Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   SM123_RS08290 Genome accession   NZ_CP139419
Coordinates   1710410..1712281 (-) Length   623 a.a.
NCBI ID   WP_320909415.1    Uniprot ID   -
Organism   Streptococcus lingualis strain S5     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1705410..1717281
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SM123_RS08265 (SM123_08265) - 1706144..1706509 (-) 366 WP_320909413.1 S1 RNA-binding domain-containing protein -
  SM123_RS08270 (SM123_08270) - 1706511..1707911 (-) 1401 WP_320909414.1 Cof-type HAD-IIB family hydrolase -
  SM123_RS08275 (SM123_08275) - 1707956..1708588 (-) 633 WP_003004009.1 response regulator transcription factor -
  SM123_RS08280 (SM123_08280) - 1708585..1709601 (-) 1017 WP_118096436.1 sensor histidine kinase -
  SM123_RS08285 (SM123_08285) liaF 1709598..1710293 (-) 696 WP_003003865.1 cell wall-active antibiotics response protein LiaF -
  SM123_RS08290 (SM123_08290) stkP 1710410..1712281 (-) 1872 WP_320909415.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  SM123_RS08295 (SM123_08295) - 1712278..1713018 (-) 741 WP_195487762.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  SM123_RS08300 (SM123_08300) rsmB 1713040..1714353 (-) 1314 WP_320909416.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  SM123_RS08305 (SM123_08305) fmt 1714343..1715278 (-) 936 WP_049483471.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 623 a.a.        Molecular weight: 68392.55 Da        Isoelectric Point: 5.8341

>NTDB_id=909551 SM123_RS08290 WP_320909415.1 1710410..1712281(-) (stkP) [Streptococcus lingualis strain S5]
MIQIGKIFAGRYKIIQQIGRGGMADVYLARDLILDGEEVAVKVLRTNYQTDPIAVARFQREAKAMAELDHPNIVRITDIG
EEEGQQYLAMEYVAGLDLKRYIKENAPLSNEEAVRLMGQILLAMRLAHTRGIIHRDLKPQNVLLTPDGTAKVSDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSIREENKNVP
QALENVVIKATAKKLTDGYKSVAEMYVDLSSCLSYERRNEKKLIFEDQSKADTKTLPKVSPTPKTAPVPISEVRSEISSV
DPNRPLSDQQTMAPSKKPRRRLRARYKVLFVAIALVLAAFTFLLYMSPANKTVPDVSGKTIAEARAVIEGQDLQVGEEKE
EYSDSVAEGYVIRTNPNAGAQKKEQSRIDLIVSKGPNSFEMPNYVGETRAKAEEDLKNTYKVSSKMITIEEVETFDYAAG
TVLEQTPAPGEQYSLNSKTKIVLKVAKETTSIEMPNYVGSTYDFARSNLIEIYGIKEANIELRKTEHLPDGVVVSAGQIV
SQTPEVSSTVDINRTRIVLTVYEPKVTASSSTKASSSSDASSSSSAERSDTESSSSSATGGDS

Nucleotide


Download         Length: 1872 bp        

>NTDB_id=909551 SM123_RS08290 WP_320909415.1 1710410..1712281(-) (stkP) [Streptococcus lingualis strain S5]
ATGATTCAAATCGGCAAAATTTTTGCCGGGCGATATAAAATCATCCAACAAATTGGACGCGGCGGGATGGCAGATGTTTA
TCTTGCGCGTGATTTAATTTTAGATGGGGAAGAAGTTGCAGTCAAGGTACTGCGTACGAATTACCAGACGGATCCCATTG
CGGTTGCGCGTTTTCAGCGTGAAGCAAAGGCGATGGCAGAGCTGGACCATCCAAATATCGTTCGGATTACAGACATTGGC
GAAGAAGAAGGACAACAATACCTTGCAATGGAATATGTTGCAGGTTTAGACTTGAAACGCTATATCAAAGAAAATGCTCC
TTTATCAAATGAAGAAGCTGTTCGTTTGATGGGGCAGATCCTTCTAGCTATGCGTCTTGCCCATACGCGTGGCATTATCC
ATAGAGATTTAAAACCACAGAATGTCCTCTTGACACCAGATGGAACAGCAAAAGTTTCAGACTTTGGGATTGCAGTGGCC
TTTGCAGAGACTAGCTTGACCCAGACCAACTCGATGTTGGGGTCGGTTCATTATTTGTCCCCTGAGCAGGCGCGTGGTTC
AAAAGCTACGGTGCAAAGTGACATCTACGCGATGGGAATCATTTTCTATGAGATGTTGACAGGACACATTCCTTATGATG
GAGATAGTGCAGTCACAATTGCTTTGCAGCATTTTCAAAAGCCACTCCCCTCTATTCGTGAAGAAAATAAGAATGTTCCA
CAAGCTTTAGAAAATGTGGTGATCAAAGCGACAGCTAAAAAACTGACGGATGGCTATAAATCAGTGGCAGAGATGTATGT
GGACCTTTCAAGTTGCTTGTCCTATGAGAGAAGAAATGAGAAAAAACTGATTTTTGAAGATCAATCGAAAGCTGATACAA
AGACTCTTCCAAAAGTGAGTCCAACTCCAAAGACGGCTCCTGTTCCAATCTCTGAGGTACGCAGTGAAATCAGTTCGGTA
GATCCTAATCGACCATTATCTGACCAGCAGACAATGGCACCAAGTAAAAAGCCAAGAAGACGCTTGCGGGCGCGCTACAA
GGTCTTGTTTGTTGCCATTGCACTAGTTCTTGCAGCCTTTACTTTTTTGTTGTATATGAGCCCAGCCAATAAAACAGTTC
CAGATGTTTCCGGCAAAACCATTGCCGAAGCTAGAGCGGTTATTGAGGGACAAGACCTTCAAGTCGGTGAAGAGAAAGAA
GAGTACAGTGATTCGGTTGCAGAAGGCTATGTGATTCGGACCAATCCAAATGCAGGTGCTCAAAAGAAAGAACAAAGTCG
CATTGATTTGATTGTTTCAAAAGGTCCAAATAGTTTTGAAATGCCAAACTATGTAGGAGAAACACGAGCTAAAGCAGAGG
AAGATCTGAAAAATACTTATAAAGTATCAAGCAAAATGATCACGATTGAAGAAGTTGAGACCTTCGATTATGCTGCAGGG
ACAGTTCTTGAACAAACCCCAGCTCCAGGAGAGCAATATTCTCTGAATTCAAAAACCAAGATTGTTTTGAAAGTAGCGAA
AGAAACGACTTCAATTGAAATGCCAAACTATGTTGGATCAACTTATGATTTTGCTAGAAGTAATTTGATTGAGATCTATG
GTATTAAAGAAGCCAATATCGAATTAAGAAAAACGGAACATCTCCCTGATGGGGTAGTTGTTTCTGCCGGTCAAATTGTC
AGTCAAACTCCAGAAGTTTCGAGTACGGTGGATATTAACCGAACACGAATTGTTTTGACTGTATATGAGCCTAAAGTGAC
GGCTTCTTCAAGTACGAAAGCCTCATCAAGTTCAGATGCATCTAGTTCATCCTCTGCTGAACGATCAGATACAGAAAGTT
CTAGCAGTAGTGCAACTGGTGGAGATTCATAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-237)

PASTA domain (PASTA)

(440-507)

PASTA domain (PASTA)

(512-582)

PASTA domain (PASTA)

(372-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

62.27

96.148

0.599
  stkP Streptococcus pneumoniae D39

62.104

96.148

0.597
  stkP Streptococcus pneumoniae R6

62.104

96.148

0.597
  stkP Streptococcus pneumoniae Rx1

61.937

96.148

0.596
  pknB Streptococcus mutans UA159

58.748

87.159

0.512
  stkP/pknB Streptococcus salivarius strain HSISS4

54.174

94.222

0.51