Detailed information NTG0090213

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: LPC26_RS10415
• Genome accession: NZ_AP025162
• Coordinates: 2111323..2113485 (-)
• Length: 720 a.a.
• NCBI ID: WP_229265792.1
• Uniprot ID: -
• Organism: Lactobacillus crispatus strain KT-11
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 2106323..2118485

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LPC26_RS10370	-	2106600..2106809 (-)	210	WP_003549779.1	helix-turn-helix domain-containing protein	-
LPC26_RS10375	-	2106824..2107363 (-)	540	WP_060462273.1	hypothetical protein	-
LPC26_RS10380	-	2107368..2107550 (-)	183	WP_025014159.1	hypothetical protein	-
LPC26_RS10385	-	2107718..2107933 (-)	216	WP_060462274.1	hypothetical protein	-
LPC26_RS10390	-	2108003..2108197 (-)	195	WP_060462275.1	bacteriocin	-
LPC26_RS10395	-	2108215..2108466 (-)	252	WP_005726423.1	Blp family class II bacteriocin	-
LPC26_RS10400	-	2109059..2109256 (-)	198	WP_005721002.1	hypothetical protein	-
LPC26_RS10405	-	2109257..2110561 (-)	1305	WP_005721000.1	thioredoxin domain-containing protein	-
LPC26_RS10410	-	2110716..2111312 (-)	597	WP_005720997.1	hypothetical protein	-
LPC26_RS10415	comA	2111323..2113485 (-)	2163	WP_229265792.1	peptide cleavage/export ABC transporter	Regulator
LPC26_RS10420	-	2113609..2114409 (-)	801	WP_005720993.1	LytR/AlgR family response regulator transcription factor	-
LPC26_RS10425	-	2114402..2115730 (-)	1329	WP_060462277.1	sensor histidine kinase	-
LPC26_RS12015	-	2115718..2115849 (-)	132	WP_005720990.1	bacteriocin-like peptide, LSEI_2386 family	-
LPC26_RS10430	-	2115967..2117364 (-)	1398	WP_005720989.1	ATP-binding protein	-

Sequence

Protein

• Length: 720 a.a.
• Molecular weight: 81343.77 Da
• Isoelectric Point: 8.1038

>NTDB_id=90213 LPC26_RS10415 WP_229265792.1 2111323..2113485(-) (comA) [Lactobacillus crispatus strain KT-11]
MLLQYKSIYVPQVDESDCGVACLAMILKKYHSRVFLAHLRHSARTNLEGTTALGLVKTAQAFNLKTEAVKADMSLFDPDA
DIQYPFIVHVLKQGELLHYYVVIKATKNYLVIADPDPSVGLTKMSKEKFSQEWTGIALFMVPNDDFEPLKEKKQNLWSLF
PYMFKQKKLVTNIILAALLMTIISICSLYFLQGLIDTYIPSGTYQTLSILAIGLLIAYVFNSIFSYGQNFLLDILGQRLS
IDLNLQYIRHIFELPMEFFVTRRTGEITSRFSDASRIIDALASTVISLFLDLSIVIVMGIVLAIQNSTLFVITLLSLPIY
AVVILSFSKKFEKMNNDQMESNAVLSSSVIEDIQGIETIKALNSEQTRYRKIDSQFVDYLKKSFRYSKTESLQSALKTFI
QLSLNVIILWVGAKVVMNGQMSIGQLMTFNALLSYFVDPLQSIINLQPTLQSANVAQNRLNEVYMVKSEFQKDAQIRDAK
QLAGEIEYHHVDYHYGYGVDVLKDINLKIEPNDKLAIVGMSGSGKSTMVKLLVDFFSPSKGKLTFNGFNSTKVDKHVLRS
YVNYVPQTPYIFSGTIKENLLLGSRPDITEKDILKACQIAEIESEIEQLPLQFETKMDENAKILSGGQKQRLTIARALLS
PAKILIFDEATSGLDTITEKKVVDNLMKLKDKTIIFIAHRLAIAQRTNNIVVVDHGQIVEQGSHEKLMQKHGFYYNLVEN

Nucleotide

• Length: 2163 bp

>NTDB_id=90213 LPC26_RS10415 WP_229265792.1 2111323..2113485(-) (comA) [Lactobacillus crispatus strain KT-11]
ATGTTACTACAGTATAAATCAATTTATGTACCACAAGTAGACGAATCAGATTGTGGAGTTGCATGCTTAGCTATGATTCT
TAAAAAATATCATTCTAGAGTATTTTTAGCCCATTTACGTCATTCAGCCCGCACTAATTTAGAAGGGACTACCGCTCTGG
GCTTAGTTAAAACAGCACAAGCATTTAATCTAAAAACTGAAGCAGTTAAAGCTGACATGTCCTTGTTTGATCCTGATGCA
GACATTCAATATCCTTTCATCGTACACGTCTTAAAGCAAGGCGAATTACTCCACTATTATGTTGTGATTAAGGCAACCAA
AAATTATTTAGTGATTGCTGATCCGGATCCTAGCGTTGGTTTAACGAAAATGTCTAAAGAAAAGTTTTCTCAAGAATGGA
CGGGAATTGCCCTTTTTATGGTCCCAAATGATGATTTTGAGCCACTCAAAGAGAAAAAGCAAAATCTGTGGTCACTATTT
CCATACATGTTCAAACAAAAGAAACTAGTCACTAATATTATTTTGGCTGCTCTTTTGATGACAATCATTAGTATTTGTAG
CTTATACTTCTTGCAAGGCTTAATTGATACTTATATTCCTAGCGGTACATACCAAACTTTGTCGATCCTAGCTATTGGTT
TATTGATAGCATATGTTTTCAACTCTATCTTTTCTTACGGGCAAAATTTTCTATTGGATATTCTAGGTCAGCGATTAAGT
ATTGATCTTAACTTACAATACATTCGCCATATTTTTGAATTACCAATGGAATTCTTCGTAACTCGTAGAACAGGGGAAAT
TACCTCAAGGTTCTCTGATGCTAGTCGAATTATTGACGCACTCGCCAGTACAGTTATTTCATTATTTCTTGATCTTTCAA
TTGTAATTGTGATGGGAATAGTTTTGGCAATTCAAAATTCCACTCTATTTGTGATTACTCTACTGTCTTTGCCAATTTAT
GCAGTGGTGATTCTTAGCTTTTCTAAGAAATTTGAAAAGATGAATAATGATCAGATGGAGAGTAATGCTGTCTTAAGTTC
TTCAGTAATTGAAGATATTCAAGGAATTGAAACAATCAAAGCTTTAAATAGCGAACAAACACGTTATCGTAAGATTGATA
GTCAATTCGTCGATTACCTCAAGAAATCTTTTCGTTACAGTAAAACTGAATCTTTGCAGTCAGCTTTAAAGACCTTCATT
CAGTTATCTCTCAATGTAATTATCCTCTGGGTAGGGGCTAAGGTTGTAATGAACGGGCAGATGAGCATTGGTCAATTAAT
GACCTTCAACGCATTACTATCGTATTTTGTAGATCCACTTCAGAGCATTATTAATCTTCAACCAACTCTACAATCAGCTA
ATGTAGCACAAAATCGATTGAATGAAGTATACATGGTTAAGAGTGAGTTCCAGAAAGATGCTCAGATTAGGGATGCCAAG
CAATTAGCAGGTGAGATTGAATATCATCATGTTGACTATCATTATGGCTATGGAGTCGATGTATTAAAAGATATTAATTT
AAAAATCGAACCCAATGATAAGTTGGCAATCGTAGGGATGAGTGGCTCAGGTAAGTCTACTATGGTCAAACTTTTAGTTG
ATTTCTTCTCTCCAAGCAAAGGCAAGTTAACTTTTAATGGATTTAATTCTACTAAAGTAGATAAGCATGTCTTACGGTCA
TACGTAAACTATGTTCCCCAAACACCATACATCTTCTCAGGAACAATCAAAGAAAATCTGCTCTTAGGTAGTCGACCAGA
TATTACAGAAAAAGATATATTGAAAGCCTGTCAGATAGCAGAAATTGAGTCTGAAATCGAACAATTACCACTGCAGTTTG
AAACCAAGATGGATGAAAATGCCAAGATTTTATCCGGTGGGCAAAAGCAAAGGCTAACTATTGCACGTGCATTATTGTCA
CCGGCTAAAATTTTAATTTTTGATGAAGCCACTAGCGGGCTTGATACGATTACAGAGAAAAAAGTAGTAGATAATTTAAT
GAAATTAAAAGATAAAACGATTATTTTTATTGCTCATCGTTTAGCAATTGCACAAAGGACTAACAATATTGTGGTTGTAG
ATCATGGTCAAATTGTTGAGCAAGGAAGTCATGAGAAATTAATGCAGAAACATGGCTTTTACTATAACTTAGTTGAGAAT
TAG

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (171-440)

• Peptidase C39 family (Peptidase_C39) (9-144)

• ABC transporter (ABC_tran) (502-652)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis SK321	56.503	99.306	0.561
comA	Streptococcus pneumoniae D39	56.364	99.306	0.56
comA	Streptococcus pneumoniae R6	56.364	99.306	0.56
comA	Streptococcus mitis NCTC 12261	56.364	99.306	0.56
comA	Streptococcus pneumoniae Rx1	56.364	99.306	0.56
comA	Streptococcus pneumoniae TIGR4	56.224	99.306	0.558
comA	Streptococcus gordonii str. Challis substr. CH1	55.524	99.306	0.551
comA/nlmT	Streptococcus mutans UA159	53.531	98.333	0.526