Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   U0448_RS05185 Genome accession   NZ_CP139860
Coordinates   1017762..1018424 (-) Length   220 a.a.
NCBI ID   WP_000649971.1    Uniprot ID   A0A0B7MFB3
Organism   Streptococcus pneumoniae strain 21011     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1012762..1023424
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0448_RS05160 - 1012912..1013178 (-) 267 WP_001278167.1 Veg family protein -
  U0448_RS05165 dnaB 1013180..1014532 (-) 1353 WP_050137283.1 replicative DNA helicase -
  U0448_RS05170 rplI 1014576..1015028 (-) 453 WP_000864220.1 50S ribosomal protein L9 -
  U0448_RS05175 - 1015025..1016998 (-) 1974 WP_001864876.1 DHH family phosphoesterase -
  U0448_RS05180 hpf 1017134..1017682 (-) 549 WP_000599104.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  U0448_RS05185 comFC/cflB 1017762..1018424 (-) 663 WP_000649971.1 ComF family protein Machinery gene
  U0448_RS05190 comFA/cflA 1018421..1019719 (-) 1299 WP_000867609.1 DEAD/DEAH box helicase Machinery gene
  U0448_RS05195 - 1019775..1020410 (+) 636 WP_000395739.1 YigZ family protein -
  U0448_RS05200 cysK 1020695..1021615 (+) 921 WP_000029866.1 cysteine synthase A -
  U0448_RS05205 - 1021854..1022204 (-) 351 Protein_984 IS66 family transposase -
  U0448_RS05210 - 1022204..1022497 (+) 294 Protein_985 transposase -
  U0448_RS05215 tnpB 1022520..1022870 (-) 351 WP_000586658.1 IS66 family insertion sequence element accessory protein TnpB -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25241.10 Da        Isoelectric Point: 7.3688

>NTDB_id=911345 U0448_RS05185 WP_000649971.1 1017762..1018424(-) (comFC/cflB) [Streptococcus pneumoniae strain 21011]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=911345 U0448_RS05185 WP_000649971.1 1017762..1018424(-) (comFC/cflB) [Streptococcus pneumoniae strain 21011]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAAGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7MFB3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

100

100

1
  comFC/cflB Streptococcus pneumoniae Rx1

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae D39

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae R6

99.545

100

0.995
  comFC/cflB Streptococcus mitis NCTC 12261

91.818

100

0.918
  comFC/cflB Streptococcus mitis SK321

91.364

100

0.914