGTCTCTAG
ATTTTCAGATGCTAATATCATAATTGAAGTATTATCTAGTATAATTTTATCTGTAATACTAGATGTGTCAATAGTTACTG
GAGTATCAATTGTACTTTTTTTGCAAAGTAGTTATTTATTTTTTATTATAATTATTGCGTTTCCAATTTATGCTTTAGTA
ATTTTTTTATTCATGAAACCATTTAGACGTAGTAAAACTAGTGTAATGGAAGCAGGAGCTTCACTTTCCTCAGTTCTTAT
AGAAGATATAAATGGAATAGAGACAATAAAATCTCTTACTAGTGAGGTTGATCGCTATAAAAAAATAAAAGACGAATTTA
GTAATTATTATAAAAAAATTACTTTTTATAGTAGAATGGAGTTGTTTCAAGATGTGTTAAAAAAATTTACTCAATTGTTG
TTTAATGTATTAATTTTATGGCAAGGTGCTATTTTAGTAATTGAAGGAAAAATATCATTGGGATCTTTGATAACCTTTAA
TACTTTAGAACTTTATTTTCTGAATTCACTGGAGAACATTATTAATTTACAACCTAAATTTCAATCAGCAAGTGTTGCGT
ATAATAGATTAGAAGAAATCTATTCGGTTCAATCGGAATTTCAGGATAAGTTCTTCATAACAAATTTTAAATTGAATTCT
AGTAAGATAGTAATTTCAAATTTAACCTACAAATATGGCTATAACCAGCCTCTATTAAAAGATATTAATTTAGTTATCGA
GGAAGGTTGTAAAATAGCATTTGTTGGTCTTTCTGGTTCAGGGAAAACAACTCTAGCAAAAATGTTAGTTAATTTTATGC
CTCCTACCTATGGAAGTATTGAATTTGGAGGAATTAATATTAATGATATTGATAAGAAGACTTTGAGACAATTGATTAAT
TATATACCCCAGAAACCTTATATTTTTAACGGTACTATATTAGATAATCTTTTATTAGGTGTTGAAGATGAAATTTCATT
TGAAGAGATTAATAAAGCTACTGAGATTGCCGAGATAAAATCTGTTATAGAGAATTTACCGTTTGGATATGAGACCGAAC
TTTCCACTGAACATAGCATTTTGTCAGGAGGTCAACTTCAGAGAGTTGCTATTGCACGTGCATTATTAACCAATCCTTCG
GTATTAATCTTAGATGAGTCAACAAGTAATTTGGATAATTTAACGGAAAGAAAAATTATTGATAATTTAATGAGCTTAGA
TGCAACTGTAATATTTATTGCTCACCGTCTTAATATAACAGAACAGGTTGAAAGGATATTTGTCATAGAAAATGGTATGA
TAATCGAAAACGGAAATCATGAAGATTTGATATTAAAACAAGGGTTTTATTCTAAAATATTAAAAGGTTAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(499-649)

Peptidase C39 family (Peptidase_C39)

(7-142)

ABC transporter transmembrane region (ABC_membrane)

(167-437)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

56.224

99.86

0.561
  comA Streptococcus gordonii str. Challis substr. CH1

56.084

99.86

0.56
  comA Streptococcus mitis SK321

55.664

99.86

0.556
  comA Streptococcus pneumoniae R6

55.385

99.86

0.553
  comA Streptococcus pneumoniae Rx1

55.385

99.86

0.553
  comA Streptococcus pneumoniae D39

55.385

99.86

0.553
  comA Streptococcus pneumoniae TIGR4

55.105

99.86

0.55
  comA/nlmT Streptococcus mutans UA159

49.157

99.441

0.489

Multiple sequence alignment