Detailed information NTG0091184

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: L6419_RS04040
• Genome accession: NZ_AP025332
• Coordinates: 809735..811969 (+)
• Length: 744 a.a.
• NCBI ID: WP_237375687.1
• Uniprot ID: -
• Organism: Streptococcus ruminantium strain GUT-184
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 804735..816969

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L6419_RS04020 (GUT184_07450)	-	805484..806272 (-)	789	WP_024532634.1	ABC transporter ATP-binding protein	-
L6419_RS04025 (GUT184_07460)	-	806631..808076 (-)	1446	WP_155974169.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-
L6419_RS04030 (GUT184_07470)	-	808267..809010 (+)	744	WP_024532636.1	lysophospholipid acyltransferase family protein	-
L6419_RS04035 (GUT184_07480)	comEA	809095..809751 (+)	657	WP_024532637.1	helix-hairpin-helix domain-containing protein	Machinery gene
L6419_RS04040 (GUT184_07490)	comEC/celB	809735..811969 (+)	2235	WP_237375687.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
L6419_RS04045 (GUT184_07500)	-	812116..812727 (+)	612	WP_228025421.1	hypothetical protein	-
L6419_RS04050 (GUT184_07510)	holA	812983..814014 (+)	1032	WP_237375688.1	DNA polymerase III subunit delta	-
L6419_RS04055 (GUT184_07520)	sodA	814111..814722 (+)	612	WP_024532641.1	superoxide dismutase SodA	-
L6419_RS10045	-	814915..815081 (+)	167	Protein_759	recombinase	-
L6419_RS04060 (GUT184_07530)	-	815351..815974 (+)	624	WP_237375689.1	helix-turn-helix domain-containing protein	-
L6419_RS04065 (GUT184_07540)	-	816101..816265 (+)	165	WP_237375690.1	transposon-encoded TnpW family protein	-

Sequence

Protein

• Length: 744 a.a.
• Molecular weight: 84892.72 Da
• Isoelectric Point: 9.6522

>NTDB_id=91184 L6419_RS04040 WP_237375687.1 809735..811969(+) (comEC/celB) [Streptococcus ruminantium strain GUT-184]
MLRLDKLPCQPIHLAILAVVTYFTVHRFSMLTMSLLILLLVIYWRRQGKLTFFKMLPLLVLCGLFFGCQKLKWKQEEQAV
SKQVTAVEIVPDTININGDQLSFRARTDGQIYQGFYKLTSQKEQEYFQKLTALVQVEVKAETSLPSGQRNFNGFDYQAYL
KTQGIYRILTIAAINKIVPIHSWNPMDWLSIWRRKALVFIKSNFPSPMSHYMTGLLFGELDSDFDQMSALYSSLGIIHLF
ALSGMQVGFFIDKFRWILLRLGLTKETVDQLQVPFSFVYAGLTGFSVSVVRSLIQKILSNLGLRKLDNFAAALFICFLVQ
PRFLLTVGGVLTFTYAFLLTVFDFEDLKQIKKVVVESLSISLGILPILMTYFYAFQPLSILLTFFFSFVFDVLLLPTLSV
IFLLSPLVKITWVNSFFVLMEKMIIWVSDLGFRPLILGKPSDFILLVLLLGFFMLYDFHRQKKWLLGLSLLLALLFFITK
HPLENEVTVVDIGQGDSIFLRDMQGRTVLIDVGGRVDFAAKEDWKARSRQANAERTLIPYLHSRGVDKIDSLVLTHTDTD
HVGDILEVAKNFKIGKIYVSSGSLTVPSFVTTLKKINVPVHVVQVGDRLPIVDSYLEVLYPSRSGDGSNNDSIVLYGRLL
GINFLFTGDLEEGELELIKTYPKLSVDVLKAGHHGSKGSSYPEFLDHIGAKIALISAGEKNRYKHPHQETLERFEQKNMQ
IYRTDRQGAIRFRGWRSWSIETVR

Nucleotide

• Length: 2235 bp

>NTDB_id=91184 L6419_RS04040 WP_237375687.1 809735..811969(+) (comEC/celB) [Streptococcus ruminantium strain GUT-184]
ATGTTACGGTTGGATAAGCTCCCCTGTCAGCCTATACATCTAGCCATTTTGGCGGTCGTGACCTACTTTACGGTTCACCG
TTTTTCGATGTTGACAATGAGCCTTCTGATATTATTATTGGTAATCTATTGGCGGCGTCAGGGGAAACTTACTTTTTTTA
AAATGCTGCCGCTTCTAGTCTTATGCGGTCTATTCTTCGGCTGCCAAAAGCTCAAATGGAAACAGGAAGAGCAAGCTGTT
TCAAAGCAAGTGACTGCTGTAGAGATTGTGCCGGATACTATAAATATCAATGGCGATCAGTTATCTTTCCGTGCTAGGAC
TGATGGTCAGATTTATCAAGGTTTCTATAAGCTAACTAGTCAGAAAGAACAGGAGTATTTCCAAAAGCTAACAGCTCTTG
TTCAGGTGGAGGTGAAGGCAGAGACGAGTCTCCCATCAGGTCAGCGGAATTTCAATGGTTTTGATTATCAAGCCTATTTA
AAAACACAGGGAATCTATCGAATCCTCACCATAGCGGCTATCAATAAGATCGTACCTATTCACTCTTGGAACCCTATGGA
TTGGTTGTCAATTTGGCGGAGAAAAGCCTTGGTTTTCATCAAATCTAATTTTCCTTCCCCCATGAGCCATTACATGACAG
GGTTGCTTTTTGGAGAGTTGGACAGTGACTTTGATCAGATGAGCGCCCTTTACTCCAGTCTGGGGATTATCCATCTCTTT
GCTCTATCAGGAATGCAGGTAGGTTTTTTCATTGATAAGTTTCGCTGGATTTTACTGCGTTTAGGCTTGACAAAGGAGAC
AGTTGATCAATTACAAGTCCCCTTTTCTTTTGTCTATGCTGGTTTGACAGGCTTTTCTGTATCAGTCGTCCGGTCTTTGA
TTCAGAAAATTTTGAGCAACCTGGGGCTTCGGAAGCTGGATAATTTTGCTGCAGCACTCTTTATTTGTTTCTTGGTGCAG
CCTCGTTTTCTCCTGACAGTTGGAGGTGTCTTGACATTTACCTATGCTTTTTTGTTGACGGTCTTTGATTTTGAAGACTT
GAAGCAAATCAAAAAGGTTGTAGTGGAAAGTCTGAGTATTTCTCTGGGGATTCTGCCAATTCTGATGACCTATTTTTACG
CTTTTCAGCCCCTATCTATTCTACTAACCTTCTTCTTTTCCTTTGTTTTTGATGTATTGCTTTTACCGACTCTATCTGTA
ATTTTTCTTTTATCTCCCTTGGTCAAGATTACTTGGGTCAATTCTTTCTTTGTTTTGATGGAGAAAATGATTATTTGGGT
ATCGGATTTGGGTTTTCGGCCTTTGATACTAGGGAAACCGTCTGATTTCATCTTGTTAGTCTTATTACTGGGATTTTTCA
TGCTTTACGATTTTCATAGACAGAAAAAATGGCTATTAGGACTGAGTTTGCTCCTTGCTCTGCTATTTTTCATTACAAAA
CATCCATTAGAAAATGAAGTAACTGTGGTAGATATCGGACAGGGAGATAGTATCTTTTTGCGAGATATGCAGGGGCGTAC
GGTTCTAATTGACGTTGGTGGACGGGTGGATTTTGCGGCTAAGGAAGACTGGAAGGCACGATCCCGTCAGGCTAATGCAG
AGCGGACTTTGATTCCTTATCTACATAGTCGAGGTGTGGACAAGATTGACAGTTTGGTGTTGACGCACACCGATACTGAC
CATGTGGGCGATATTCTGGAAGTGGCTAAGAATTTTAAGATCGGAAAGATCTATGTGTCTTCAGGTAGTTTGACAGTCCC
TAGCTTTGTAACCACCTTGAAAAAAATCAATGTACCTGTTCATGTGGTGCAGGTGGGTGATCGCCTACCGATTGTTGATT
CCTATTTGGAAGTGCTCTATCCGAGCCGATCGGGTGATGGTAGCAACAATGATTCTATTGTCCTTTATGGACGGCTCCTT
GGAATCAATTTTCTGTTTACGGGTGATTTGGAGGAGGGGGAATTAGAGCTGATAAAAACCTATCCCAAATTGTCAGTTGA
TGTTCTAAAAGCCGGACACCATGGTTCAAAAGGTTCTTCTTATCCTGAATTTTTAGACCATATTGGAGCTAAGATTGCCT
TAATCTCGGCTGGTGAGAAAAATCGCTACAAGCATCCCCATCAAGAAACCTTGGAGCGTTTTGAACAGAAGAATATGCAA
ATCTATCGGACAGACCGGCAAGGAGCTATTCGCTTTAGAGGTTGGCGAAGTTGGTCAATTGAAACGGTGAGATGA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (215-459)

• Metallo-beta-lactamase superfamily (Lactamase_B) (493-697)

• Domain of unknown function (DUF4131) (DUF4131) (31-176)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	53.012	100	0.532
comEC/celB	Streptococcus mitis NCTC 12261	52.426	99.731	0.523
comEC/celB	Streptococcus pneumoniae TIGR4	51.144	99.866	0.511
comEC/celB	Streptococcus pneumoniae Rx1	50.74	99.866	0.507
comEC/celB	Streptococcus pneumoniae D39	50.74	99.866	0.507
comEC/celB	Streptococcus pneumoniae R6	50.74	99.866	0.507
comEC	Lactococcus lactis subsp. cremoris KW2	47.233	99.597	0.47