Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA/cilB/dalA   Type   Machinery gene
Locus tag   SM123_RS05570 Genome accession   NZ_CP139419
Coordinates   1183325..1184173 (+) Length   282 a.a.
NCBI ID   WP_118398370.1    Uniprot ID   A0AAE8DHC9
Organism   Streptococcus lingualis strain S5     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1178325..1189173
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SM123_RS05540 (SM123_05540) dapA 1178546..1179481 (+) 936 WP_049483556.1 4-hydroxy-tetrahydrodipicolinate synthase -
  SM123_RS10275 - 1179490..1179537 (-) 48 Protein_1073 hypothetical protein -
  SM123_RS05550 (SM123_05550) - 1180276..1180614 (+) 339 WP_003001449.1 ATP cone domain-containing protein -
  SM123_RS05555 (SM123_05555) ylqF 1180726..1181577 (+) 852 WP_254732486.1 ribosome biogenesis GTPase YlqF -
  SM123_RS05560 (SM123_05560) - 1181564..1182331 (+) 768 WP_320909171.1 ribonuclease HII -
  SM123_RS05565 (SM123_05565) - 1182335..1183264 (+) 930 WP_201089147.1 ROK family protein -
  SM123_RS05570 (SM123_05570) dprA/cilB/dalA 1183325..1184173 (+) 849 WP_118398370.1 DNA-processing protein DprA Machinery gene
  SM123_RS05575 (SM123_05575) topA 1184260..1186341 (+) 2082 WP_320909172.1 type I DNA topoisomerase -
  SM123_RS05580 (SM123_05580) trmFO 1186545..1187879 (+) 1335 WP_320909173.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -
  SM123_RS05585 (SM123_05585) - 1187973..1188800 (+) 828 WP_320909174.1 alpha/beta hydrolase -

Sequence

Protein


Download         Length: 282 a.a.        Molecular weight: 31750.53 Da        Isoelectric Point: 6.4997

>NTDB_id=909534 SM123_RS05570 WP_118398370.1 1183325..1184173(+) (dprA/cilB/dalA) [Streptococcus lingualis strain S5]
MEKFEIFKLKEAGLSNEQVLRVLDYCRKEQVLPSLEEIARIARCRSILHFVDKYRQLDEDHLHKEFERFPSLSIFDPEYP
EELLQIYNPPVLLFYQGDLQLLSKPKIAVVGARETTREGVRSVEKIIKELGNELVIVSGLAKGIDATAHYASIRNGGKTI
GVIGTGLDVFYPKSNQRLQSHMGEHHLILSEYGPGQAPLKFHFPERNRIIAGLCQAVIVAEARFRSGSLITCERAMEEGR
DVFAIPGNILDGKSAGCHHLIQEGAKLITSGQDILDELKYEL

Nucleotide


Download         Length: 849 bp        

>NTDB_id=909534 SM123_RS05570 WP_118398370.1 1183325..1184173(+) (dprA/cilB/dalA) [Streptococcus lingualis strain S5]
ATGGAGAAATTTGAAATCTTTAAATTAAAAGAAGCCGGTTTATCAAATGAGCAAGTCTTGAGAGTCTTGGACTACTGTAG
GAAAGAGCAAGTCTTACCAAGCTTAGAAGAGATAGCGAGGATCGCTCGCTGTCGCAGTATCCTTCATTTTGTAGACAAAT
ACCGGCAACTAGATGAAGACCATTTACACAAGGAGTTTGAACGGTTCCCATCTCTATCCATTTTTGATCCAGAATACCCT
GAGGAATTGCTACAGATCTACAATCCTCCTGTACTCCTTTTTTACCAAGGGGATTTGCAACTGTTAAGCAAACCGAAGAT
TGCAGTTGTTGGAGCTCGAGAGACCACGCGAGAAGGGGTTCGTTCTGTAGAGAAGATAATTAAGGAACTTGGAAATGAAC
TGGTCATTGTTAGTGGACTTGCTAAGGGAATTGATGCGACAGCTCATTATGCCAGTATACGAAATGGTGGTAAGACCATC
GGAGTGATTGGAACGGGACTGGATGTCTTTTATCCTAAAAGCAATCAGAGATTACAGTCCCATATGGGGGAACACCATCT
GATCTTGAGCGAGTATGGTCCAGGGCAGGCACCACTTAAGTTTCATTTTCCTGAGAGAAATCGCATCATTGCTGGTCTCT
GTCAGGCAGTGATTGTGGCAGAGGCGCGATTCCGTTCAGGCAGTTTGATTACTTGTGAGCGTGCTATGGAAGAAGGCCGA
GACGTTTTCGCTATTCCAGGAAATATTTTAGATGGAAAATCTGCAGGCTGCCATCACCTAATTCAAGAAGGCGCAAAGCT
TATCACATCAGGCCAGGACATTCTTGATGAATTGAAATACGAATTGTGA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(72-269)

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(1-62)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

65

99.291

0.645
  dprA/cilB/dalA Streptococcus pneumoniae D39

64.643

99.291

0.642
  dprA/cilB/dalA Streptococcus pneumoniae R6

64.643

99.291

0.642
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

64.643

99.291

0.642
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

64.643

99.291

0.642
  dprA/cilB/dalA Streptococcus mitis SK321

64.286

99.291

0.638
  dprA Streptococcus mutans UA159

62.143

99.291

0.617
  dprA Lactococcus lactis subsp. cremoris KW2

52.313

99.645

0.521
  dprA Bacillus subtilis subsp. subtilis str. 168

41.608

100

0.422