Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   SM121_RS00085 Genome accession   NZ_CP139418
Coordinates   19634..20371 (-) Length   245 a.a.
NCBI ID   WP_155127058.1    Uniprot ID   A0A6A8V8X9
Organism   Streptococcus dentalis strain S1     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 14634..25371
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SM121_RS00065 (SM121_00065) - 15010..16236 (-) 1227 WP_320910917.1 cysteine desulfurase -
  SM121_RS00070 (SM121_00070) sufD 16246..17508 (-) 1263 WP_155127067.1 Fe-S cluster assembly protein SufD -
  SM121_RS00075 (SM121_00075) sufC 17575..18345 (-) 771 WP_155127064.1 Fe-S cluster assembly ATPase SufC -
  SM121_RS00080 (SM121_00080) - 18480..19637 (-) 1158 WP_320910918.1 MraY family glycosyltransferase -
  SM121_RS00085 (SM121_00085) mecA 19634..20371 (-) 738 WP_155127058.1 adaptor protein MecA Regulator
  SM121_RS00090 (SM121_00090) - 20507..21343 (-) 837 WP_155127055.1 undecaprenyl-diphosphate phosphatase -
  SM121_RS00095 (SM121_00095) - 21452..23359 (-) 1908 WP_155127052.1 DUF2207 domain-containing protein -
  SM121_RS00100 (SM121_00100) - 23477..25039 (+) 1563 WP_155127049.1 ABC transporter substrate-binding protein/permease -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28276.93 Da        Isoelectric Point: 4.0867

>NTDB_id=909460 SM121_RS00085 WP_155127058.1 19634..20371(-) (mecA) [Streptococcus dentalis strain S1]
MKMKQISDSTIKITIQLEDLEERGMEIADFLVPQEKTEEFFYAILDELEMPESFLDSGMLSFRVTPKPDKLDVFVTKSKI
DQQLDFEDLSDLPDMEELSRMTPDEFIKTLEKTISDKTKGDAEAIHHLEQEELRDNQEQDPTPEAPVSQYIYYILRFSNI
QQAVVFSKTVSFPVDTSELYKMGSDYYLTVLIDTEDQPNQYPTWLLAIIREYADDSEVTRAVLQEHGHLLMVSGAIENLK
KVASL

Nucleotide


Download         Length: 738 bp        

>NTDB_id=909460 SM121_RS00085 WP_155127058.1 19634..20371(-) (mecA) [Streptococcus dentalis strain S1]
ATGAAGATGAAGCAAATTAGTGATTCAACTATTAAGATCACAATCCAACTAGAAGACTTAGAAGAACGTGGGATGGAAAT
TGCTGATTTTCTTGTCCCGCAAGAAAAAACAGAAGAATTTTTCTACGCCATTTTGGATGAGCTCGAAATGCCAGAAAGCT
TCCTGGATAGCGGGATGCTGAGTTTTCGTGTGACACCAAAACCAGATAAATTGGATGTTTTTGTTACCAAATCAAAAATT
GACCAACAATTGGATTTTGAGGATTTGTCAGATCTTCCTGATATGGAAGAGTTGTCGCGCATGACGCCAGATGAATTTAT
CAAAACCTTGGAAAAAACAATCTCTGATAAGACAAAAGGGGATGCAGAAGCTATTCACCATTTGGAACAAGAAGAGTTAC
GTGACAATCAAGAACAAGATCCGACACCTGAAGCGCCAGTAAGTCAGTATATTTATTACATTTTGCGTTTTTCAAATATC
CAGCAAGCAGTTGTCTTTTCAAAAACGGTAAGCTTTCCAGTGGATACCTCTGAATTATACAAAATGGGATCCGATTATTA
TTTAACTGTCTTGATCGATACAGAGGATCAACCAAATCAATATCCAACCTGGTTACTTGCCATCATTCGGGAGTATGCGG
ATGATTCAGAAGTGACACGGGCAGTTTTGCAGGAACATGGTCATTTATTAATGGTGTCTGGTGCGATTGAGAATTTGAAG
AAAGTTGCTAGCTTATGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6A8V8X9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

68.163

100

0.682
  mecA Streptococcus pneumoniae D39

68.163

100

0.682
  mecA Streptococcus pneumoniae R6

68.163

100

0.682
  mecA Streptococcus pneumoniae TIGR4

68.163

100

0.682
  mecA Streptococcus mutans UA159

49.798

100

0.502
  mecA Streptococcus thermophilus LMD-9

47.755

100

0.478
  mecA Streptococcus thermophilus LMG 18311

47.347

100

0.473