Detailed information NTG0902286

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: SE858_RS04085
• Genome accession: NZ_CP138368
• Coordinates: 839921..841150 (+)
• Length: 409 a.a.
• NCBI ID: WP_000728358.1
• Uniprot ID: A0AAW3HT93
• Organism: Streptococcus agalactiae strain SagR92
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 834921..846150

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SE858_RS04060 (SE858_04060)	-	836082..838661 (+)	2580	WP_000154437.1	YfhO family protein	-
SE858_RS04080 (SE858_04080)	rlmH	839241..839720 (-)	480	WP_000768335.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
SE858_RS04085 (SE858_04085)	htrA	839921..841150 (+)	1230	WP_000728358.1	S1C family serine protease	Regulator
SE858_RS04090 (SE858_04090)	spo0J	841248..842021 (+)	774	WP_000456087.1	ParB/RepB/Spo0J family partition protein	Regulator
SE858_RS04095 (SE858_04095)	dnaA	842220..843581 (+)	1362	WP_000138202.1	chromosomal replication initiator protein DnaA	-
SE858_RS04100 (SE858_04100)	dnaN	843736..844872 (+)	1137	WP_000581132.1	DNA polymerase III subunit beta	-
SE858_RS04105 (SE858_04105)	-	844930..845823 (+)	894	WP_000987446.1	diacylglycerol kinase family protein	-
SE858_RS04110 (SE858_04110)	-	845833..846030 (+)	198	WP_000285199.1	DUF951 domain-containing protein	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 43118.59 Da
• Isoelectric Point: 9.5271

>NTDB_id=902286 SE858_RS04085 WP_000728358.1 839921..841150(+) (htrA) [Streptococcus agalactiae strain SagR92]
MKKKLVSSLLKCSLIIIVSFAGGAFASFVMNHNDNIPNGGVTKTSKVNYNNITPTTKAVKKVQNSVVSVINYKQQESRSD
LSDFYSHFFGNQGGNTDKGLQVYGEGSGVIYKKDGKNAYVVTNNHVIDGAKQIEIQLADGSKAVGKLVGSDTYSDLAVVK
IPSDKVSNIAEFADSSKLNIGETAIAIGSPLGTEYANSVTQGIVSSLKRTVTMTNEEGQTVSTNAIQTDAAINPGNSGGA
LINIEGQVIGINSSKISSTSNQTSGQSSGNSVEGMGFAIPSNDVVKIINQLESNGQVERPALGISMAGLSNLPSDVISKL
KIPSNVTNGIVVASIQSGMPAQGKLKKYDVITKVDDKEVVSPSDLQSLLYGHQVGDSITVTFYRGENKQTVTIKLTKTSK
DLAKQRANN

Nucleotide

• Length: 1230 bp

>NTDB_id=902286 SE858_RS04085 WP_000728358.1 839921..841150(+) (htrA) [Streptococcus agalactiae strain SagR92]
GTGAAAAAAAAATTAGTCTCATCACTTCTAAAGTGTTCTCTAATCATTATTGTTAGCTTTGCTGGTGGAGCATTTGCTAG
TTTTGTCATGAATCATAATGACAATATTCCAAATGGTGGTGTCACTAAAACTAGTAAAGTAAATTATAATAACATAACGC
CTACAACAAAAGCTGTTAAAAAGGTACAAAATAGTGTTGTTTCTGTTATCAATTATAAACAACAAGAGAGTCGTTCTGAC
CTATCAGACTTCTATAGTCATTTTTTTGGTAATCAGGGGGGCAACACTGATAAGGGCTTACAAGTTTACGGTGAAGGCTC
TGGAGTCATCTATAAAAAAGATGGTAAAAATGCCTATGTTGTCACTAATAACCACGTCATTGATGGGGCTAAACAAATTG
AAATTCAACTAGCTGATGGCTCAAAAGCAGTTGGGAAACTTGTTGGGTCAGATACCTACTCTGATTTAGCCGTCGTCAAA
ATTCCATCAGATAAGGTTTCAAATATTGCAGAATTTGCTGATTCATCAAAACTCAACATTGGTGAAACTGCTATAGCGAT
CGGAAGCCCTCTTGGAACTGAGTATGCAAATTCTGTAACTCAAGGTATTGTATCTAGTTTAAAAAGAACTGTAACAATGA
CTAATGAAGAAGGACAAACAGTTTCTACAAATGCTATCCAGACTGATGCTGCTATCAATCCTGGTAATTCAGGTGGAGCA
CTTATCAATATTGAAGGACAGGTTATTGGAATTAATTCTAGTAAAATTTCTTCTACATCAAATCAAACCTCAGGACAATC
GTCAGGAAATAGCGTTGAAGGTATGGGATTTGCCATTCCTTCAAATGATGTTGTTAAGATTATCAATCAACTTGAGAGTA
ACGGACAAGTAGAGAGACCTGCTCTAGGTATTTCTATGGCTGGATTAAGTAATTTACCATCCGATGTTATTAGTAAACTG
AAAATCCCAAGTAATGTTACTAATGGTATTGTAGTAGCATCTATCCAATCTGGCATGCCAGCTCAAGGCAAACTAAAGAA
ATACGATGTCATTACTAAAGTTGACGATAAAGAAGTAGTATCTCCAAGTGATTTACAAAGTTTACTCTATGGCCACCAGG
TAGGGGATTCCATAACAGTAACCTTTTATCGTGGTGAAAATAAACAAACAGTCACTATAAAACTTACTAAAACTAGTAAA
GATTTAGCTAAACAACGAGCAAATAACTAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (106-251)

• PDZ domain (PDZ_2) (300-395)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	63.104	96.088	0.606
htrA	Streptococcus gordonii str. Challis substr. CH1	57.357	98.044	0.562
htrA	Streptococcus mitis NCTC 12261	56.281	97.311	0.548
htrA	Streptococcus pneumoniae TIGR4	54.791	99.511	0.545
htrA	Streptococcus pneumoniae Rx1	54.791	99.511	0.545
htrA	Streptococcus pneumoniae D39	54.791	99.511	0.545
htrA	Streptococcus pneumoniae R6	54.791	99.511	0.545