Detailed information    

insolico Bioinformatically predicted

Overview

Name   coiA   Type   Machinery gene
Locus tag   U0448_RS00675 Genome accession   NZ_CP139860
Coordinates   140949..141902 (-) Length   317 a.a.
NCBI ID   WP_000495909.1    Uniprot ID   A0A0H2UPP6
Organism   Streptococcus pneumoniae strain 21011     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 135949..146902
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0448_RS00650 - 136440..136535 (-) 96 Protein_129 IS630 family transposase -
  U0448_RS00655 - 136947..137288 (+) 342 Protein_130 transposase -
  U0448_RS00660 prsA 137405..138346 (-) 942 WP_000727935.1 peptidylprolyl isomerase PrsA -
  U0448_RS00665 - 138413..139126 (-) 714 WP_079114952.1 O-methyltransferase -
  U0448_RS00670 pepF 139128..140930 (-) 1803 WP_000244122.1 oligoendopeptidase F Regulator
  U0448_RS00675 coiA 140949..141902 (-) 954 WP_000495909.1 competence protein CoiA Machinery gene
  U0448_RS00680 tehB 141975..142835 (-) 861 WP_000413762.1 SAM-dependent methyltransferase TehB -
  U0448_RS00685 smpB 142851..143318 (-) 468 WP_001051750.1 SsrA-binding protein SmpB -
  U0448_RS00690 rnr 143281..145635 (-) 2355 WP_024475340.1 ribonuclease R -
  U0448_RS00695 secG 145737..145970 (-) 234 WP_000282517.1 preprotein translocase subunit SecG -
  U0448_RS00700 rpmG 146010..146159 (-) 150 WP_001809104.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 38243.86 Da        Isoelectric Point: 8.9865

>NTDB_id=911300 U0448_RS00675 WP_000495909.1 140949..141902(-) (coiA) [Streptococcus pneumoniae strain 21011]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide


Download         Length: 954 bp        

>NTDB_id=911300 U0448_RS00675 WP_000495909.1 140949..141902(-) (coiA) [Streptococcus pneumoniae strain 21011]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCTTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGCTATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTGTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

Competence protein CoiA-like family (CoiA_nuc)

(13-263)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UPP6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  coiA Streptococcus pneumoniae TIGR4

100

100

1
  coiA Streptococcus pneumoniae Rx1

99.369

100

0.994
  coiA Streptococcus pneumoniae D39

99.369

100

0.994
  coiA Streptococcus pneumoniae R6

99.369

100

0.994
  coiA Streptococcus mitis NCTC 12261

89.274

100

0.893
  coiA Lactococcus lactis subsp. cremoris KW2

42.593

100

0.435