Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   SOL79_RS01370 Genome accession   NZ_CP139210
Coordinates   304886..305560 (-) Length   224 a.a.
NCBI ID   WP_135026742.1    Uniprot ID   A0A4Y9JNA5
Organism   Streptococcus sp. VEG1o     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 299886..310560
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SOL79_RS01350 (SOL79_01345) - 301410..301613 (+) 204 WP_167752584.1 hypothetical protein -
  SOL79_RS01355 (SOL79_01350) - 301681..301968 (+) 288 WP_167752583.1 transposase -
  SOL79_RS01360 (SOL79_01355) - 302174..303394 (-) 1221 WP_135026744.1 transglutaminase domain-containing protein -
  SOL79_RS01365 (SOL79_01360) ciaH 303514..304896 (-) 1383 WP_135026743.1 sensor histidine kinase Regulator
  SOL79_RS01370 (SOL79_01365) ciaR 304886..305560 (-) 675 WP_135026742.1 response regulator transcription factor Regulator
  SOL79_RS01375 (SOL79_01370) phoU 306287..306943 (-) 657 WP_135026741.1 phosphate signaling complex protein PhoU -
  SOL79_RS01380 (SOL79_01375) pstB 306962..307720 (-) 759 WP_135026740.1 phosphate ABC transporter ATP-binding protein PstB -
  SOL79_RS01385 (SOL79_01380) pstB 307733..308536 (-) 804 WP_135026739.1 phosphate ABC transporter ATP-binding protein PstB -
  SOL79_RS01390 (SOL79_01385) pstA 308547..309440 (-) 894 WP_135026738.1 phosphate ABC transporter permease PstA -
  SOL79_RS01395 (SOL79_01390) pstC 309430..310347 (-) 918 WP_135026737.1 phosphate ABC transporter permease subunit PstC -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25461.12 Da        Isoelectric Point: 4.2184

>NTDB_id=907990 SOL79_RS01370 WP_135026742.1 304886..305560(-) (ciaR) [Streptococcus sp. VEG1o]
MIKILLVEDDLSLSNSVFDFLDDFADVMQFFDGDEGLYEAESGVYDLILLDLMLPEKDGFQVLKELREKGITTPVLITTA
KESLDDKGHGFELGADDYLTKPFYLEELRMRIQALLKRSGKFNENVLVFGELSVDLSTNTSTVDGDEVELLGKEFDLLVY
FLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTTFAKQLQTLRSVGYILKNVD

Nucleotide


Download         Length: 675 bp        

>NTDB_id=907990 SOL79_RS01370 WP_135026742.1 304886..305560(-) (ciaR) [Streptococcus sp. VEG1o]
ATGATTAAGATATTATTAGTAGAAGACGATTTGAGTTTGTCAAATTCAGTATTTGACTTTTTAGATGATTTCGCAGATGT
CATGCAGTTTTTTGATGGTGATGAGGGATTATATGAAGCTGAATCTGGTGTCTATGACCTTATTTTGTTAGACTTGATGT
TGCCAGAAAAAGATGGTTTTCAAGTTCTTAAGGAATTGCGAGAAAAAGGTATCACAACCCCTGTTTTGATTACAACGGCC
AAGGAAAGTTTGGACGATAAAGGACATGGCTTTGAGCTGGGAGCGGATGACTACCTAACCAAGCCTTTTTACCTAGAAGA
ATTGCGGATGCGCATTCAAGCTCTTCTCAAGCGCTCGGGTAAGTTCAATGAAAACGTCTTAGTCTTTGGTGAGTTATCTG
TCGATCTTTCAACGAATACAAGCACTGTTGATGGTGATGAGGTAGAATTACTAGGAAAAGAATTTGACCTGCTTGTCTAT
TTCTTACAAAATCAAAATGTCATTCTACCTAAGACACAAATTTTTGATAGGATTTGGGGTTTTGATAGTGATACAACTAT
TTCAGTTGTGGAGGTTTATGTTTCTAAAATTAGAAAAAAATTGAAAGGGACGACCTTTGCTAAGCAGCTGCAAACCCTTA
GAAGTGTCGGATATATCTTGAAAAATGTTGATTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4Y9JNA5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

88.839

100

0.888
  ciaR Streptococcus pneumoniae Rx1

88.789

99.554

0.884
  ciaR Streptococcus pneumoniae D39

88.789

99.554

0.884
  ciaR Streptococcus pneumoniae TIGR4

88.789

99.554

0.884
  ciaR Streptococcus pneumoniae R6

88.789

99.554

0.884
  vicR Streptococcus mutans UA159

36.017

100

0.379
  covR Lactococcus lactis subsp. lactis strain DGCC12653

37.054

100

0.371