Detailed information NTG0902906

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: SGX79_RS13720
• Genome accession: NZ_CP138455
• Coordinates: 2721757..2722644 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain SATU135
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2716757..2727644

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SGX79_RS13690 (SGX79_13715)	-	2716775..2716863 (+)	89	Protein_2659	hypothetical protein	-
SGX79_RS13695 (SGX79_13720)	-	2716971..2717468 (-)	498	WP_001065267.1	glutathione peroxidase	-
SGX79_RS13700 (SGX79_13725)	-	2717478..2717738 (-)	261	WP_072434822.1	hypothetical protein	-
SGX79_RS13705 (SGX79_13730)	-	2718120..2718233 (-)	114	WP_072384844.1	hypothetical protein	-
SGX79_RS13710 (SGX79_13735)	-	2718897..2720897 (-)	2001	WP_000776746.1	ABC transporter permease	-
SGX79_RS13715 (SGX79_13740)	-	2720894..2721649 (-)	756	WP_001670202.1	ABC transporter ATP-binding protein	-
SGX79_RS13720 (SGX79_13745)	braS	2721757..2722644 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
SGX79_RS13725 (SGX79_13750)	braR	2722655..2723320 (-)	666	WP_000697883.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
SGX79_RS13730 (SGX79_13755)	-	2723346..2723546 (-)	201	WP_000604723.1	hypothetical protein	-
SGX79_RS13735 (SGX79_13760)	-	2723744..2725168 (+)	1425	WP_000953731.1	alkaline phosphatase	-
SGX79_RS13740 (SGX79_14525)	-	2725228..2725329 (-)	102	WP_000731972.1	SE2200 family small protein	-
SGX79_RS13745 (SGX79_13770)	-	2725451..2725906 (-)	456	WP_000106184.1	MarR family transcriptional regulator	-
SGX79_RS13750 (SGX79_13775)	-	2726152..2726913 (-)	762	WP_000323451.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=902906 SGX79_RS13720 WP_000143420.1 2721757..2722644(-) (braS) [Staphylococcus aureus strain SATU135]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=902906 SGX79_RS13720 WP_000143420.1 2721757..2722644(-) (braS) [Staphylococcus aureus strain SATU135]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATATGTAAAAGATAATGGTATCGGTATTAGTGAGGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993