Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   L6419_RS02125 Genome accession   NZ_AP025332
Coordinates   418697..420700 (+) Length   667 a.a.
NCBI ID   WP_024532776.1    Uniprot ID   A0A2Z5TNJ9
Organism   Streptococcus ruminantium strain GUT-184     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 413697..425700
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L6419_RS02110 (GUT184_03800) fmt 415684..416622 (+) 939 WP_156009563.1 methionyl-tRNA formyltransferase -
  L6419_RS02115 (GUT184_03810) rsmB 416609..417922 (+) 1314 WP_156021120.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  L6419_RS02120 (GUT184_03820) - 417960..418697 (+) 738 WP_120171349.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  L6419_RS02125 (GUT184_03830) stkP 418697..420700 (+) 2004 WP_024532776.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  L6419_RS02130 (GUT184_03840) liaF 420903..421598 (+) 696 WP_120172453.1 cell wall-active antibiotics response protein LiaF -
  L6419_RS02135 (GUT184_03850) - 421595..422611 (+) 1017 WP_237375598.1 sensor histidine kinase -
  L6419_RS02140 (GUT184_03860) - 422583..423224 (+) 642 WP_120171351.1 response regulator transcription factor -
  L6419_RS02145 (GUT184_03870) - 423273..424673 (+) 1401 WP_155964758.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  L6419_RS02150 (GUT184_03880) - 424675..425046 (+) 372 WP_024532771.1 S1 RNA-binding domain-containing protein -
  L6419_RS02155 (GUT184_03890) - 425121..425441 (+) 321 WP_120171198.1 transposase -

Sequence

Protein


Download         Length: 667 a.a.        Molecular weight: 71672.63 Da        Isoelectric Point: 8.7178

>NTDB_id=91176 L6419_RS02125 WP_024532776.1 418697..420700(+) (stkP) [Streptococcus ruminantium strain GUT-184]
MIQIGKIFAGRYRIVRQIGRGGMADVYLARDLILDGEEVAVKVLRTNYQTDQIAIQRFQREARAMAELDHPNIVRISDIG
EEDGQQYLAMEYVNGLDLKRYIKENAPLSNDVAVRIVGQILLAMRIAHTRGIVHRDLKPQNVLLTSNGVAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIILFEMLTGRIPYDGDSAVTIALQHFQKPLPSVREENANVP
QALENVVLKATAKKLNERYKSVAEMYADLASALSVERRNEPRVELEGNKVDTKTLPKLSQANVDTKSPMANDSVQNVATD
KSVGKKEGIKKPTKSASKPRPGMRTRYKVLIGAILLTALAAGLMFFNTPKTVIVPDVAGQTVEKATEMIEVAGLEVGNVI
KETTKEVGEGLVIRTSPAAKTTKRQGSKVDIVVAIAALVTIPDVSNKSADLARQELEALGFQVSVKEEYSDKVAQGLVIK
TSPEANSSAEQGGKVVLSVSKGVAPQLVPDVVGKTQENATQILQTAGFSIGTITKEHHPSIEAGHVISTDPVANTELTKG
SPVNIVVSKGKELIMPDLVSGNYTYSQARRQLQALGVNIENIERQEDRSYYSTTSDIVIGQYPAAGAVIDGTVTLYVSVA
ASGTNSNSSTGTPSSTSTSTSGTSNGQ

Nucleotide


Download         Length: 2004 bp        

>NTDB_id=91176 L6419_RS02125 WP_024532776.1 418697..420700(+) (stkP) [Streptococcus ruminantium strain GUT-184]
ATGATTCAAATCGGTAAGATCTTTGCTGGGCGCTATCGGATTGTCCGGCAAATTGGTCGAGGCGGTATGGCGGATGTTTA
TCTGGCTAGAGATTTGATTTTGGATGGTGAAGAAGTGGCGGTTAAGGTACTTCGCACTAACTATCAGACGGATCAAATTG
CTATCCAGCGCTTCCAGCGTGAGGCGCGTGCCATGGCGGAGCTTGACCATCCCAATATTGTTCGTATTTCGGATATTGGT
GAAGAAGATGGTCAGCAATACCTTGCAATGGAGTACGTCAACGGTCTCGATTTAAAACGCTATATCAAGGAAAATGCACC
ACTATCAAATGATGTGGCAGTACGAATCGTAGGACAAATTCTTCTTGCTATGCGGATAGCTCATACACGGGGAATTGTTC
ACAGGGATTTGAAACCTCAAAATGTTCTTTTGACCTCAAACGGTGTAGCTAAGGTAACGGACTTTGGTATCGCAGTAGCT
TTTGCAGAAACAAGCCTGACACAGACAAATTCTATGTTAGGATCTGTTCACTACCTTTCGCCAGAACAGGCACGTGGTTC
AAAAGCGACCATTCAAAGCGATATTTACGCTATGGGGATTATTCTCTTTGAAATGTTGACTGGTCGAATTCCTTACGATG
GAGATAGTGCTGTTACGATTGCATTGCAACATTTTCAAAAGCCATTACCATCTGTTAGAGAAGAAAATGCGAATGTGCCA
CAAGCATTAGAAAATGTAGTTCTGAAGGCAACTGCTAAAAAGTTGAATGAACGCTATAAATCTGTTGCGGAAATGTATGC
AGACTTAGCTTCAGCCTTGTCTGTGGAACGTCGCAATGAACCGCGGGTTGAGTTGGAGGGCAATAAGGTTGACACAAAGA
CCTTGCCTAAACTTTCTCAGGCAAATGTAGATACTAAGTCTCCTATGGCGAATGATTCTGTTCAAAATGTAGCGACAGAT
AAATCTGTTGGAAAGAAAGAGGGAATTAAAAAGCCAACCAAGTCTGCTTCTAAGCCTAGACCAGGTATGCGCACACGTTA
TAAGGTTCTAATAGGAGCTATTCTTTTGACTGCATTGGCAGCAGGGTTGATGTTTTTCAATACACCTAAAACAGTTATAG
TCCCAGATGTAGCAGGCCAAACGGTTGAAAAAGCCACTGAGATGATTGAAGTGGCAGGATTAGAAGTCGGAAATGTCATC
AAGGAAACGACCAAAGAAGTTGGTGAAGGTTTAGTTATACGGACATCACCAGCAGCAAAAACCACCAAACGTCAAGGGAG
CAAAGTGGATATTGTGGTAGCAATAGCTGCCTTGGTCACTATTCCGGATGTTAGTAATAAATCAGCGGACCTTGCTCGTC
AAGAATTGGAAGCTTTAGGTTTCCAAGTGAGTGTCAAAGAGGAGTATAGTGATAAGGTTGCTCAAGGATTAGTAATAAAG
ACAAGTCCTGAAGCGAATAGTTCTGCTGAACAAGGAGGCAAGGTTGTTCTTTCTGTTTCCAAAGGTGTAGCACCCCAACT
AGTGCCTGATGTCGTTGGAAAAACGCAAGAAAATGCCACCCAGATTCTTCAGACAGCAGGTTTTTCTATTGGAACGATTA
CCAAGGAGCATCATCCTTCAATTGAAGCGGGACACGTCATCAGTACAGATCCTGTTGCGAATACGGAATTAACCAAAGGT
TCACCGGTCAATATCGTAGTTTCTAAAGGAAAAGAGCTAATCATGCCTGACTTGGTCTCTGGGAATTACACCTATTCACA
AGCTCGTAGACAATTACAGGCTCTGGGTGTTAACATAGAAAATATTGAAAGGCAAGAAGATAGAAGCTATTACTCAACCA
CCAGTGATATTGTAATTGGACAATATCCGGCTGCTGGAGCAGTTATTGATGGAACGGTTACTCTGTATGTTTCTGTTGCT
GCGAGTGGAACAAACAGCAACTCCTCTACGGGGACACCATCTAGTACCAGTACTTCAACTAGTGGAACGAGTAATGGACA
GTAG

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(372-433)

PASTA domain (PASTA)

(508-569)

PASTA domain (PASTA)

(574-638)

PASTA domain (PASTA)

(439-501)

Protein kinase domain (Pkinase)

(12-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2Z5TNJ9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

52.623

97.151

0.511
  stkP Streptococcus pneumoniae D39

52.469

97.151

0.51
  stkP Streptococcus pneumoniae R6

52.469

97.151

0.51
  stkP Streptococcus pneumoniae Rx1

52.315

97.151

0.508
  stkP/pknB Streptococcus salivarius strain HSISS4

53.298

84.108

0.448
  pknB Streptococcus mutans UA159

55.576

80.66

0.448

Multiple sequence alignment