Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   SON02_RS08325 Genome accession   NZ_CP139211
Coordinates   1897687..1899660 (+) Length   657 a.a.
NCBI ID   WP_135029349.1    Uniprot ID   A0A4Y9JHD0
Organism   Streptococcus sp. LysM4     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1892687..1904660
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SON02_RS08310 (SON02_08285) fmt 1894696..1895631 (+) 936 WP_135029362.1 methionyl-tRNA formyltransferase -
  SON02_RS08315 (SON02_08290) rsmB 1895621..1896931 (+) 1311 WP_135029360.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  SON02_RS08320 (SON02_08295) - 1896950..1897690 (+) 741 WP_135029351.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  SON02_RS08325 (SON02_08300) stkP 1897687..1899660 (+) 1974 WP_135029349.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  SON02_RS08330 - 1899722..1899937 (+) 216 Protein_1604 VanZ family protein -
  SON02_RS08335 (SON02_08315) liaF 1900928..1901623 (+) 696 WP_135029347.1 cell wall-active antibiotics response protein LiaF -
  SON02_RS08340 (SON02_08320) - 1901623..1902618 (+) 996 WP_135029398.1 sensor histidine kinase -
  SON02_RS08345 (SON02_08325) - 1902611..1903255 (+) 645 WP_135029345.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 657 a.a.        Molecular weight: 70812.72 Da        Isoelectric Point: 8.2050

>NTDB_id=908074 SON02_RS08325 WP_135029349.1 1897687..1899660(+) (stkP) [Streptococcus sp. LysM4]
MIQIGKIFADRYRIVRQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDQIAVQRFQREARAMADLDHPNIVRISDIG
EEDGQQYLAMEYVNGLDLKRYIKENAPLSNDEAVRIMGQILLAMRMAHTRGIVHRDLKPQNVLLTKDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIILFEMLTGRIPYDGDSAVTIALQHFQKALPSVREENPSVP
QALENVVLKATAKKLTDRYKTVAEMYTDIASSLSNNRLNEKKIVLENGKVDTKTLPKLSTIATEQRPPATKLPKVSTPTQ
HPDRPIAPPSKNKRKMRTRYKVLFGAILLIIAAVTTLLLNTPATIKVPDVSGQTLDVAREMLETAGLKVGKVREEPSSEV
EEGKVIRTNPAAGTSKREGRTVDIVVATTDAVMVPDVVGKDFDEARIELEAAGFVVKDTQEHSDSVEVNKVISTDPKANS
SKTKGSTITVTVSRGAERNQVPNVTGKSLETAMQELKAAGLVVGTTTEEYDTHQKGLIIRTEPGSGELLAKGSAVNLVVS
KGPAPVMPDFGILKTSYADARRQLQNLGINVTVEKIEDSSYPVGGDLVVGQYPAAGTAIGESVTLYVSVAVPASSTASSS
LDGGSSGSSSTTRSSGN

Nucleotide


Download         Length: 1974 bp        

>NTDB_id=908074 SON02_RS08325 WP_135029349.1 1897687..1899660(+) (stkP) [Streptococcus sp. LysM4]
ATGATTCAGATTGGAAAAATCTTTGCTGATCGCTACCGGATTGTTCGTCAAATTGGACGTGGTGGAATGGCGGATGTTTA
TCTAGCAAAAGATTTGATTTTGGACGGTGAAGAAGTTGCTGTCAAGGTCCTTCGAACCAACTATCAAACAGATCAGATAG
CTGTGCAACGTTTTCAGCGAGAAGCTAGAGCCATGGCAGATTTGGATCATCCGAATATTGTGCGTATTTCAGATATTGGT
GAAGAAGACGGGCAACAATATTTGGCGATGGAATATGTCAATGGTCTTGATTTAAAACGCTATATCAAAGAGAATGCGCC
CCTCTCAAATGATGAAGCGGTGCGGATTATGGGACAAATCCTGCTAGCGATGAGAATGGCTCATACCCGTGGTATTGTCC
ACCGTGATTTGAAACCGCAGAATGTCTTATTGACCAAAGACGGGACAGCCAAGGTAACAGATTTTGGGATTGCAGTAGCC
TTTGCAGAAACCAGCTTAACTCAGACCAATTCGATGTTAGGCTCGGTTCATTATTTATCACCTGAACAGGCTCGTGGATC
AAAAGCTACGGTTCAAAGTGATATTTATGCGATGGGAATTATCCTATTTGAAATGTTGACAGGACGGATTCCCTATGACG
GAGATAGTGCTGTAACGATTGCGCTTCAGCATTTTCAGAAAGCCTTACCTTCTGTAAGGGAAGAAAATCCTAGCGTGCCA
CAGGCGCTTGAAAATGTTGTTTTAAAAGCAACAGCAAAAAAACTCACAGACCGCTATAAGACAGTTGCCGAGATGTATAC
GGATATTGCCTCTTCGCTGTCAAATAATCGTCTGAACGAAAAGAAGATTGTCTTAGAAAATGGAAAAGTAGACACTAAGA
CCCTACCAAAACTATCGACCATTGCAACAGAGCAGAGACCGCCTGCGACTAAACTTCCGAAAGTGTCAACCCCTACCCAA
CATCCAGATCGTCCGATAGCCCCTCCGTCAAAGAACAAGCGAAAAATGAGGACGCGTTACAAGGTATTGTTTGGGGCAAT
TTTATTGATTATTGCTGCTGTTACTACTCTTTTACTGAATACTCCTGCGACCATTAAGGTTCCAGATGTCAGTGGTCAGA
CCTTAGATGTTGCTCGGGAAATGCTAGAAACCGCAGGTTTAAAGGTCGGAAAAGTAAGGGAAGAGCCGTCTTCGGAGGTT
GAAGAAGGAAAGGTCATTCGTACAAATCCAGCAGCCGGTACCTCTAAGCGTGAGGGACGTACGGTTGATATCGTTGTGGC
GACCACGGATGCAGTGATGGTACCGGATGTAGTGGGAAAGGACTTTGACGAGGCTAGGATTGAACTAGAAGCAGCAGGTT
TTGTCGTCAAAGATACGCAGGAACACAGCGATAGCGTGGAGGTAAATAAGGTCATCTCGACAGACCCGAAAGCCAATTCT
TCTAAGACCAAGGGGAGTACGATTACAGTGACGGTGTCTAGAGGAGCTGAACGAAATCAGGTTCCCAATGTCACAGGTAA
GAGCCTAGAGACAGCCATGCAAGAATTAAAAGCAGCAGGTTTGGTAGTTGGAACAACAACTGAAGAATACGATACACATC
AAAAAGGGTTGATTATTCGTACAGAACCAGGTTCTGGAGAGTTACTTGCGAAAGGTTCAGCTGTGAATCTTGTCGTCTCA
AAAGGTCCAGCGCCAGTTATGCCAGATTTTGGCATCTTAAAAACAAGTTATGCAGATGCTCGTAGGCAGTTACAAAATTT
AGGAATCAATGTAACGGTTGAAAAAATTGAGGACTCTAGCTATCCTGTCGGTGGAGATTTAGTAGTGGGACAATATCCTG
CTGCTGGTACCGCTATTGGAGAAAGTGTTACTCTCTATGTATCTGTAGCAGTTCCTGCGTCGTCAACGGCAAGTAGTAGC
CTTGATGGAGGGAGTTCTGGCAGTAGCTCTACTACTAGAAGCTCAGGTAATTAG

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(575-628)

PASTA domain (PASTA)

(432-493)

PASTA domain (PASTA)

(500-561)

PASTA domain (PASTA)

(365-427)

Protein kinase domain (Pkinase)

(12-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4Y9JHD0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

54.354

100

0.551
  stkP Streptococcus pneumoniae D39

54.054

100

0.548
  stkP Streptococcus pneumoniae R6

54.054

100

0.548
  stkP Streptococcus pneumoniae Rx1

53.904

100

0.546
  stkP/pknB Streptococcus salivarius strain HSISS4

53.671

87.062

0.467
  pknB Streptococcus mutans UA159

57.25

80.822

0.463