Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   U0448_RS00670 Genome accession   NZ_CP139860
Coordinates   139128..140930 (-) Length   600 a.a.
NCBI ID   WP_000244122.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 21011     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 134128..145930
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0448_RS00635 - 134243..135085 (+) 843 WP_000954122.1 DUF368 domain-containing protein -
  U0448_RS00640 - 135085..135567 (+) 483 WP_001085888.1 aminoacyl-tRNA deacylase -
  U0448_RS00645 - 135567..136187 (+) 621 WP_000780813.1 histidine phosphatase family protein -
  U0448_RS00650 - 136440..136535 (-) 96 Protein_129 IS630 family transposase -
  U0448_RS00655 - 136947..137288 (+) 342 Protein_130 transposase -
  U0448_RS00660 prsA 137405..138346 (-) 942 WP_000727935.1 peptidylprolyl isomerase PrsA -
  U0448_RS00665 - 138413..139126 (-) 714 WP_079114952.1 O-methyltransferase -
  U0448_RS00670 pepF 139128..140930 (-) 1803 WP_000244122.1 oligoendopeptidase F Regulator
  U0448_RS00675 coiA 140949..141902 (-) 954 WP_000495909.1 competence protein CoiA Machinery gene
  U0448_RS00680 tehB 141975..142835 (-) 861 WP_000413762.1 SAM-dependent methyltransferase TehB -
  U0448_RS00685 smpB 142851..143318 (-) 468 WP_001051750.1 SsrA-binding protein SmpB -
  U0448_RS00690 rnr 143281..145635 (-) 2355 WP_024475340.1 ribonuclease R -

Sequence

Protein


Download         Length: 600 a.a.        Molecular weight: 69863.77 Da        Isoelectric Point: 4.5469

>NTDB_id=911299 U0448_RS00670 WP_000244122.1 139128..140930(-) (pepF) [Streptococcus pneumoniae strain 21011]
MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYEGHLLDSADNLLEITEFSLEMERQIEKLYVYAHMKND
QDTREAKYQEYYAKAMTLYSQLDQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQALYATYEQFQHTYAKTLQTNVKVQ
NYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRKHLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALK
KAEDALAVLGEDYLSRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSMHSSYTRET
QPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFRGTVFRQTQFAEFEHAIHQADQNGEVLTSDF
LNKLYADLNQEYYGLSKEDNPEIQYEWARIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPL
NVMRKAGVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA

Nucleotide


Download         Length: 1803 bp        

>NTDB_id=911299 U0448_RS00670 WP_000244122.1 139128..140930(-) (pepF) [Streptococcus pneumoniae strain 21011]
ATGGTATTACAAAGAAATGAAATAAATGAAAAAGATACATGGGATCTATCAACGATCTACCCAACTGACCAGGCTTGGGA
AGAAGCCTTAAAAGATTTAACAGAACAATTGGAGACAGTAGCCCAGTATGAAGGCCATCTCTTGGATAGTGCGGATAACC
TACTAGAAATCACTGAATTTTCTCTTGAAATGGAACGCCAGATAGAGAAGCTTTACGTTTATGCTCATATGAAGAATGAC
CAGGATACACGTGAAGCTAAGTATCAAGAGTACTATGCCAAGGCCATGACACTCTACAGCCAGTTAGACCAAGCCTTTTC
ATTCTATGAGCCTGAATTTATGGAGATTAGCGAAAAGCAGTATGCTGACTTTTTAGAAGCTCAACCAAAGCTGCAGGTTT
ATCAACACTATTTTGACAAGCTCTTGCAAGGCAAGGATCACGTTCTCTCACAACGTGAAGAAGAATTATTGGCTGGAGCT
GGAGAAATCTTTGGTTCAGCAAGTGAAACCTTCGCTATCTTGGACAATGCGGATATTGTGTTCCCTTATGTCCTAGACGA
TGATGGTAAAGAAGTTCAGCTATCTCATGGGACTTACACACGTTTGATGGAGTCTAAAAAACGTGAGGTTCGCCGTGGTG
CCTATCAAGCTCTTTATGCGACTTACGAACAATTCCAACACACCTATGCCAAAACCTTGCAAACCAATGTTAAGGTGCAA
AATTACCGTGCTAAAGTTCGTAACTACAAGAGTGCTCGTCATGCAGCCCTCGCAGCGAATTTTGTTCCAGAAAGTGTTTA
TGACAATTTGGTAGCAGCAGTTCGCAAGCATTTGCCACTCTTACATCGCTATCTTGAGCTTCGTTCAAAAATCTTGGGGA
TTTCAGATCTCAAGATGTACGATGTCTACACACCGCTTTCATCTGTTGAATACAGTTTTACCTACCAAGAAGCCTTGAAA
AAAGCAGAAGATGCTTTGGCAGTCTTGGGTGAGGATTACTTGAGCCGTGTCAAACGTGCCTTCAGCGAGCGTTGGATTGA
TGTTTACGAAAATCAAGGCAAGCGTTCAGGTGCCTACTCTGGTGGTTCTTATGATACCAATGCCTTTATGCTTCTCAACT
GGCAGGACAATCTGGACAATCTCTTTACTCTTGTTCATGAAACAGGTCACAGTATGCATTCAAGCTATACTCGTGAAACT
CAGCCTTATGTTTACGGAGATTACTCTATCTTTTTGGCTGAGATTGCCTCAACTACCAATGAAAATATCTTGACGGAGAA
ATTATTGGAAGAAGTGGAAGACGACGCAACACGCTTTGCTATTCTCAATAACTTCCTAGATGGTTTCCGTGGAACAGTTT
TCCGCCAAACTCAATTTGCTGAGTTTGAACACGCCATTCACCAAGCAGATCAAAATGGGGAGGTCTTGACAAGCGATTTC
CTAAATAAACTCTACGCAGACTTGAACCAAGAGTATTATGGTTTGAGTAAGGAAGACAATCCTGAAATCCAATACGAGTG
GGCTCGCATTCCACACTTCTACTATAACTACTATGTATATCAATATTCAACTGGCTTTGCGGCCGCCTCAGCCTTGGCTG
AAAAAATTGTCCATGGTAGTCAAGAAGACCGTGACCGCTATATCGACTACCTCAAGGCAGGTAAGTCGGACTATCCACTT
AATGTCATGAGAAAAGCTGGTGTTGATATGGAGAAGGAAGACTACCTCAACGATGCCTTTGCAGTCTTTGAACGCCGTTT
AAATGAGTTTGAAGCCCTTGTTGAAAAATTAGGATTGGCATAA

Domains

Predicted by InterproScan.

Peptidase family M3 (Peptidase_M3)

(202-581)

Oligopeptidase F (Peptidase_M3_N)

(112-181)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

67.45

99.333

0.67