Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   SM121_RS08425 Genome accession   NZ_CP139418
Coordinates   1726378..1728624 (-) Length   748 a.a.
NCBI ID   WP_320910849.1    Uniprot ID   -
Organism   Streptococcus dentalis strain S1     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1721378..1733624
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SM121_RS08405 (SM121_08405) - 1722265..1723737 (-) 1473 WP_320910846.1 helicase HerA-like domain-containing protein -
  SM121_RS08410 (SM121_08410) sodA 1723948..1724553 (-) 606 WP_003006336.1 superoxide dismutase SodA -
  SM121_RS08415 (SM121_08415) holA 1724642..1725676 (-) 1035 WP_320910847.1 DNA polymerase III subunit delta -
  SM121_RS08420 (SM121_08420) - 1725700..1726302 (-) 603 WP_320910848.1 DUF805 domain-containing protein -
  SM121_RS08425 (SM121_08425) comEC/celB 1726378..1728624 (-) 2247 WP_320910849.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  SM121_RS08430 (SM121_08430) comEA/celA/cilE 1728605..1729273 (-) 669 WP_320910850.1 helix-hairpin-helix domain-containing protein Machinery gene
  SM121_RS08435 (SM121_08435) - 1729340..1730086 (-) 747 WP_320910851.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  SM121_RS08440 (SM121_08440) - 1730262..1732601 (+) 2340 WP_320910852.1 cation-translocating P-type ATPase -
  SM121_RS08445 (SM121_08445) - 1732682..1733428 (+) 747 WP_049514084.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -

Sequence

Protein


Download         Length: 748 a.a.        Molecular weight: 85676.18 Da        Isoelectric Point: 9.2147

>NTDB_id=909501 SM121_RS08425 WP_320910849.1 1726378..1728624(-) (comEC/celB) [Streptococcus dentalis strain S1]
MLSRWIKNLPFSLVHLAFVLLWLYFSVYQPSWLSISGLVVVGILAVHHYKGERSSLLGLALAILCFAAFFVFQRIQDHPV
QVESQPPAHLHLIPDTIKINGDALSFRAKNQGRTYQVFYTLKSEKEKQHWQSQTHLLELTYKGAIEEPEGQRNFRGFDYR
SYLETQGIHYQIKIETIQSALPIQTWNVFDCLSQWRRQAIVWSKKHFPQPMNQYMTGLLFGYLDTDFEEMDQLYTSLGII
HLFALSGMQVGFFINGIRKALLRLGILQETVDIWMVPISLVYAGLTGFSVSVVRSLLQKILSQKGVRGMENMAMTLMILM
LLMPKFFLTAGGVLSCAYAFILTLVDTSSYSGLKKILVESFWISLGILPLLTYYFSVFQPWSLPLTFLFSFLFDLVLLPG
LTVLFILSILKPLTIFNSFFLLIEECIRWISKLTSLPLVFGQPTGLALIALFLLLGILYDLRKQKKRRFLLIGMILLIFC
WTKHPLENEITMVDIGQGDSIFLRDWKGRTILIDVGGRVTFKSGDKWQERSQSANADQTLIPYLKSRGVGKIDALVLTHT
DQDHMGDMVEVAKQIPVKKVYVSPGSLTNSQFREKLKQLHSPIKVVQRGDRLPIFDHHLEVLSPDEVGDGKNDDSIVLYG
QFYQKRFLFTGDLEEAGEKKLLENDPQLQVDVLKVGHHGSKGSSSDVFLDQLHPQLALISVGKKNRYQHPHKELLDRLEE
RSISYLRTDERGAIRLIGWDHWRVETVR

Nucleotide


Download         Length: 2247 bp        

>NTDB_id=909501 SM121_RS08425 WP_320910849.1 1726378..1728624(-) (comEC/celB) [Streptococcus dentalis strain S1]
ATGCTTTCACGGTGGATTAAAAACCTTCCTTTTTCGCTTGTCCATCTCGCCTTTGTACTCCTATGGTTGTATTTTAGTGT
TTATCAACCATCTTGGCTTTCGATCAGCGGTCTAGTAGTAGTGGGAATTTTAGCGGTTCATCACTATAAAGGGGAGCGCT
CAAGTTTGCTAGGGCTTGCTTTAGCAATCCTTTGTTTTGCGGCCTTCTTTGTCTTTCAGCGAATACAAGATCATCCAGTA
CAAGTAGAAAGTCAGCCCCCAGCCCATTTACATCTGATCCCAGATACCATCAAGATCAATGGGGACGCCTTGTCTTTTCG
TGCTAAAAATCAGGGAAGGACCTACCAAGTCTTCTACACTTTAAAATCAGAAAAAGAAAAACAGCATTGGCAAAGTCAAA
CTCATTTGTTGGAGTTGACGTATAAAGGTGCTATAGAAGAGCCAGAAGGGCAGCGAAATTTTAGAGGATTTGACTACCGG
TCTTATTTGGAAACACAGGGCATTCACTATCAAATAAAAATTGAAACGATCCAATCTGCTCTCCCTATCCAAACTTGGAA
TGTTTTCGATTGCCTATCTCAATGGAGGCGCCAAGCCATTGTTTGGAGCAAGAAGCACTTTCCGCAACCGATGAACCAGT
ATATGACCGGCCTTCTTTTTGGCTATTTAGATACGGATTTTGAAGAGATGGACCAGCTTTACACGAGTTTAGGAATCATC
CATTTATTCGCCTTATCTGGGATGCAGGTTGGCTTTTTCATCAATGGGATCCGGAAAGCTCTCTTACGTTTAGGAATCTT
GCAAGAGACAGTCGATATCTGGATGGTTCCAATTTCTTTGGTCTATGCTGGCTTGACAGGTTTTTCTGTTTCAGTGGTTC
GCAGCCTCTTGCAGAAGATCCTCTCTCAAAAGGGGGTCCGAGGGATGGAGAATATGGCGATGACCTTGATGATCTTAATG
TTGCTCATGCCCAAGTTTTTCCTGACAGCTGGAGGGGTCTTGAGTTGTGCCTATGCCTTTATTTTGACCTTGGTAGATAC
CAGCTCTTATTCAGGACTTAAAAAGATACTAGTGGAAAGTTTCTGGATTAGCCTGGGGATTTTGCCCCTTTTGACCTATT
ACTTTAGCGTCTTTCAACCCTGGTCACTCCCTTTAACCTTCCTCTTTTCTTTCTTATTTGACCTTGTCCTTCTTCCAGGT
TTAACGGTGCTATTTATCTTATCGATTCTAAAGCCCCTTACCATTTTTAACAGTTTCTTTCTTCTCATAGAGGAGTGTAT
TCGTTGGATTTCAAAGCTCACGTCGCTACCTTTGGTATTTGGTCAGCCAACGGGACTAGCTCTGATCGCTCTCTTCCTTC
TTTTAGGGATCTTGTATGATCTTCGAAAGCAAAAAAAACGTCGTTTCCTGTTAATAGGCATGATTCTACTCATCTTTTGT
TGGACCAAGCATCCTTTAGAAAATGAGATCACCATGGTGGATATCGGTCAAGGAGATAGTATCTTTTTACGTGATTGGAA
AGGAAGAACCATATTAATTGATGTCGGAGGACGCGTCACTTTTAAAAGTGGAGACAAGTGGCAAGAGCGCAGTCAATCTG
CTAATGCGGATCAAACCTTGATTCCATATCTCAAGAGTCGAGGTGTTGGAAAAATCGATGCGCTGGTCTTGACTCATACA
GACCAGGACCATATGGGTGATATGGTGGAGGTCGCCAAACAAATCCCAGTTAAAAAAGTGTATGTCAGTCCAGGCAGTCT
AACCAATTCTCAATTTCGAGAGAAATTGAAACAGCTTCATAGTCCGATTAAAGTAGTCCAGAGAGGGGATCGACTTCCTA
TTTTTGATCATCATCTAGAAGTCTTATCCCCTGATGAAGTGGGGGATGGTAAAAATGATGATTCGATTGTCCTCTATGGG
CAGTTCTATCAGAAACGATTTTTGTTCACGGGTGATCTAGAAGAAGCTGGAGAGAAAAAACTATTGGAAAACGATCCACA
ATTACAAGTAGATGTCTTGAAAGTAGGCCACCACGGATCTAAAGGTTCCTCTAGTGATGTGTTTTTAGACCAGTTACATC
CTCAGTTGGCCTTGATCTCTGTTGGAAAGAAAAATCGCTACCAGCATCCCCATAAAGAATTGCTCGATCGTCTAGAGGAA
CGCTCTATTTCTTATCTTCGTACCGATGAAAGAGGAGCAATTCGCTTGATTGGATGGGACCATTGGAGGGTAGAAACGGT
CCGCTAG

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(496-700)

Domain of unknown function (DUF4131) (DUF4131)

(30-178)

Competence protein (Competence)

(218-463)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis SK321

53.405

100

0.535
  comEC/celB Streptococcus pneumoniae TIGR4

52.87

100

0.529
  comEC/celB Streptococcus mitis NCTC 12261

52.807

100

0.528
  comEC/celB Streptococcus pneumoniae Rx1

52.47

100

0.525
  comEC/celB Streptococcus pneumoniae D39

52.47

100

0.525
  comEC/celB Streptococcus pneumoniae R6

52.47

100

0.525
  comEC Lactococcus lactis subsp. cremoris KW2

47.53

100

0.476