Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   SUT_RS04310 Genome accession   NZ_AP025331
Coordinates   888777..889451 (+) Length   224 a.a.
NCBI ID   WP_120171596.1    Uniprot ID   -
Organism   Streptococcus ruminantium strain GUT-183     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 883777..894451
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SUT_RS04285 (GUT183_08020) pstC 884350..885267 (+) 918 WP_120171594.1 phosphate ABC transporter permease subunit PstC -
  SUT_RS04290 (GUT183_08030) pstA 885257..886144 (+) 888 WP_024531693.1 phosphate ABC transporter permease PstA -
  SUT_RS04295 (GUT183_08040) pstB 886170..886973 (+) 804 WP_024531694.1 phosphate ABC transporter ATP-binding protein PstB -
  SUT_RS04300 (GUT183_08050) pstB 886985..887743 (+) 759 WP_024531695.1 phosphate ABC transporter ATP-binding protein PstB -
  SUT_RS04305 (GUT183_08060) phoU 887773..888429 (+) 657 WP_024531696.1 phosphate signaling complex protein PhoU -
  SUT_RS04310 (GUT183_08070) ciaR 888777..889451 (+) 675 WP_120171596.1 response regulator transcription factor Regulator
  SUT_RS04315 (GUT183_08080) ciaH 889444..890814 (+) 1371 WP_237373602.1 sensor histidine kinase Regulator
  SUT_RS04320 (GUT183_08090) - 890986..891750 (+) 765 WP_227985742.1 hypothetical protein -
  SUT_RS04325 (GUT183_08100) - 891750..892937 (+) 1188 WP_156019201.1 DUF1266 domain-containing protein -
  SUT_RS04330 (GUT183_08110) rpsT 893226..893474 (-) 249 WP_075098301.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25416.23 Da        Isoelectric Point: 4.2606

>NTDB_id=91137 SUT_RS04310 WP_120171596.1 888777..889451(+) (ciaR) [Streptococcus ruminantium strain GUT-183]
MIKILLIEDDLSLSNSVFDFLDDFADVMQVFDGEEGIYEAEMGIYDLILLDLMLPEKDGFQVLKELREKGVVTPVLITTA
KESLEDKGHGFELGADDYLIKPFYLEELKMRIQALLKRAGKFNEESTLSFGDILVDLSTNTTTVNGQPVELLGKEFDLLV
YFLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKVRKKLKGTAFGEHLQTLRSVGYILKND

Nucleotide


Download         Length: 675 bp        

>NTDB_id=91137 SUT_RS04310 WP_120171596.1 888777..889451(+) (ciaR) [Streptococcus ruminantium strain GUT-183]
ATGATTAAAATCTTATTGATAGAAGATGATTTGAGTCTATCCAATTCAGTCTTTGATTTTTTGGATGACTTTGCAGATGT
CATGCAAGTCTTTGATGGCGAAGAAGGAATCTATGAAGCAGAGATGGGGATTTACGATTTGATTCTCTTAGACTTGATGT
TGCCTGAAAAGGATGGTTTCCAAGTATTAAAAGAGTTACGTGAGAAGGGTGTGGTAACACCAGTTCTCATCACTACAGCT
AAAGAAAGCTTGGAAGATAAAGGTCATGGTTTTGAATTGGGAGCAGATGATTACCTCATTAAGCCATTTTACTTAGAGGA
GCTGAAAATGCGCATTCAAGCCCTATTAAAACGGGCTGGTAAATTTAATGAGGAAAGCACATTGAGTTTTGGAGATATCT
TAGTTGATTTGTCCACGAATACGACAACCGTGAATGGTCAACCAGTTGAATTGCTGGGGAAAGAATTTGATTTGTTAGTC
TACTTCCTACAGAATCAGAATGTTATTCTGCCTAAAACACAAATTTTTGATCGCATTTGGGGATTTGACAGTGACACTAC
CATTTCAGTCGTTGAAGTCTACGTATCTAAGGTTCGGAAAAAATTGAAAGGGACGGCTTTTGGGGAACATCTTCAAACCC
TTCGTAGTGTCGGTTATATTTTGAAGAATGACTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(146-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

86.547

99.554

0.862
  ciaR Streptococcus pneumoniae D39

86.547

99.554

0.862
  ciaR Streptococcus pneumoniae R6

86.547

99.554

0.862
  ciaR Streptococcus pneumoniae TIGR4

86.547

99.554

0.862
  ciaR Streptococcus mutans UA159

84.753

99.554

0.844
  vicR Streptococcus mutans UA159

34.322

100

0.362

Multiple sequence alignment